Primary Site >> Liver Cancer
Gene >> FOXM1
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Ref: Sustained hepatic expression of FoxM1B in transgenic mice has minimal effects on hepatocellular carcinoma development but increases cell proliferation rates in preneoplastic and early neoplastic lesions. PMID: 13679865 |
Ref: Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor. PMID: 15082532 |
Ref: New and unexpected: forkhead meets ARF. PMID: 15661532 Ref: The forkhead box m1 transcription factor is essential for embryonic development of pulmonary vasculature. PMID: 15817462 Ref: Loss of the forkhead transcription factor FoxM1 causes centrosome amplification and mitotic catastrophe. PMID: 15958562 |
Ref: Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice. PMID: 16452231 Ref: The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer. PMID: 16489016 |
Ref: A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment. PMID: 17173139 |
Ref: TIS21 negatively regulates hepatocarcinogenesis by disruption of cyclin B1-Forkhead box M1 regulation loop. PMID: 18393292 |
Ref: Knockdown of FoxM1 by siRNA interference decreases cell proliferation, induces cell cycle arrest and inhibits cell invasion in MHCC-97H cells in vitro. PMID: 20154714 Ref: Prognostic markers and putative therapeutic targets for hepatocellular carcinoma. PMID: 20176048 Ref: Negative regulation of the oncogenic transcription factor FoxM1 by thiazolidinediones and mithramycin. PMID: 20372080 Ref: Nuclear accumulation of glioma-associated oncogene 2 protein and enhanced expression of forkhead-box transcription factor M1 protein in human hepatocellular carcinoma. PMID: 20712011 |
Ref: Constitutive active/androstane receptor promotes hepatocarcinogenesis in a mouse model of non-alcoholic steatohepatitis. PMID: 21173431 Ref: Deregulation of FoxM1b leads to tumour metastasis. PMID: 21204266 Ref: Proteomic profiling revealed the functional networks associated with mitotic catastrophe of HepG2 hepatoma cells induced by 6-bromine-5-hydroxy-4-methoxybenzaldehyde. PMID: 21419150 Ref: Overexpression of Forkhead box M1 protein associates with aggressive tumor features and poor prognosis of hepatocellular carcinoma. PMID: 21431285 Ref: FOXM1 expression predicts the prognosis in hepatocellular carcinoma patients after orthotopic liver transplantation combined with the Milan criteria. PMID: 21482449 Ref: Micelle-encapsulated thiostrepton as an effective nanomedicine for inhibiting tumor growth and for suppressing FOXM1 in human xenografts. PMID: 21903609 |
Ref: MicroRNA-135a contributes to the development of portal vein tumor thrombus by promoting metastasis in hepatocellular carcinoma. PMID: 21888875 Ref: FOXM1: From cancer initiation to progression and treatment. PMID: 21978825 Ref: AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2, PMID: 21993994 Ref: Liver tumor formation by a mutant retinoblastoma protein in the transgenic mice is caused by an upregulation of c-Myc target genes. PMID: 22182413 Ref: Upregulated FoxM1 expression induced by hepatitis B virus X protein promotes tumor metastasis and indicates poor prognosis in hepatitis B virus-related hepatocellular carcinoma. PMID: 22613004 Ref: The TNF-alpha/ROS/HIF-1-induced upregulation of FoxMI expression promotes HCC proliferation and resistance to apoptosis. PMID: 22831955 Ref: Gene network analysis leads to functional validation of pathways linked to cancer cell growth and survival. PMID: 22930530 |
Ref: Cancer genetics and genomics of human FOX family genes. PMID: 23022474 Ref: Casticin induces growth suppression and cell cycle arrest through activation of FOXO3a in hepatocellular carcinoma. PMID: 23064420 Ref: Negative regulation of transcription factor FoxM1 by p53 enhances oxaliplatin-induced senescence in hepatocellular carcinoma. PMID: 23262037 Ref: C-terminus-deleted FoxM1 is expressed in cancer cell lines and induces chromosome instability. PMID: 23615399 |
Ref: ACP5, a direct transcriptional target of FoxM1, promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma. PMID: 23604121 Ref: LXRalpha-mediated downregulation of FOXM1 suppresses the proliferation of hepatocellular carcinoma cells. PMID: 23812424 Ref: Steroid receptor co-activator-3 promotes osteosarcoma progression through up-regulation of FoxM1. PMID: 24282087 Ref: Silencing of FOXM1 transcription factor expression by adenovirus-mediated RNA interference inhibits human hepatocellular carcinoma growth. PMID: 24577129 Ref: Gd-EOB-DTPA-enhanced magnetic resonance imaging and alpha-fetoprotein predict prognosis of early-stage hepatocellular carcinoma. PMID: 24700365 Ref: Korean Scutellaria baicalensis Georgi methanol extracts inhibits metastasis via the Forkhead Box M1 activity in hepatocellular carcinoma cells. PMID: 24910406 Ref: The potential contributions of a Y-located protooncogene and its X homologue in sexual dimorphisms in hepatocellular carcinoma. PMID: 25017435 |
