Primary Site >> Colorectal Cancer
Gene >> GAB2
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Ref: Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects. PMID: 15059917 |
Ref: Clinical significance of GAB2, a scaffolding/docking protein acting downstream of EGFR in human colorectal cancer. PMID: 25029990 |
Ref: Gab2 is a novel prognostic factor for colorectal cancer patients. PMID: 26045784 Ref: Proteinase-activated receptor 2 promotes cancer cell migration through RNA methylation-mediated repression of miR-125b. PMID: 26354435 |
Ref: Gab2 facilitates epithelial-to-mesenchymal transition via the MEK/ERK/MMP signaling in colorectal cancer. PMID: 26754532 Ref: [Effect of jianpi-jiedu formula on tumor angiogenesis-relevant genes expression in colorectal cancer]. PMID: 28070042 |
Ref: BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines. PMID: 29326440 Ref: MicroRNA-485 plays tumour-suppressive roles in colorectal cancer by directly targeting GAB2. PMID: 29781037 Ref: LncRNA snaR upregulates GRB2-associated binding protein 2 and promotes proliferation of ovarian carcinoma cells. PMID: 30093110 |