Primary Site >> Biliary tract Cancer

Gene >> FASLG

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Ref: Cholangiocarcinomas express Fas ligand and disable the Fas receptor.
PMID: 10573518
 Ref: Up-regulation of fas ligand at early stages and down-regulation of Fas at progressed stages of intrahepatic cholangiocarcinoma reflect evasion from immune surveillance.
PMID: 11003620
 Ref: Fas counterattack in cholangiocarcinoma: a mechanism for immune evasion in human hilar cholangiocarcinomas.
PMID: 11854917
 Ref: [The "Fas counterattack": a mechanism for immune evasion in human hilar cholangiocarcinomas].
PMID: 12133481
Ref: Regulative effect of IFN-gamma on the Fas/Fas L system of cholangiocarcinoma cells.
PMID: 12411152
 Ref: Anatomic and molecular pathology of intrahepatic cholangiocarcinoma.
PMID: 14598145
 Ref: Fas and Fas ligand: Expression and soluble circulating levels in bile duct carcinoma.
PMID: 15138553
 Ref: Action and mechanism of Fas and Fas ligand in immune escape of gallbladder carcinoma.
PMID: 15968727
Ref: Susceptibility of cholangiocarcinoma cells to parthenolide-induced apoptosis.
PMID: 16024633
 Ref: Reciprocal co-expression of Fas and Fas ligand in human cholangiocarcinoma.
PMID: 17786316
 Ref: Genetic and expression alterations in association with the sarcomatous change of cholangiocarcinoma cells.
PMID: 19287191
 Ref: The role of MAPK-ERK pathway in 67-kDa laminin receptor-induced FasL expression in human cholangiocarcinoma cells.
PMID: 20101459
Ref: Primary and malignant cholangiocytes undergo CD40 mediated Fas dependent apoptosis, but are insensitive to direct activation with exogenous Fas ligand.
PMID: 21103345
 Ref: [Expression of WW domain containing oxidoreductase gene in cholangiocarcinoma and its effect on the biological behavior of cancer cell line RBE].
PMID: 21612698
 Ref: Death receptor (DR4) haplotypes are associated with increased susceptibility of gallbladder carcinoma in north Indian population.
PMID: 24587306
Ref: UHRF1 depletion suppresses growth of gallbladder cancer cells through induction of apoptosis and cell cycle arrest.
PMID: 24756644
 Ref: A Multiple Interaction Analysis Reveals ADRB3 as a Potential Candidate for Gallbladder Cancer Predisposition via a Complex Interaction with Other Candidate Gene Variations.
PMID: 26602921
 Ref: Activation of Fas/FasL pathway and the role of c-FLIP in primary culture of human cholangiocarcinoma cells.
PMID: 29089545