Primary Site >> Colorectal Cancer

Gene >> FANCD2

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Ref: Repeated sequences in CASPASE-5 and FANCD2 but not NF1 are targets for mutation in microsatellite-unstable acute leukemia/myelodysplastic syndrome.
PMID: 15886296
Ref: FANCD2 mRNA overexpression is a bona fide indicator of lymph node metastasis in human colorectal cancer.
PMID: 20339950
Ref: Exome-wide somatic microsatellite variation is altered in cells with DNA repair deficiencies.
PMID: 25402475
Ref: Tailoring heated intraperitoneal mitomycin C for peritoneal metastases originating from colorectal carcinoma: a translational approach to improve survival.
PMID: 25668003
Ref: Overexpression of Rad51C splice variants in colorectal tumors.
PMID: 25669972
Ref: Germline Mutations in FAN1 Cause Hereditary Colorectal Cancer by Impairing DNA Repair.
PMID: 26052075
Ref: mTORC1 and DNA-PKcs as novel molecular determinants of sensitivity to Chk1 inhibition.
PMID: 26471831
Ref: CRISPR-Cas9-based target validation for p53-reactivating model compounds.
PMID: 26595461
Ref: Pharmacological targeting of RAD6 enzyme-mediated translesion synthesis overcomes resistance to platinum-based drugs.
PMID: 28490629
Ref: The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells.
PMID: 29559578