Primary Site >> Colorectal Cancer
Gene >> FANCB
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Ref: Use of limitations of radiolabeled anti-CEA antibodies and their fragments for photoscanning detection of human colorectal carcinomas. PMID: 7279698 |
Ref: Improved radioimaging and tumor localization with monoclonal F(ab')2. PMID: 6339689 Ref: [Gastrointestinal tumors: chemotherapeutic preparations]. PMID: 6852723 |
Ref: Monoclonal antibodies to breast cancer-associated antigens as potential reagents in the management of breast cancer. PMID: 6498759 |
Ref: The characteristics of blood-borne radiolabels and the effect of anti-mouse IgG antibodies on localization of radiolabeled monoclonal antibody in cancer patients. PMID: 3861794 |
Ref: Detection of colorectal carcinoma by emission-computerized tomography after injection of 123I-labeled Fab or F(ab')2 fragments from monoclonal anti-carcinoembryonic antigen antibodies. PMID: 3484753 Ref: Polyclonal and monoclonal anti-CEA antibodies in immunolocalization of colorectal cancer. PMID: 3495029 |
Ref: Lymphoma, melanoma, colon cancer: diagnosis and treatment with radiolabeled monoclonal antibodies. The 1986 Eugene P. Pendergrass New Horizons Lecture. PMID: 3498971 Ref: [Immunoscintigraphy using radio-labeled monoclonal antibodies. Development of a method of cancer diagnosis and hopes for a new form of therapy]. PMID: 3499666 Ref: Penetration and binding of radiolabeled anti-carcinoembryonic antigen monoclonal antibodies and their antigen binding fragments in human colon multicellular tumor spheroids. PMID: 3545451 Ref: Pharmacokinetics of the monoclonal antibody B72.3 and its fragments labeled with either 125I or 111In. PMID: 3802096 |
Ref: Lateral diffusion of the secretory component (SC) in the basolateral membrane of the human colon carcinoma cell line HT29 assessed with fluorescence recovery after photobleaching. PMID: 3192635 Ref: Radiolocalisation of an anti-CEA monoclonal antibody (FO23C5) and its fragments in a colon carcinoma xenograft model. PMID: 3235854 |
Ref: Imaging of colorectal carcinoma with radiolabeled antibodies. PMID: 2678479 Ref: Clinical value of immunoscintigraphy in colorectal carcinoma patients: a prospective study. PMID: 2795205 |
Ref: [Use of radiolabeled monoclonal antibodies for diagnostic imaging]. PMID: 2235337 Ref: Comparison of tumor targeting in nude mice by murine monoclonal antibodies directed against different human colorectal cancer antigens. PMID: 2297729 Ref: Radioactive gold cluster immunoconjugates: potential agents for cancer therapy. PMID: 2341283 Ref: [Acquisition of Philadelphia chromosome with bcr rearrangement concomitant with transformation of refractory anemia with excess of blasts with 8 trisomy into acute myelogenous leukemia]. PMID: 2366338 |
Ref: Evaluation of procedures for the fixation and processing of human tissue for immunohistochemical analysis of human monoclonal antibodies. PMID: 1714786 Ref: A novel heterobifunctional linker for formyl to thiol coupling. PMID: 1725255 Ref: Bifunctional antibody: a binary radiopharmaceutical delivery system for imaging colorectal carcinoma. PMID: 1742739 Ref: SPECT anti-CEA monoclonal antibody detection of occult colorectal carcinoma metastases. PMID: 1752096 Ref: Evaluation of the 323/A3 monoclonal antibody and the use of technetium-99m-labeled 323/A3 Fab' for the detection of pan adenocarcinoma. PMID: 1917518 Ref: Changes in leucocyte populations following murine bifunctional antibody infusion in colon cancer patients. PMID: 2025955 |
