Primary Site >> Biliary tract Cancer

Gene >> FGF19

  • 2014
  • 2015
  • 2017
  • 2018
Ref: Fibroblast growth factor receptor 4 promotes progression and correlates to poor prognosis in cholangiocarcinoma.
PMID: 24565842
Ref: Fibroblast Growth Factor 19 Activates the Unfolded Protein Response and Mitogen-Activated Protein Kinase Phosphorylation in H-69 Cholangiocyte Cells.
PMID: 29093991
 Ref: Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma.
PMID: 25608663
Ref: Genome wide DNA copy number analysis in cholangiocarcinoma using high resolution molecular inversion probe single nucleotide polymorphism assay.
PMID: 26260902
 Ref: Multiplexed gene expression profiling identifies the FGFR4 pathway as a novel biomarker in intrahepatic cholangiocarcinoma.
PMID: 28445152
Ref: A Phase 1 study of ARQ 087, an oral pan-FGFR inhibitor in patients with advanced solid tumours.
PMID: 28972963
 Ref: Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma.
PMID: 29460642