Ref: Sorafenib inhibits proliferation and invasion of human hepatocellular carcinoma cells via up-regulation of p53 and suppressing FoxM1. PMID: 25557114 Ref: FoxM1 overexpression promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma. PMID: 25574092 Ref: miR-34a induces cellular senescence via modulation of telomerase activity in human hepatocellular carcinoma by targeting FoxM1/c-Myc pathway. PMID: 25686834 Ref: Essential roles of FoxM1 in Ras-induced liver cancer progression and in cancer cells with stem cell features. PMID: 25828473 Ref: Up-regulation of miR-877 induced by paclitaxel inhibits hepatocellular carcinoma cell proliferation though targeting FOXM1. PMID: 25973036 Ref: FoxM1 influences mouse hepatocellular carcinoma metastasis in vitro. PMID: 26045783 Ref: USP39 promotes the growth of human hepatocellular carcinoma in vitro and in vivo. PMID: 26081192 Ref: FoxM1 transactivates PTTG1 and promotes colorectal cancer cell migration and invasion. PMID: 26264222 Ref: TCGA whole-transcriptome sequencing data reveals significantly dysregulated genes and signaling pathways in hepatocellular carcinoma. PMID: 26276037 Ref: Prognostic Value of FOXM1 in Patients with Malignant Solid Tumor: A Meta-Analysis and System Review. PMID: 26451068 |
Ref: Elevated expression of FoxM1 promotes the tumor cell proliferation in hepatocellular carcinoma. PMID: 26289845 Ref: Peroxiredoxin II promotes hepatic tumorigenesis through cooperation with Ras/Forkhead box M1 signaling pathway. PMID: 26500057 Ref: Aberrantly activated Gli2-KIF20A axis is crucial for growth of hepatocellular carcinoma and predicts poor prognosis. PMID: 27036048 Ref: Immunotherapy based on dendritic cells pulsed with CTPFoxM1 fusion protein protects against the development of hepatocellular carcinoma. PMID: 27351282 Ref: MicroRNA-216b is downregulated in hepatocellular carcinoma and inhibits HepG2 cell growth by targeting Forkhead box protein M1. PMID: 27383303 Ref: Peroxiredoxin I is important for cancer-cell survival in Ras-induced hepatic tumorigenesis. PMID: 27517622 Ref: Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-beta pathway. PMID: 27612430 |
Ref: Crosstalk between microRNA-122 and FOX family genes in HepG2 cells. PMID: 27895094 Ref: Increased expression of Forkhead box M1 transcription factor is associated with clinicopathological features and confers a poor prognosis in human hepatocellular carcinoma. PMID: 28002884 Ref: A novel peptide, 9R-P201, strongly inhibits the viability, proliferation and migration of liver cancer HepG2 cells and induces apoptosis by down-regulation of FoxM1 expression. PMID: 28012972 Ref: Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer. PMID: 28249813 Ref: FOXM1 regulates glycolysis in hepatocellular carcinoma by transactivating glucose transporter 1 expression. PMID: 28260073 Ref: USP39 regulates the growth of SMMC-7721 cells via FoxM1. PMID: 28413501 Ref: PDZ binding kinase, regulated by FoxM1, enhances malignant phenotype via activation of beta-Catenin signaling in hepatocellular carcinoma. PMID: 28525379 Ref: A positive feedback loop of long noncoding RNA CCAT2 and FOXM1 promotes hepatocellular carcinoma growth. PMID: 28744394 Ref: USP5 promotes tumorigenesis and progression of pancreatic cancer by stabilizing FoxM1 protein. PMID: 28807830 Ref: FoxM1 promotes epithelial-mesenchymal transition of hepatocellular carcinoma by targeting Snai1. PMID: 28849004 Ref: The CCCTC-binding factor (CTCF)-forkhead box protein M1 axis regulates tumour growth and metastasis in hepatocellular carcinoma. PMID: 28862757 Ref: Sex-Differential Responses of Tumor Promotion-Associated Genes and Dysregulation of Novel Long Noncoding RNAs in Constitutive Androstane Receptor-Activated Mouse Liver. PMID: 28903501 |
Ref: Inhibition of CIP2A attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma. PMID: 29175329 Ref: High MYBL2 expression and transcription regulatory activity is associated with poor overall survival in patients with hepatocellular carcinoma. PMID: 29274707 Ref: A gene expression signature of FOXM1 predicts the prognosis of hepatocellular carcinoma. PMID: 29303511 Ref: Effects of Wnt-1 blockade in DEN-induced hepatocellular adenomas of mice. PMID: 29399175 Ref: YAP-associated chromosomal instability and cholangiocarcinoma in mice. PMID: 29464042 Ref: Key signaling pathways, genes and transcription factors associated with hepatocellular carcinoma. PMID: 29658607 Ref: FOXM1 promotes proliferation in human hepatocellular carcinoma cells by transcriptional activation of CCNB1. PMID: 29705704 Ref: Targeting the mevalonate pathway is a novel therapeutic approach to inhibit oncogenic FoxM1 transcription factor in human hepatocellular carcinoma. PMID: 29765517 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: miR-199a-3p Modulates MTOR and PAK4 Pathways and Inhibits Tumor Growth in a Hepatocellular Carcinoma Transgenic Mouse Model. PMID: 29858083 Ref: Clinicopathological and prognostic significance of FoxM1 in hepatocellular carcinoma patients: a meta-analysis. PMID: 29950861 Ref: Downreguation of FoxM1 by miR-214 inhibits proliferation and migration in hepatocellular carcinoma. PMID: 29973656 Ref: [YAP induces chromosomal instability in liver cancer patients]. PMID: 30206654 Ref: miR-1306-3p targets FBXL5 to promote metastasis of hepatocellular carcinoma through suppressing snail degradation. PMID: 30219228 Ref: MicroRNA8765p inhibits the progression of glioblastoma multiforme by directly targeting Forkhead box M1. PMID: 30365126 |