Primary Site >> Liver Cancer

Gene >> FZD7

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Ref: Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma.
PMID: 15480989
Ref: Comparative genomics on Fzd7 orthologs.
PMID: 15870913
Ref: Oncogenic role of the frizzled-7/beta-catenin pathway in hepatocellular carcinoma.
PMID: 16098625
Ref: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs.
PMID: 17273804
Ref: Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells.
PMID: 18313787
Ref: Characterization of HuH6, Hep3B, HepG2 and HLE liver cancer cell lines by WNT/beta - catenin pathway, microRNA expression and protein expression profile.
PMID: 20937217
Ref: Pharmacological inhibition of Frizzled-7 displays anti-tumor properties in hepatocellular carcinoma.
PMID: 21055837
Ref: Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin.
PMID: 21314951
Ref: Frizzled7 as an emerging target for cancer therapy.
PMID: 22182510
Ref: MiR-27a modulates the MDR1/P-glycoprotein expression by inhibiting FZD7/beta-catenin pathway in hepatocellular carcinoma cells.
PMID: 24018051
Ref: Notch1 promotes hepatitis B virus X protein-induced hepatocarcinogenesis via Wnt/beta-catenin pathway.
PMID: 25017705
Ref: MiR-199a regulates cell proliferation and survival by targeting FZD7.
PMID: 25313882
Ref: De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas.
PMID: 27191501
Ref: Fibrous nests in human hepatocellular carcinoma express a Wnt-induced gene signature associated with poor clinical outcome.
PMID: 27545991
Ref: Agkihpin, a novel SVAE may inhibit the migration and invasion of liver cancer cells associated with the inversion of EMT induced by Wnt/beta-catenin signaling inhibition.
PMID: 27644877
Ref: Reversal effect of quercetin on multidrug resistance via FZD7/beta-catenin pathway in hepatocellular carcinoma cells.
PMID: 29747752
Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
PMID: 29786110