Primary Site >> Stomach Cancer
Gene >> EZH2
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Ref: Expression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer. PMID: 16734726 |
Ref: Immunohistochemical analysis of pRb2/p130, VEGF, EZH2, p53, p16(INK4A), p27(KIP1), p21(WAF1), Ki-67 expression patterns in gastric cancer. PMID: 16998811 |
Ref: Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells. PMID: 18377425 Ref: Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation. PMID: 18430739 |
Ref: Enhancer of zeste homolog 2 expression is associated with tumor cell proliferation and metastasis in gastric cancer. PMID: 20132185 Ref: BCL2L10 is frequently silenced by promoter hypermethylation in gastric cancer. PMID: 20428828 Ref: The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer. PMID: 20631058 Ref: MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion. PMID: 20712078 |
Ref: Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer. PMID: 22450781 Ref: Immunohistochemical analysis of polycomb group protein expression in advanced gastric cancer. PMID: 22520951 Ref: Correlation of epigenetic aberrance with STAT3 signaling pathway in gastric carcinogenesis. PMID: 22562532 Ref: TP53 genomic status regulates sensitivity of gastric cancer cells to the histone methylation inhibitor 3-deazaneplanocin A (DZNep). PMID: 22675170 Ref: Prognostic significance of overexpression of EZH2 and H3k27me3 proteins in gastric cancer. PMID: 22994729 |
Ref: CagA mediates epigenetic regulation to attenuate let-7 expression in Helicobacter pylori-related carcinogenesis. PMID: 22936674 Ref: SUZ12 depletion suppresses the proliferation of gastric cancer cells. PMID: 23735840 Ref: GKN1-miR-185-DNMT1 axis suppresses gastric carcinogenesis through regulation of epigenetic alteration and cell cycle. PMID: 23846337 Ref: Enhancer of zeste homolog 2 activates wnt signaling through downregulating CXXC finger protein 4. PMID: 23949225 Ref: Gastric cancer: epidemiologic aspects. PMID: 24011243 Ref: Functional analysis of the NH2-terminal hydrophobic region and BRICHOS domain of GKN1. PMID: 24099765 |
Ref: EZH2 genetic variants affect risk of gastric cancer in the Chinese Han population. PMID: 22228224 Ref: GKN2 contributes to the homeostasis of gastric mucosa by inhibiting GKN1 activity. PMID: 24151046 Ref: Expression of B-cell-specific Moloney murine leukemia virus integration site 1 mRNA and protein in gastric cancer. PMID: 24393364 Ref: Inhibiting enhancer of zeste homolog 2 promotes cellular senescence in gastric cancer cells SGC-7901 by activation of p21 and p16. PMID: 24588771 Ref: Role of C9orf140 in the promotion of colorectal cancer progression and mechanisms of its upregulation via activation of STAT5, beta-catenin and EZH2. PMID: 24608043 Ref: MicroRNA-124 inhibits proliferation and induces apoptosis by directly repressing EZH2 in gastric cancer. PMID: 24658854 Ref: Role of EZH2 protein expression in gastric carcinogenesis among Asians: a meta-analysis. PMID: 24705718 Ref: Inhibition enhancer of zeste homologue 2 promotes senescence and apoptosis induced by doxorubicin in p53 mutant gastric cancer cells. PMID: 24738879 Ref: TET1 exerts its tumor suppressor function by interacting with p53-EZH2 pathway in gastric cancer. PMID: 24804542 Ref: The role of gastrokine 1 in gastric cancer. PMID: 25328759 |
Ref: DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression. PMID: 25595591 Ref: [DZNep raises miR-200c expression to delay the invasion and migration of MGC-803 gastric carcinoma cells]. PMID: 25672630 Ref: siRNA silencing EZH2 reverses cisplatin-resistance of human non-small cell lung and gastric cancer cells. PMID: 25824776 Ref: microRNA-217 inhibits tumor progression and metastasis by downregulating EZH2 and predicts favorable prognosis in gastric cancer. PMID: 25869101 Ref: Long noncoding RNA PVT1 indicates a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically regulating p15 and p16. PMID: 25890171 Ref: Genome-wide transcriptional profiling analysis reveals annexin A6 as a novel EZH2 target gene involving gastric cellular proliferation. PMID: 25947258 Ref: Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus. PMID: 26004298 Ref: Long noncoding RNA HOXA-AS2 promotes gastric cancer proliferation by epigenetically silencing P21/PLK3/DDIT3 expression. PMID: 26384350 Ref: Microchidia protein 2, MORC2, downregulates the cytoskeleton adapter protein, ArgBP2, via histone methylation in gastric cancer cells. PMID: 26476214 Ref: Prognostic significance of EZH2 expression in patients with digestive cancers: a meta-analysis. PMID: 26629110 Ref: EZH2 Mediates the Regulation of S100A4 on E-cadherin Expression and the Proliferation, Migration of Gastric Cancer Cells. PMID: 26897964 |
