Primary Site >> Colorectal Cancer
Gene >> FZD5
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Ref: Frizzled-10, up-regulated in primary colorectal cancer, is a positive regulator of the WNT - beta-catenin - TCF signaling pathway. PMID: 11786918 Ref: Expression of WNT7A in human normal tissues and cancer, and regulation of WNT7A and WNT7B in human cancer. PMID: 12239632 |
Ref: Comparative genomics on ROR1 and ROR2 orthologs. PMID: 16211313 |
Ref: DNA methylation changes in genes frequently mutated in sporadic colorectal cancer and in the DNA repair and Wnt/beta-catenin signaling pathway genes. PMID: 24811787 |
Ref: Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors. PMID: 27869803 Ref: Molecular genetics and targeted therapy of WNT-related human diseases (Review). PMID: 28731148 |