Primary Site >> Colorectal Cancer
Gene >> FLT4
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Ref: Circulating lymphangiogenic growth factors in gastrointestinal solid tumors, could they be of any clinical significance? PMID: 18461654 Ref: VEGF-D expression correlates with colorectal cancer aggressiveness and is downregulated by cetuximab. PMID: 18636661 |
Ref: K-ras mutation status correlates with the expression of VEGFR1, VEGFR2, and PDGFRalpha in colorectal cancer. PMID: 19936766 Ref: Inhibiting tumor growth of colorectal cancer by blocking the expression of vascular endothelial growth factor receptor 3 using interference vector-based RNA interference. PMID: 19956902 |
Ref: Expression of GLI1 correlates with expression of lymphangiogenesis proteins, vascular endothelial growth factor C and vascular endothelial growth factor receptor 3, in colorectal cancer. PMID: 23336661 Ref: YL529, a novel, orally available multikinase inhibitor, potently inhibits angiogenesis and tumour growth in preclinical models. PMID: 23594209 |
Ref: Regorafenib (BAY 73-4506): antitumor and antimetastatic activities in preclinical models of colorectal cancer. PMID: 24347491 |
Ref: Neuropilin-2 mediates lymphangiogenesis of colorectal carcinoma via a VEGFC/VEGFR3 independent signaling. PMID: 25543087 Ref: Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis. PMID: 25605009 Ref: Vascular endothelial growth factor C disrupts the endothelial lymphatic barrier to promote colorectal cancer invasion. PMID: 25754161 Ref: Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer. PMID: 26243311 Ref: Angiogenesis-related protein expression in bevacizumab-treated metastatic colorectal cancer: NOTCH1 detrimental to overall survival. PMID: 26394830 Ref: MTA1 Is Up-regulated in Colorectal Cancer and Is Inversely Correlated with Lymphatic Metastasis. PMID: 26543080 |
Ref: Heterogeneity of Vascular Endothelial Growth Factor Receptors 1, 2, 3 in Primary Human Colorectal Carcinoma. PMID: 27272777 Ref: A taspine derivative supresses Caco-2 cell growth by competitively targeting EphrinB2 and regulating its pathway. PMID: 27460008 |
Ref: Taspine derivative 12k suppressed A549 cell migration through the Wnt/beta-catenin and EphrinB2 signaling pathway. PMID: 28049091 Ref: Next-generation sequencing traces human induced pluripotent stem cell lines clonally generated from heterogeneous cancer tissue. PMID: 28596815 |
Ref: Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene. PMID: 29665843 |