Primary Site >> Liver Cancer
Gene >> FGF21
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Ref: Forced expression of hepatocyte-specific fibroblast growth factor 21 delays initiation of chemically induced hepatocarcinogenesis. PMID: 16929488 |
Ref: Mini-review: endocrine actions of fibroblast growth factor 19. PMID: 18179175 |
Ref: FGF19-induced hepatocyte proliferation is mediated through FGFR4 activation. PMID: 20018895 |
Ref: Thiazolidinediones are potent inducers of fibroblast growth factor 21 expression in the liver. PMID: 21720023 |
Ref: Understanding the structure-function relationship between FGF19 and its mitogenic and metabolic activities. PMID: 22396171 |
Ref: Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21. PMID: 25082895 |
Ref: Hepatic PTEN deficiency improves muscle insulin sensitivity and decreases adiposity in mice. PMID: 25234947 Ref: Forced expression of fibroblast growth factor 21 reverses the sustained impairment of liver regeneration in hPPARalpha(PAC) mice due to dysregulated bile acid synthesis. PMID: 25991671 Ref: Combined Serum Biomarkers in Non-Invasive Diagnosis of Non-Alcoholic Steatohepatitis. PMID: 26121037 Ref: Loss of FGF21 in diabetic mouse during hepatocellular carcinogenetic transformation. PMID: 26175944 |
Ref: Mapping the response of human fibroblast growth factor 21 (FGF21) promoter to serum availability and lipoic acid in HepG2 hepatoma cells. PMID: 26691139 Ref: Roles of FGFs As Paracrine or Endocrine Signals in Liver Development, Health, and Disease. PMID: 27148532 Ref: Lack of fibroblast growth factor 21 accelerates metabolic liver injury characterized by steatohepatities in mice. PMID: 27293995 |
Ref: Downregulation of pathways implicated in liver inflammation and tumorigenesis of glycogen storage disease type Ia mice receiving gene therapy. PMID: 28334808 Ref: Amelioration of late-onset hepatic steatosis in IDH2-deficient mice. PMID: 28415887 Ref: Multiplexed gene expression profiling identifies the FGFR4 pathway as a novel biomarker in intrahepatic cholangiocarcinoma. PMID: 28445152 Ref: Diverse Changes of Circulating Fibroblast Growth Factor 21 Levels in Hepatitis B Virus-Related Diseases. PMID: 29184085 |
Ref: Deficiency of fibroblast growth factor 21 (FGF21) promotes hepatocellular carcinoma (HCC) in mice on a long term obesogenic diet. PMID: 29753678 |