Primary Site >> Colorectal Cancer
Gene >> FOXO1
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Ref: Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors. PMID: 11884591 Ref: Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway. PMID: 12145277 |
Ref: Involvement of the PI 3-kinase signaling pathway in progression of colon adenocarcinoma. PMID: 14578160 |
Ref: Mutant PIK3CA promotes cell growth and invasion of human cancer cells. PMID: 15950905 |
Ref: ILK over-expression in human colon cancer progression correlates with activation of beta-catenin, down-regulation of E-cadherin and activation of the Akt-FKHR pathway. PMID: 16278819 |
Ref: Wild-type APC regulates caveolin-1 expression in human colon adenocarcinoma cell lines via FOXO1a and C-myc. PMID: 18444242 Ref: LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins. PMID: 18794113 |
Ref: Rapamycin-mediated FOXO1 inactivation reduces the anticancer efficacy of rapamycin. PMID: 20392999 Ref: Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity. PMID: 20543840 Ref: Genetic profiles distinguish different types of hereditary ovarian cancer. PMID: 20811668 |
Ref: Knockdown of RON inhibits AP-1 activity and induces apoptosis and cell cycle arrest through the modulation of Akt/FoxO signaling in human colorectal cancer cells. PMID: 21901254 Ref: shRNA against CD44 inhibits cell proliferation, invasion and migration, and promotes apoptosis of colon carcinoma cells. PMID: 22076607 Ref: APC I1307K mutations and forkhead box gene (FOXO1A): another piece of an interesting correlation. PMID: 22180177 Ref: MicroRNA-223 regulates FOXO1 expression and cell proliferation. PMID: 22569260 |
Ref: MHY-449, a novel dihydrobenzofuro[4,5-b][1,8] naphthyridin-6-one derivative, induces apoptotic cell death through modulation of Akt/FoxO1 and ERK signaling in PC3 human prostate cancer cells. PMID: 24424889 Ref: Melatonin reduces endothelin-1 expression and secretion in colon cancer cells through the inactivation of FoxO-1 and NF-kappabeta. PMID: 24628039 Ref: Differential expression of miRNAs in colon cancer between African and Caucasian Americans: implications for cancer racial health disparities. PMID: 24865442 Ref: Genome-wide identification of FoxO-dependent gene networks in skeletal muscle during C26 cancer cachexia. PMID: 25539728 |
Ref: MicroRNA-96 promotes the proliferation of colorectal cancer cells and targets tumor protein p53 inducible nuclear protein 1, forkhead box protein O1 (FOXO1) and FOXO3a. PMID: 25369914 Ref: UDP-glucuronosyltransferase 1A determinates intracellular accumulation and anti-cancer effect of beta-lapachone in human colon cancer cells. PMID: 25692465 |
Ref: BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling. PMID: 26033966 |
Ref: Exploratory plasma proteomic analysis in a randomized crossover trial of aspirin among healthy men and women. PMID: 28542447 Ref: NLRC3 regulates cellular proliferation and apoptosis to attenuate the development of colorectal cancer. PMID: 28598238 Ref: Autophagy-related gene expression in colorectal cancer patients. PMID: 29254294 |
Ref: Histone deacetylase inhibitor trichostatin A and autophagy inhibitor chloroquine synergistically exert anti-tumor activity in H-ras transformed breast epithelial cells. PMID: 29344672 Ref: MicroRNA-544 promotes colorectal cancer progression by targeting forkhead box O1. PMID: 29422969 Ref: Decreased expression of ARHGAP15 promotes the development of colorectal cancer through PTEN/AKT/FOXO1 axis. PMID: 29867200 Ref: High-intensity eccentric training ameliorates muscle wasting in colon 26 tumor-bearing mice. PMID: 29894511 Ref: Knockdown of Mir-135b Sensitizes Colorectal Cancer Cells to Oxaliplatin-Induced Apoptosis Through Increase of FOXO1. PMID: 30071508 Ref: Interaction between Tumor-Associated Dendritic Cells and Colon Cancer Cells Contributes to Tumor Progression via CXCL1. PMID: 30115896 |