Primary Site >> Colorectal Cancer

Gene >> FABP6

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Ref: The bile acid nuclear receptor FXR and the bile acid binding protein IBABP are differently expressed in colon cancer.
PMID: 15309887
Ref: Fatty acid binding protein 6 is overexpressed in colorectal cancer.
PMID: 16951225
Ref: Sodium taurocholate inhibits intestinal adenoma formation in APCMin/+ mice, potentially through activation of the farnesoid X receptor.
PMID: 20194350
Ref: Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-kappaB signaling in the intestine.
PMID: 21540105
Ref: Gene expression profiling of serrated polyps identifies annexin A10 as a marker of a sessile serrated adenoma/polyp.
PMID: 23595865
Ref: Inactivation of Adenomatous Polyposis Coli Reduces Bile Acid/Farnesoid X Receptor Expression through Fxr gene CpG Methylation in Mouse Colon Tumors and Human Colon Cancer Cells.
PMID: 26609171
Ref: A 15-gene signature for prediction of colon cancer recurrence and prognosis based on SVM.
PMID: 27998790
Ref: Western Diet Deregulates Bile Acid Homeostasis, Cell Proliferation, and Tumorigenesis in Colon.
PMID: 28416481
Ref: The long variant of human ileal bile acid-binding protein associated with colorectal cancer exhibits sub-cellular localization and lipid binding behaviour distinct from those of the common isoform.
PMID: 28689989
Ref: An integrated study on TFs and miRNAs in colorectal cancer metastasis and evaluation of three co-regulated candidate genes as prognostic markers.
PMID: 30193961