Primary Site >> Colorectal Cancer

Gene >> FCGR2A

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Ref: Cytotoxic functions of blood mononuclear cells in patients with colorectal carcinoma treated with mAb 17-1A and granulocyte/macrophage-colony-stimulating factor.
PMID: 1638551
Ref: Prothymosin alpha 1 effects in vitro on chemotaxis, cytotoxicity and oxidative response of neutrophils from melanoma, colorectal and breast tumor patients.
PMID: 9568546
Ref: Irinotecan-induced immune thrombocytopenia.
PMID: 9636839
Ref: Bevacizumab immune complexes activate platelets and induce thrombosis in FCGR2A transgenic mice.
PMID: 18983497
Ref: Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer.
PMID: 22117530
Ref: Multifactorial pharmacogenetic analysis in colorectal cancer patients receiving 5-fluorouracil-based therapy together with cetuximab-irinotecan.
PMID: 22486600
Ref: Predicting skin toxicity according to EGFR polymorphisms in patients with colorectal cancer receiving antibody against EGFR.
PMID: 24222141
Ref: Fc-gamma Receptor Polymorphisms, Cetuximab Therapy, and Survival in the NCIC CTG CO.17 Trial of Colorectal Cancer.
PMID: 27179112
Ref: FCGR, Cetuximab, and Colorectal Cancer Survival-Letter.
PMID: 27697992
Ref: Germline polymorphisms as biomarkers of tumor response in colorectal cancer patients treated with anti-EGFR monoclonal antibodies: a systematic review and meta-analysis.
PMID: 27897268
Ref: Associations between single-nucleotide polymorphisms and inflammatory bowel disease-associated colorectal cancers in inflammatory bowel disease patients: a meta-analysis.
PMID: 28243990
Ref: The influence of FCGR2A and FCGR3A polymorphisms on the survival of patients with recurrent or metastatic squamous cell head and neck cancer treated with cetuximab.
PMID: 28719596
Ref: Fc-gamma receptor polymorphisms, cetuximab therapy, and overall survival in the CCTG CO.20 trial of metastatic colorectal cancer.
PMID: 30318772