Primary Site >> Biliary tract Cancer

Gene >> FHIT

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Ref: Fragile histidine triad gene abnormalities in the pathogenesis of gallbladder carcinoma.
PMID: 12057912
 Ref: Genetic abnormalities in pancreatic cancer.
PMID: 12537585
Ref: Homozygous deletion scanning in hepatobiliary tumor cell lines reveals alternative pathways for liver carcinogenesis.
PMID: 12668978
Ref: Alteration of the fragile histidine triad gene in intrahepatic cholangiocarcinoma.
PMID: 12867802
Ref: Expression of Fhit, Mlh1, and P53 protein in human gallbladder carcinoma.
PMID: 12969785
 Ref: Promoter methylation and loss of coding exons of the fragile histidine triad (FHIT) gene in intrahepatic cholangiocarcinomas.
PMID: 16343073
 Ref: Promoter methylation profile in gallbladder cancer.
PMID: 16699861
 Ref: Frequent epigenetic inactivation of chromosome 3p candidate tumor suppressor genes in gallbladder carcinoma.
PMID: 17084965
Ref: Significance of PML and p53 protein as molecular prognostic markers of gallbladder carcinomas.
PMID: 18158568
 Ref: Inverse correlation of aberrant expression of fragile histidine triad (FHIT) protein with cyclin D1 protein and prognosis in Chinese patients with cholangiocarcinoma.
PMID: 18618300
Ref: [Gene methylation patterns in digestive tumors].
PMID: 18769787
Ref: Biomarkers in carcinoma of the gallbladder.
PMID: 23495740
 Ref: Genetic and expression alterations in association with the sarcomatous change of cholangiocarcinoma cells.
PMID: 19287191
Ref: Coordinate loss of fragile gene expression in pancreatobiliary cancers: correlations among markers and clinical features.
PMID: 19434452
 Ref: FHIT promotes the apoptosis of QBC939 by reducing the expression of cyclin D1.
PMID: 21830375
 Ref: Sequential occurrence of preneoplastic lesions and accumulation of loss of heterozygosity in patients with gallbladder stones suggest causal association with gallbladder cancer.
PMID: 24827397
 Ref: Genome wide DNA copy number analysis in cholangiocarcinoma using high resolution molecular inversion probe single nucleotide polymorphism assay.
PMID: 26260902