Ref: Bispecific-antibody-mediated targeting of radiolabeled bivalent haptens: theoretical, experimental and clinical results. PMID: 1428406 Ref: 99mTc-IMMU-4 monoclonal antibody scan in colorectal cancer. A prospective study. PMID: 1444794 Ref: Localization by whole-body autoradiography of intact and fragmented radiolabeled antibodies in a metastatic human colonic cancer model. PMID: 1577618 Ref: Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms. PMID: 1596900 Ref: Human/mouse chimeric antibodies show low reactivity with human anti-murine antibodies (HAMA). PMID: 1739617 |
Ref: [Further study on the value of M2-type pyruvate kinase in the diagnosis of primary hepatocarcinoma]. PMID: 8174464 Ref: Gene transfer into respiratory epithelial cells by targeting the polymeric immunoglobulin receptor. PMID: 8227356 Ref: Colon carcinoma cells blocked in polarization exhibit increased expression of carcinoembryonic antigen. PMID: 8241027 Ref: Monoclonal antibody imaging in patients with colorectal cancer and increasing levels of serum carcinoembryonic antigen. Experience with ZCE-025 and IMMU-4 monoclonal antibodies and proposed directions for clinical trials. PMID: 8389662 Ref: Anticarcinoembryonic antigen immunoscintigraphy with a 99mTc-Fab' fragment (Immu 4) in primary and recurrent colorectal cancer. A prospective study. PMID: 8404384 Ref: Bispecific monoclonal antibody-mediated targeting of an indium-111-labeled DTPA dimer to primary colorectal tumors: pharmacokinetics, biodistribution, scintigraphy and immune response. PMID: 8410279 Ref: Colorectal cancer imaging with iodine-123-labeled CEA monoclonal antibody fragments. PMID: 8418273 Ref: Enhanced in vitro tumor cell retention and internalization of antibody derivatized with synthetic peptides. PMID: 8431507 Ref: Imaging of colorectal carcinoma with technetium-99m radiolabeled Fab' fragments. PMID: 8511605 |
Ref: Monoclonal antibody-superantigen fusion proteins: tumor-specific agents for T-cell-based tumor therapy. PMID: 8090750 Ref: Physiologically based pharmacokinetic model for specific and nonspecific monoclonal antibodies and fragments in normal tissues and human tumor xenografts in nude mice. PMID: 8137258 Ref: In vivo efficacy of neocarzinostatin coupled with Fab human/mouse chimeric monoclonal antibody A7 against human colorectal cancer. PMID: 8144398 Ref: Radioimmunodetection of colorectal carcinoma using technetium-99m-labeled Fab' fragments of the IMMU-4 anti-carcinoembryonic antigen monoclonal antibody. PMID: 8306268 |
Ref: Biodistribution and tumor localization of 111In-labeled unmodified and modified F(ab')2 fragments of human monoclonal IgM (16.88) in a nude mouse model. PMID: 7550017 Ref: Tumor targeting and pharmacokinetics of unmodified and modified F(ab)2 fragments of an anti-CEA murine monoclonal antibody (Immu-14). PMID: 7550018 Ref: Immunotherapy of human colon cancer by antibody-targeted superantigens. PMID: 7553685 Ref: A cross-linked monoclonal antibody fragment for improved tumor targeting. PMID: 7599261 Ref: Tumor-reactive superantigens suppress tumor growth in humanized SCID mice. PMID: 7635573 Ref: Expression of blood group Lewis b determinant from Lewis a: association of this novel alpha (1,2)-L-fucosylating activity with the Lewis type alpha (1,3/4)-L-fucosyltransferase. PMID: 7718581 Ref: Comparison of complete versus fragmented technetium-99m-labeled anti-CEA monoclonal antibodies for immunoscintigraphy in colorectal cancer. PMID: 7884505 |
