Primary Site >> Colorectal Cancer

Gene >> GATA4

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Ref: Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter.
PMID: 18332107
Ref: GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer.
PMID: 19509152
Ref: Aberrant gene promoter methylation associated with sporadic multiple colorectal cancer.
PMID: 20098741
Ref: Mapping of liver-enriched transcription factors in the human intestine.
PMID: 20712053
Ref: DNA methylation of phosphatase and actin regulator 3 detects colorectal cancer in stool and complements FIT.
PMID: 22135045
Ref: Caudal homeobox protein Cdx-2 cooperates with Wnt pathway to regulate claudin-1 expression in colon cancer cells.
PMID: 22719836
Ref: DNA methylation analysis of SFRP2, GATA4/5, NDRG4 and VIM for the detection of colorectal cancer in fecal DNA.
PMID: 25202404
Ref: Phytochemical Indicaxanthin Inhibits Colon Cancer Cell Growth and Affects the DNA Methylation Status by Influencing Epigenetically Modifying Enzyme Expression and Activity.
PMID: 26439130
Ref: Identification of colorectal cancer-restricted microRNAs and their target genes based on high-throughput sequencing data.
PMID: 27069368
Ref: DNA methylation based biomarkers in colorectal cancer: A systematic review.
PMID: 27385266