Primary Site >> Esophagus Cancer
Gene >> GLI1
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Ref: Hedgehog signaling is activated in subsets of esophageal cancers. PMID: 16003737 Ref: Hedgehog: an attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response. PMID: 17085672 Ref: Gli-1 expression is associated with lymph node metastasis and tumor progression in esophageal squamous cell carcinoma. PMID: 17179732 |
Ref: Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals. PMID: 19513567 Ref: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. PMID: 19860666 |
Ref: Cross-signaling among phosphinositide-3 kinase, mitogen-activated protein kinase and sonic hedgehog pathways exists in esophageal cancer. PMID: 20839260 |
Ref: The crosstalk of mTOR/S6K1 and Hedgehog pathways. PMID: 22439934 |
Ref: Influence of smoothened siRNA on human esophageal cancer cell line EC9706 proliferation and apoptosis. PMID: 25262515 |
Ref: ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: identification of novel targets for concerted therapy concepts. PMID: 25435423 |
Ref: Targeting of miR-150 on Gli1 gene to inhibit proliferation and cell cycle of esophageal carcinoma EC9706. PMID: 29081413 |
Ref: The targeted regulation of Gli1 by miR-361 to inhibit epithelia-mesenchymal transition and invasion of esophageal carcinoma cells. PMID: 29125483 Ref: Gli is activated and promotes epithelial-mesenchymal transition in human esophageal adenocarcinoma. PMID: 29416661 |