Primary Site >> Stomach Cancer
Gene >> FASN
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Ref: Fatty acid synthase is highly expressed in carcinoma, adenoma and in regenerative epithelium and intestinal metaplasia of the stomach. PMID: 11903600 |
Ref: Liver-type fatty acid-binding protein is highly expressed in intestinal metaplasia and in a subset of carcinomas of the stomach without association with the fatty acid synthase status in the carcinoma. PMID: 15051923 Ref: Expression of heart-type fatty acid-binding protein in human gastric carcinoma and its association with tumor aggressiveness, metastasis and poor prognosis. PMID: 15459486 |
Ref: Inhibition of fatty acid synthase by Orlistat accelerates gastric tumor cell apoptosis in culture and increases survival rates in gastric tumor bearing mice in vivo. PMID: 19381703 Ref: Inhibitory effects of four plants flavonoids extracts on fatty acid synthase. PMID: 25084411 |
Ref: High overexpression of fatty acid synthase is associated with poor survival in Chinese patients with gastric carcinoma. PMID: 23226763 |
Ref: Elevated levels of serum fatty acid synthase in patients with gastric carcinoma. PMID: 24527066 |
Ref: Expression of Fatty Acid Synthase Negatively Correlates with PTEN and Predicts Peritoneal Dissemination of Human Gastric Cancer. PMID: 26514456 Ref: A concordant expression pattern of fatty acid synthase and membranous human epidermal growth factor receptor 2 exists in gastric cancer and is associated with a poor prognosis in gastric adenocarcinoma patients. PMID: 26622804 |
Ref: Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites. PMID: 26811494 Ref: Overexpression of fatty acid synthase predicts a poor prognosis for human gastric cancer. PMID: 26936091 |
Ref: Quantitative proteomic analysis reveals that proteins required for fatty acid metabolism may serve as diagnostic markers for gastric cancer. PMID: 27884752 Ref: Identification of diagnostic markers involved in the pathogenesis of gastric cancer through iTRAQ-based quantitative proteomics. PMID: 28180141 Ref: MACC1 decreases the chemosensitivity of gastric cancer cells to oxaliplatin by regulating FASN expression. PMID: 28339092 |
Ref: Small interfering RNA-mediated knockdown of fatty acid synthase attenuates the proliferation and metastasis of human gastric cancer cells via the mTOR/Gli1 signaling pathway. PMID: 29928446 Ref: Anti-proliferative activity of Origanum vulgare inhibited lipogenesis and induced mitochondrial mediated apoptosis in human stomach cancer cell lines. PMID: 30372889 |