Primary Site >> Colorectal Cancer
Gene >> GATA6
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Ref: Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs. PMID: 17390031 |
Ref: GATA6 promotes colon cancer cell invasion by regulating urokinase plasminogen activator gene expression. PMID: 21076612 |
Ref: Regulation of the tumor suppressor homeogene Cdx2 by HNF4alpha in intestinal cancer. PMID: 22986531 Ref: GATA6 predicts prognosis and hepatic metastasis of colorectal cancer. PMID: 23784465 |
Ref: The miR-363-GATA6-Lgr5 pathway is critical for colorectal tumourigenesis. PMID: 24452072 Ref: Activated protease receptor-2 induces GATA6 expression to promote survival in irradiated colon cancer cells. PMID: 24887481 Ref: The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression. PMID: 24952462 |
Ref: REG4 is a transcriptional target of GATA6 and is essential for colorectal tumorigenesis. PMID: 26387746 |
Ref: The miR-196b miRNA inhibits the GATA6 intestinal transcription factor and is upregulated in colon cancer patients. PMID: 27902469 Ref: Synergy between Auraptene, Ionizing Radiation, and Anticancer Drugs in Colon Adenocarcinoma Cells. PMID: 28675489 Ref: lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/beta-catenin signaling. PMID: 29035371 Ref: Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells. PMID: 29354128 |
Ref: beta-catenin, leucine-rich repeat-containing G protein-coupled receptor 5 and GATA-binding factor 6 are associated with the normal mucosa-adenoma-adenocarcinoma sequence of colorectal tumorigenesis. PMID: 29434936 Ref: MiR-455 functions as a tumor suppressor through targeting GATA6 in colorectal cancer. PMID: 29615149 Ref: Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis. PMID: 29706565 Ref: LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis. PMID: 30224759 Ref: Lack of APC somatic mutation is associated with early-onset colorectal cancer in African Americans. PMID: 30239619 |