Ref: Long intergenic non-coding RNA 00152 promotes tumor cell cycle progression by binding to EZH2 and repressing p15 and p21 in gastric cancer. PMID: 26799422 Ref: Prognostic significance of EZH2 expression in patients with oesophageal cancer: a meta-analysis. PMID: 26859127 Ref: MALAT1 long ncRNA promotes gastric cancer metastasis by suppressing PCDH10. PMID: 26871474 Ref: The novel EZH2 inhibitor, GSK126, suppresses cell migration and angiogenesis via down-regulating VEGF-A. PMID: 26898301 Ref: Long non-coding RNA LINC00628 functions as a gastric cancer suppressor via long-range modulating the expression of cell cycle related genes. PMID: 27272474 Ref: Long noncoding RNA HULC promotes colorectal carcinoma progression through epigenetically repressing NKD2 expression. PMID: 27496341 Ref: Long noncoding RNA XIST acts as an oncogene in non-small cell lung cancer by epigenetically repressing KLF2 expression. PMID: 27501756 Ref: Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression. PMID: 27620004 Ref: MicroRNA-126 increases chemosensitivity in drug-resistant gastric cancer cells by targeting EZH2. PMID: 27622325 Ref: LncRNA HOXA11-AS Promotes Proliferation and Invasion of Gastric Cancer by Scaffolding the Chromatin Modification Factors PRC2, LSD1, and DNMT1. PMID: 27651312 Ref: Long non-coding RNA CCAT2 promotes gastric cancer proliferation and invasion by regulating the E-cadherin and LATS2. PMID: 27904778 Ref: STAT3 signaling drives EZH2 transcriptional activation and mediates poor prognosis in gastric cancer. PMID: 27938379 Ref: Single Nucleotide Polymorphism of the Enhancer of Zeste Homolog 2 Gene rs2072408 is Associated with Lymph Node Metastasis and Depth of Primary Tumor Invasion in Gastric Cancer. PMID: 28164661 |
Ref: Long noncoding RNA ZFAS1 promotes gastric cancer cells proliferation by epigenetically repressing KLF2 and NKD2 expression. PMID: 27246976 Ref: Long noncoding RNA HOXA-AS2 represses P21 and KLF2 expression transcription by binding with EZH2, LSD1 in colorectal cancer. PMID: 28112720 Ref: Long noncoding AGAP2-AS1 is activated by SP1 and promotes cell proliferation and invasion in gastric cancer. PMID: 28209205 Ref: Long Noncoding RNA LINC00673 Is Activated by SP1 and Exerts Oncogenic Properties by Interacting with LSD1 and EZH2 in Gastric Cancer. PMID: 28214253 Ref: Epigenomic Promoter Alterations Amplify Gene Isoform and Immunogenic Diversity in Gastric Adenocarcinoma. PMID: 28320776 Ref: Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer. PMID: 28441948 Ref: Long noncoding RNA UCA1 induced by SP1 promotes cell proliferation via recruiting EZH2 and activating AKT pathway in gastric cancer. PMID: 28569779 Ref: LncRNA SNHG6 is Associated with Poor Prognosis of Gastric Cancer and Promotes Cell Proliferation and EMT through Epigenetically Silencing p27 and Sponging miR-101-3p. PMID: 28683446 Ref: Role of ARPC2 in Human Gastric Cancer. PMID: 28694563 Ref: Reprogramming Antagonizes the Oncogenicity of HOXA13-Long Noncoding RNA HOTTIP Axis in Gastric Cancer Cells. PMID: 28782268 Ref: The pseudogene derived long noncoding RNA DUXAP8 promotes gastric cancer cell proliferation and migration via epigenetically silencing PLEKHO1 expression. PMID: 28881724 Ref: LncRNA TRERNA1 Function as an Enhancer of SNAI1 Promotes Gastric Cancer Metastasis by Regulating Epithelial-Mesenchymal Transition. PMID: 28918030 Ref: TET-Mediated Sequestration of miR-26 Drives EZH2 Expression and Gastric Carcinogenesis. PMID: 28923852 Ref: LncRNA DANCR promotes migration and invasion through suppression of lncRNA-LET in gastric cancer cells. PMID: 28951520 Ref: HOX transcript antisense intergenic RNA represses E-cadherin expression by binding to EZH2 in gastric cancer. PMID: 28970725 Ref: Long noncoding RNA SNHG20 promotes gastric cancer progression by inhibiting p21 expression and regulating the GSK-3beta/ beta-catenin signaling pathway. PMID: 29113337 Ref: Long non-coding RNA SNHG15 inhibits P15 and KLF2 expression to promote pancreatic cancer proliferation through EZH2-mediated H3K27me3. PMID: 29137412 Ref: Long noncoding RNA LINC00673 epigenetically suppresses KLF4 by interacting with EZH2 and DNMT1 in gastric cancer. PMID: 29221147 Ref: Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer. PMID: 29760541 Ref: Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer. PMID: 30079558 |
Ref: The polycomb group protein EZH2 induces epithelial-mesenchymal transition and pluripotent phenotype of gastric cancer cells by binding to PTEN promoter. PMID: 29335012 Ref: HSF1, in association with MORC2, downregulates ArgBP2 via the PRC2 family in gastric cancer cells. PMID: 29339121 Ref: CBX7 regulates stem cell-like properties of gastric cancer cells via p16 and AKT-NF-kappaB-miR-21 pathways. PMID: 29422082 Ref: Long non-coding RNA CASC15 regulates gastric cancer cell proliferation, migration and epithelial mesenchymal transition by targeting CDKN1A and ZEB1. PMID: 29489064 Ref: Lentivirus-mediated overexpression of miR-124 suppresses growth and invasion by targeting JAG1 and EZH2 in gastric cancer. PMID: 29731896 Ref: Upregulation of the long noncoding RNA FOXD2-AS1 promotes carcinogenesis by epigenetically silencing EphB3 through EZH2 and LSD1, and predicts poor prognosis in gastric cancer. PMID: 29789713 Ref: Long noncoding RNA SNHG6 regulates p21 expression via activation of the JNK pathway and regulation of EZH2 in gastric cancer cells. PMID: 30031062 Ref: The role of the long non-coding RNA HOXA11-AS in promoting proliferation and metastasis of malignant tumors. PMID: 30095197 |