Primary Site >> Pancreatic Cancer

Gene >> FOXC2

  • 2004
  • 2009
  • 2010
  • 2016
Ref: Human FOX gene family (Review).
PMID: 15492844
Ref: Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades.
PMID: 19424602
Ref: Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals.
PMID: 19513567
Ref: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.
PMID: 19860666
Ref: Integrative genomic analyses of CXCR4: transcriptional regulation of CXCR4 based on TGFbeta, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors.
PMID: 20043076
Ref: FOXC2 is up-regulated in pancreatic ductal adenocarcinoma and promotes the growth and migration of cancer cells.
PMID: 26733175