Primary Site >> Colorectal Cancer

Gene >> GJB2

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Ref: A novel sensitive method to detect frameshift mutations in exonic repeat sequences of cancer-related genes.
PMID: 10545425
 Ref: Cells heterozygous for the ApcMin mutation have decreased gap junctional intercellular communication and connexin43 level, and reduced microtubule polymerization.
PMID: 12727791
Ref: [In situ expression of connexins in various carcinomas].
PMID: 12866956
 Ref: Connexin 26 correlates with Bcl-xL and Bax proteins expression in colorectal cancer.
PMID: 15770735
Ref: Alterations in connexin26 expression during colorectal carcinogenesis.
PMID: 16015037
Ref: Immunoprofiles of 11 biomarkers using tissue microarrays identify prognostic subgroups in colorectal cancer.
PMID: 16207476
 Ref: Insulin-like growth factor-I receptor correlates with connexin 26 and Bcl-xL expression in human colorectal cancer.
PMID: 17384270
 Ref: Profiling of selenomethionine responsive genes in colon cancer by microarray analysis.
PMID: 17374985
 Ref: Aberrant expression of connexin 26 is associated with lung metastasis of colorectal cancer.
PMID: 18245526
Ref: Overexpression of connexin 26 in carcinoma of the pancreas.
PMID: 18288393
 Ref: Clinical significance of the expression of connexin26 in colorectal cancer.
PMID: 20565955
 Ref: DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer.
PMID: 21406965
 Ref: E-cadherin and beta-catenin adhesion proteins correlate positively with connexins in colorectal cancer.
PMID: 24932249
 Ref: Connexins in colorectal cancer pathogenesis.
PMID: 24752574