Primary Site >> Biliary tract Cancer

Gene >> FBXW7

  • 2007
  • 2014
  • 2015
  • 2016
  • 2017
  • 2018
Ref: FBXW7/hCDC4 is a general tumor suppressor in human cancer.
PMID: 17909001
 Ref: Loss of FBXW7 expression is associated with poor prognosis in intrahepatic cholangiocarcinoma.
PMID: 24552289
Ref: Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications.
PMID: 25536104
 Ref: FBXW7 suppresses epithelial-mesenchymal transition, stemness and metastatic potential of cholangiocarcinoma cells.
PMID: 25749036
 Ref: Comprehensive genomic profiling of extrahepatic cholangiocarcinoma reveals a long tail of therapeutic targets.
PMID: 26500333
Ref: Cadherin-6 is a putative tumor suppressor and target of epigenetically dysregulated miR-429 in cholangiocarcinoma.
PMID: 27593557
Ref: KRAS Mutation as a Potential Prognostic Biomarker of Biliary Tract Cancers.
PMID: 28008299
 Ref: E3 ubiquitin ligase FBW7alpha inhibits cholangiocarcinoma cell proliferation by downregulating c-Myc and cyclin E.
PMID: 28184929
 Ref: Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation.
PMID: 29386660