Ref: Antibody-targeted superantigen therapy induces tumor-infiltrating lymphocytes, excessive cytokine production, and apoptosis in human colon carcinoma. PMID: 8566049 Ref: Murine bispecific antibody 1A10 directed to human transferrin receptor and a 42-kDa tumor-associated glycoprotein. PMID: 8625561 Ref: Clinical utility of external immunoscintigraphy with the IMMU-4 technetium-99m Fab' antibody fragment in patients undergoing surgery for carcinoma of the colon and rectum: results of a pivotal, phase III trial. The Immunomedics Study Group. PMID: 8708720 Ref: Isolation, purification and biological activity of major docetaxel metabolites from human feces. PMID: 8781781 Ref: Pharmacokinetics of iodine-125 CC49 monoclonal antibody in patients with colon cancer. PMID: 10851502 |
Ref: Cancer imaging with radiolabeled antibodies: new advances with technetium-99m-labeled monoclonal antibody Fab' fragments, especially CEA-Scan and prospects for therapy. PMID: 9239599 Ref: [Probe-guided surgery of colorectal carcinoma]. PMID: 9273809 Ref: Oncogenic c-Ki-ras but not oncogenic c-Ha-ras up-regulates CEA expression and disrupts basolateral polarity in colon epithelial cells. PMID: 9346938 Ref: Use of carcinoembryonic antigen radioimmunodetection and computed tomography for predicting the resectability of recurrent colorectal cancer. PMID: 9389396 Ref: Clinical experience with CD64-directed immunotherapy. An overview. PMID: 9435876 |
Ref: A single-chain immunotoxin against carcinoembryonic antigen that suppresses growth of colorectal carcinoma cells. PMID: 9829749 Ref: MHC class II-independent, Vbeta-specific activation of T cells by superantigen mutants fused to anti-tumor Fab fragments: implications for use in treatment of human colon carcinoma. PMID: 9852214 |
Ref: Breast cancer imaging with radiolabeled antibodies. PMID: 9990682 Ref: Tumor targeting with newly designed biparatopic antibodies directed against two different epitopes of the carcinoembryonic antigen (CEA). PMID: 10188732 Ref: High-linear energy transfer (LET) alpha versus low-LET beta emitters in radioimmunotherapy of solid tumors: therapeutic efficacy and dose-limiting toxicity of 213Bi- versus 90Y-labeled CO17-1A Fab' fragments in a human colonic cancer model. PMID: 10363986 Ref: Generation of anti-p53 Fab fragments from individuals with colorectal cancer using phage display. PMID: 10438972 |
Ref: Clinical and technical considerations for imaging colorectal cancers with technetium-99m-labeled antiCEA Fab' fragment. PMID: 10763776 Ref: A3--a novel colon and pancreatic cancer reactive antibody from a primate phage library selected using intact tumour cells. PMID: 10918198 Ref: FDG PET and immunoscintigraphy with 99mTc-labeled antibody fragments for detection of the recurrence of colorectal carcinoma. PMID: 11037995 Ref: Antibody-conjugated MHC class I tetramers can target tumor cells for specific lysis by T lymphocytes. PMID: 11093131 Ref: Cure of metastatic human colonic cancer in mice with radiolabeled monoclonal antibody fragments. PMID: 11156250 |
