Primary Site >> Biliary tract Cancer

Gene >> FAS

  • 1996
  • 1999
  • 2010
  • 2016
Ref: Expression of apoptosis, proliferating cell nuclear antigen, and apoptosis-related antigens (bcl-2, c-myc, Fas, Lewis(y) and p53) in human cholangiocarcinomas and hepatocellular carcinomas.
PMID: 8916146
Ref: Apoptosis and tumorigenesis in human cholangiocarcinoma cells. Involvement of Fas/APO-1 (CD95) and calmodulin.
PMID: 10393851
Ref: Primary and malignant cholangiocytes undergo CD40 mediated Fas dependent apoptosis, but are insensitive to direct activation with exogenous Fas ligand.
PMID: 21103345
Ref: TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro.
PMID: 26420419