Primary Site >> Colorectal Cancer

Gene >> FOXC2

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Ref: Gene expression of mesenchyme forkhead 1 (FOXC2) significantly correlates with the degree of lymph node metastasis in colorectal cancer.
PMID: 22216698
Ref: Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon.
PMID: 22363130
Ref: Isolation and characterization of calcium sensing receptor null cells: a highly malignant and drug resistant phenotype of colon cancer.
PMID: 23055106
Ref: Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells.
PMID: 24760019
Ref: Elevated HOXB9 expression promotes differentiation and predicts a favourable outcome in colon adenocarcinoma patients.
PMID: 25025961
Ref: FOXC2 promotes colorectal cancer proliferation through inhibition of FOXO3a and activation of MAPK and AKT signaling pathways.
PMID: 25069037
Ref: FOXC2 promotes colorectal cancer metastasis by directly targeting MET.
PMID: 25381815
Ref: Overexpression of forkhead Box C2 promotes tumor metastasis and indicates poor prognosis in colon cancer via regulating epithelial-mesenchymal transition.
PMID: 26269761
Ref: Downregulation of Foxc2 enhances apoptosis induced by 5-fluorouracil through activation of MAPK and AKT pathways in colorectal cancer.
PMID: 26893778
Ref: Genistein induces apoptosis of colon cancer cells by reversal of epithelial-to-mesenchymal via a Notch1/NF-kappaB/slug/E-cadherin pathway.
PMID: 29202800
Ref: NFATC3-PLA2G15 Fusion Transcript Identified by RNA Sequencing Promotes Tumor Invasion and Proliferation in Colorectal Cancer Cell Lines.
PMID: 29909608