Ref: Isolation of human antibodies against the central DNA binding domain of p53 from an individual with colorectal cancer using antibody phage display. PMID: 11555596 Ref: Biokinetics of a F(ab')3 iodine-131 labeled antigen binding construct (Mab 35) directed against CEA in patients with colorectal carcinoma. PMID: 11776754 Ref: [Inhibition of the growth of hepatoma and hepatic metastasis by pingyangmycin conjugated with Fab' fragment of monoclonal antibody]. PMID: 11798873 Ref: An antiproliferative norditerpene dilactone, Nagilactone C, from Podocarpus neriifolius. PMID: 11824527 Ref: Construction and selection of the natural immune Fab antibody phage display library from patients with colorectal cancer. PMID: 11854907 Ref: Immunoscintigraphy and intra-operative radioimmunodetection in the treatment of colorectal carcinoma. PMID: 12790934 |
Ref: Polyclonal anti-colorectal cancer Fab phage display library selected in one round using density gradient centrifugation to separate antigen-bound and free phage. PMID: 11852119 Ref: Cloning, isolation and characterization of human tumor in situ monoclonal antibodies. PMID: 11904732 Ref: Cancer-associated cleavage of cytokeratin 8/18 heterotypic complexes exposes a neoepitope in human adenocarcinomas. PMID: 11923318 Ref: Tumour targeting of humanised cross-linked divalent-Fab' antibody fragments: a clinical phase I/II study. PMID: 11986771 Ref: A human immunoglobulin G1 antibody originating from an in vitro-selected Fab phage antibody binds avidly to tumor-associated MUC1 and is efficiently internalized. PMID: 12000712 Ref: Target validation for genomics using peptide-specific phage antibodies: a study of five gene products overexpressed in colorectal cancer. PMID: 12209988 Ref: Adenovirus-mediated intratumoral lymphotactin gene transfer potentiates the antibody-targeted superantigen therapy of cancer. PMID: 12226740 Ref: [Comparative study of CEA antibody scan and computed tomography scan in the follow-up of patients with colorectal cancer]. PMID: 12236910 Ref: [Expression and identification of phage display library for Fab fragments of colorectal cancer-related antibodies]. PMID: 12376247 Ref: Correlation of red marrow radiation dosimetry with myelotoxicity: empirical factors influencing the radiation-induced myelotoxicity of radiolabeled antibodies, fragments and peptides in pre-clinical and clinical settings. PMID: 12396708 Ref: Generation of anti-colorectal cancer fab phage display libraries with a high percentage of diverse antigen-reactive clones. PMID: 12470278 |
Ref: A universal pretargeting system for cancer detection and therapy using bispecific antibody. PMID: 12543788 Ref: Expression of a prototypic anti-colorectal cancer polyclonal antibody library in mammalian cells. PMID: 12880683 |
Ref: Reagents and methods for PET using bispecific antibody pretargeting and 68Ga-radiolabeled bivalent hapten-peptide-chelate conjugates. PMID: 14734668 Ref: Generation and preliminary characterization of an antibody library with preferential reactivity to human colorectal cancer cells as compared to normal human blood cells. PMID: 15019288 Ref: (99m)Tc-Cys-Gly-Gly-Affibody ZHER2:342 PMID: 20641196 Ref: (111)In-Benzyl-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-ZHER2:342 PMID: 20641264 Ref: (111)In-(1-isothiocyanatobenzyl-3-methyldiethylenetriaminepentaaetic acid)-anti-TAG-72 humanized CH2 domain-deleted antibody PMID: 20641320 Ref: (111)In-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid- Affibody ZHER2:342-pep2 PMID: 20641379 Ref: (111)In-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-T84.66 minibody PMID: 20641400 Ref: Radioiodinated anti-TAG-72 CC49 tetravalent single-chain Fv antibody PMID: 20641419 Ref: Radioiodinated anti-TAG-72 non-covalently