Primary Site >> Colorectal Cancer

Gene >> GHRH

  • 2003
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  • 2009
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  • 2015
Ref: Acromegaly due to ectopic secretion of GHRH by bronchial carcinoid in a patient with empty sella.
PMID: 12739745
Ref: Antagonists of growth-hormone-releasing hormone: an emerging new therapy for cancer.
PMID: 18084344
Ref: Differential expression of GHRH receptor and its splice variant 1 in human normal and malignant mucosa of the oesophagus and colon.
PMID: 18575759
Ref: Essential role of p21/waf1 in the mediation of the anti-proliferative effects of GHRH antagonist JMR-132.
PMID: 18765563
Ref: GHRH antagonist causes DNA damage leading to p21 mediated cell cycle arrest and apoptosis in human colon cancer cells.
PMID: 19755849
Ref: GHRH antagonist when combined with cytotoxic agents induces S-phase arrest and additive growth inhibition of human colon cancer.
PMID: 23095641
Ref: Targeted therapy in advanced metastatic colorectal cancer: current concepts and perspectives.
PMID: 24876732
Ref: Potentiating effects of GHRH analogs on the response to chemotherapy.
PMID: 25648497