Primary Site >> Colorectal Cancer

Gene >> GCNT1

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Ref: Carcinoma-associated expression of core 2 beta-1,6-N-acetylglucosaminyltransferase gene in human colorectal cancer: role of O-glycans in tumor progression.
PMID: 9393734
Ref: Clinicopathological significance of core 2 beta1,6-N-acetylglucosaminyltransferase messenger RNA expressed in the pulmonary adenocarcinoma determined by in situ hybridization.
PMID: 11280791
Ref: Expression of the high-affinity selectin glycan ligand C2-O-sLeX by colon carcinoma cells.
PMID: 15596301
Ref: C2GnT-M is downregulated in colorectal cancer and its re-expression causes growth inhibition of colon cancer cells.
PMID: 16418723
Ref: Mucin biosynthesis: molecular cloning and expression of mouse mucus-type core 2 beta1,6 N-acetylglucosaminyltransferase.
PMID: 17591617
Ref: The high affinity selectin glycan ligand C2-O-sLex and mRNA transcripts of the core 2 beta-1,6-N-acetylglucosaminyltransferase (C2GnT1) gene are highly expressed in human colorectal adenocarcinomas.
PMID: 19267921
Ref: C2-O-sLeX glycoproteins are E-selectin ligands that regulate invasion of human colon and hepatic carcinoma cells.
PMID: 21283832
Ref: A non-enzymatic function of Golgi glycosyltransferases: mediation of Golgi fragmentation by interaction with non-muscle myosin IIA.
PMID: 23396488