linked CC49 divalent single-chain Fv antibody PMID: 20641456 Ref: (111)In-CHX-A"-diethylenepentaacetic acid-Affibody ZHER2:2395-Cys PMID: 20641462 Ref: Radioiodinated T84.66 minibody PMID: 20641489 Ref: (111)In-CHX-A"-Diethylenetriamine pentaacetic acid-(ZEGFR:955)2 PMID: 20641502 Ref: (111)In-Benzyl-diethylenetriaminepentaacetic acid-ZHER2:342 PMID: 20641524 Ref: Radioiodinated-anti-TAG-72 covalently linked CC49 divalent single-chain Fv antibody PMID: 20641580 Ref: (99m)Tc-Hydrazinonicotinamide-anti-TAG-72 CC49 divalent single-chain Fv monoclonal antibody PMID: 20641631 Ref: (111)In-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-T84.66 diabody PMID: 20641644 Ref: (111)In-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-AB.Fab4D5 PMID: 20641705 Ref: (99m)Tc-Hydrazinonicotinamide-anti-TAG-72 CC49 tetravalent single-chain Fv monoclonal antibody PMID: 20641718 Ref: Radioiodinated anti-TAG-72 CC49 Fab' antibody fragment PMID: 20641734 Ref: [(111)In]-Labeled 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-heat-stable human Escherichia coli enterotoxin PMID: 20641763 Ref: Radioiodinated anti-TAG-72 CC49 (Fab')2 antibody fragment PMID: 20641775 Ref: (131)I-NP-4 anti-CEA monoclonal antibody PMID: 20641780 Ref: (99m)Tc-Affibody ZHER2:2395-Cys PMID: 20641788 Ref: (111)In-BZ-Diethylenetriaminepentaacetic acid-ZEGFR:1907 PMID: 20641849 Ref: (99m)Tc-Arcitumomab PMID: 20641871 Ref: Radioiodinated anti-CEA monoclonal antibody NP-4 F(ab )2 fragment PMID: 20641898 Ref: (111)In-1,4,7,10-tetraazacyclododecane-1,4,7-tris-acetic acid-10-maleimidoethylacetamide-Affibody ZHER2:2395-Cys PMID: 20641906 Ref: (99m)Tc-Mercaptoacetyl-Ser-Ser-Ser-Affibody ZHER2:342 PMID: 20641924 Ref: (99m)Tc-Mercaptoacetyl-Gly-Gly-Gly-Affibody ZHER2:342 PMID: 20641926 Ref: (99m)Tc-Mercaptoacetyl-Glu-Glu-Glu-Affibody ZHER2:342 PMID: 20641930 Ref: (125)I-Labeled anti-epidermal growth factor receptor human Fab antibody fragment PMID: 20642017 Ref: Alexa Fluor 750-ZHER2:342 Affibody PMID: 20662137 Ref: DY-682-Albumin-binding domain-fused-ZHER2:342 Affibody PMID: 20845546 Ref: IRDye 800-Anti-epidermal growth factor receptor Affibody PMID: 20845547 Ref: (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-synthetic HER2 specific Affibody ZHER2:342-pep2 PMID: 21086574 Ref: [(99m)Tc(CO)3](+)-Labeled anti-epidermal growth factor receptor (HER2) affibody ZHER2:342 with a hexa-histidine tag (H6) on the N-terminal PMID: 21290629 Ref: [(99m)Tc(CO)3](+)-Labeled anti-epidermal growth factor receptor (HER2) affibody ZHER2:342 with a tri-(histidine-glutamate) peptide tag (HE)3 on the N-terminal PMID: 21290630 Ref: [(99m)Tc(CO)3](+)-Labeled anti-epidermal growth factor receptor (HER2) affibody ZHER2:342 with a hexa-histidine tag (H6) on the C-terminal PMID: 21290634 Ref: Alexa Fluor 750-albumin-binding domain-fused-(ZHER2:342)2 Affibody PMID: 21491705 Ref: (18)F-1,4,7-Triazacyclononane-1,4,7-triacetic acid-10-maleimidoethylacetamide-Affibody ZHER2:2395 PMID: 22479718 Ref: (125)I-Labeled mouse anti-human carbonic anhydrase IX monoclonal antibody PMID: 22675743 Ref: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-(Gly-Ser-Gly)-Lys-Cys-Cys-Tyr-Ser-Leu PMID: 22787682 Ref: (64)Cu-Bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane-(Gly-Ser-Gly) -Lys-Cys-Cys-Tyr-Ser-Leu PMID: 22787683 Ref: (64)Cu-1,4,7-Triazacyclononane-1,4-diacetic acid-(Gly-Ser-Gly)-Lys-Cys-Cys-Tyr-Ser-Leu PMID: 22787684 Ref: (99m)Tc(CO)3-Anti-carcinoembryonic antigen (CEA) humanized CEA5 graft nanobody PMID: 22855965 Ref: Cy5.5-Ac-Cys-ZEGFR:1907 PMID: 22973578 Ref: [(111)In-1,4,7-Triazacyclononane,1-glutaric acid-4,7-acetic acid-10-maleimidoethylacetamide-Cys(61)]-Affibody ZHER2:2395 PMID: 22993871 Ref: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-human serum albumin-Ac-Cys-ZEGFR:1907 PMID: 23035309 Ref: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7-tris-acetic acid-10-maleimidethylacetamide-Ac-Cys-ZEGFR:1907 PMID: 23035311 Ref: QD800-Polyethylene glycol-Cys-ZHER2:342 Affibody PMID: 23101053 Ref: ZHER2:342 Affibody-polyethylene glycol-superparamagnetic iron oxide nanoparticles PMID: 23101054 Ref: N-[2-(4-[(18)F]Fluorobenzamido)ethyl]maleimide-Cys-ZEGFR:1907 PMID: 23136679 Ref: (177)Lu-1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid-human serum albumin-Ac-Cys-ZEGFR:1907 PMID: 23166961 Ref: Cy5.5-8-Amino-octanoic acid-Ser-Cys-Pro-Pro-Trp-Gln-Glu-Trp-His-Asn-Phe-Met-Pro-Phe-NH2 PMID: 23166962 Ref: (68)Ga-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-HER2-specific Affibody ZHER2:2891 PMID: 23256220 Ref: N(epsilon)-(3-[(131)I]Iodobenzoyl)-Lys(5)-N(alpha)-maleimido-Gly(1)-GEEEK-anti-HE R2 nanobody 5F7GGC PMID: 23556153 Ref: IRDye 800-albumin-binding domain-fused-ZHER2:342 Affibody PMID: 23785735 |
Ref: Blockade of platelet-derived growth factor receptor-beta by CDP860, a humanized, PEGylated di-Fab', leads to fluid accumulation and is associated with increased tumor vascularized volume. PMID: 15466784 Ref: The structure of an antitumor C(H)2-domain-deleted humanized antibody. PMID: 15854653 Ref: Recombinant polyclonal antibodies for cancer therapy. PMID: 16052504 |
Ref: Structure-function studies of two synthetic anti-vascular endothelial growth factor Fabs and comparison with the Avastin Fab. PMID: 16373345 Ref: [Screening and preliminary analysis of colorectal carcinoma-associated antigen genes]. PMID: 16503520 Ref: Four new neo-clerodane diterpenoid alkaloids from Scutellaria barbata with cytotoxic activities. PMID: 16755060 Ref: EGFR-targeted immunoliposomes derived from the monoclonal antibody EMD72000 mediate specific and efficient drug delivery to a variety of colorectal cancer cells. PMID: 16777680 |
Ref: Targeted gene therapy of LS174 T human colon carcinoma by anti-TAG-72 immunoliposomes. PMID: 18309354 |
Ref: Preparation and in-vitro bioactivity of a novel superantigen conjugate targeting bladder carcinoma. PMID: 19589228 |
Ref: Detection of collagen triple helix repeat containing-1 and nuclear factor (erythroid-derived 2)-like 3 in colorectal cancer. PMID: 22321245 |
Ref: Tumour antigen targeted monoclonal antibodies incorporating a novel multimerisation domain significantly enhance antibody dependent cellular cytotoxicity against colon cancer. PMID: 23871153 Ref: Computational modeling of an epidermal growth factor receptor single-mutation resistance to cetuximab in colorectal cancer treatment. PMID: 24219403 Ref: Characterization of human colorectal cancer MDR1/P-gp Fab antibody. PMID: 24348182 |
Ref: Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES. PMID: 26627827 |
Ref: New Strategies Using Antibody Combinations to Increase Cancer Treatment Effectiveness. PMID: 29312320 |
Ref: Silencing of Intestinal Glycoprotein CD98 by Orally Targeted Nanoparticles Enhances Chemosensitization of Colon Cancer. PMID: 29860836 Ref: Fab-conjugated PLGA nanoparticles effectively target cancer cells expressing human CD44v6. PMID: 30267881 |