Primary Site >> Colorectal Cancer
Gene >> ESR1
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Ref: CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression. PMID: 10344733 |
Ref: Mitoxantrone mediates demethylation and reexpression of cyclin d2, estrogen receptor and 14.3.3sigma in breast cancer cells. PMID: 12878861 |
Ref: Use of DNA from human stools to detect aberrant CpG island methylation of genes implicated in colorectal cancer. PMID: 15342451 |
Ref: Gene-specific methylation and subsequent risk of colorectal adenomas among participants of the polyp prevention trial. PMID: 15894675 Ref: Methylation of the ESR1 CpG island in the colorectal mucosa is an 'all or nothing' process in healthy human colon, and is accelerated by dietary folate supplementation in the mouse. PMID: 16042580 |
Ref: Promoter methylation status of the MGMT, hMLH1, and CDKN2A/p16 genes in non-neoplastic mucosa of patients with and without colorectal adenomas. PMID: 16820927 |
Ref: Molecular portrait of cisplatin induced response in human testis cancer cell lines based on gene expression profiles. PMID: 17711579 |
Ref: Ligand-dependent interaction between estrogen receptor alpha and adenomatous polyposis coli. PMID: 18498351 Ref: Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa. PMID: 18542073 Ref: Epigenetic signatures of familial cancer are characteristic of tumor type and family category. PMID: 18559504 |
Ref: Methylation of estrogen receptor 1 in colorectal adenomas is not age-dependent, but is correlated with K-ras mutation. PMID: 19302287 Ref: An expression module of WIPF1-coexpressed genes identifies patients with favorable prognosis in three tumor types. PMID: 19399471 Ref: Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice. PMID: 19520794 Ref: Concordant DNA methylation in synchronous colorectal carcinomas. PMID: 19737982 Ref: DNA/RNA markers for colorectal cancer risk in preserved stool specimens: a pilot study. PMID: 20210241 |
Ref: Methylation status of normal background mucosa is correlated with occurrence and development of neoplasia in the distal colon. PMID: 19733896 Ref: Hormone therapy, DNA methylation and colon cancer. PMID: 20064828 Ref: Genetic variation in sex-steroid receptors and synthesizing enzymes and colorectal cancer risk in women. PMID: 20148360 Ref: Estrogen receptor alpha polymorphisms and the risk of malignancies. PMID: 20383761 Ref: Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas. PMID: 20572039 Ref: Epigenetic control of estrogen receptor expression and tumor suppressor genes is modulated by bioactive food compounds. PMID: 21088384 |
Ref: Significance of estrogen receptor 1 (ESR-1) gene imbalances in colon and hepatocellular carcinomas based on tissue microarrays analysis. PMID: 20458558 Ref: Association of genetic polymorphisms in ESR2, HSD17B1, ABCB1, and SHBG genes with colorectal cancer risk. PMID: 21317201 Ref: Methylation profiling of rectal cancer identifies novel markers of early-stage disease. PMID: 21360524 Ref: Phosphorylated AKT expression is associated with PIK3CA mutation, low stage, and favorable outcome in 717 colorectal cancers. PMID: 21425139 Ref: Modification of menopausal hormone therapy-associated colorectal cancer risk by polymorphisms in sex steroid signaling, metabolism and transport related genes. PMID: 21490239 Ref: Estrogen and progesterone-related gene variants and colorectal cancer risk in women. PMID: 21627810 |
Ref: Mutation and association analyses of the candidate genes ESR1, ESR2, MAX, PCNA, and KAT2A in patients with unexplained MSH2-deficient tumors. PMID: 22086303 Ref: Externalization of saw-tooth architecture in small serrated polyps implies the presence of methylation of IGFBP7. PMID: 22173745 Ref: Short-term folate supplementation in physiological doses has no effect on ESR1 and MLH1 methylation in colonic mucosa of individuals with adenoma. PMID: 23328702 |
Ref: Quantitative profiling of CpG island methylation in human stool for colorectal cancer detection. PMID: 22791128 Ref: Common single-nucleotide polymorphisms in the estrogen receptor beta promoter are associated with colorectal cancer survival in postmenopausal women. PMID: 23149914 Ref: Gene methylation in rectal cancer: predictive marker of response to chemoradiotherapy? PMID: 23702823 Ref: The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia. PMID: 24108782 Ref: BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production. PMID: 24322755 |
Ref: Demethylation effect of the antineoplaston AS2-1 on genes in colon cancer cells. PMID: 24213840 Ref: A network-based, integrative approach to identify genes with aberrant co-methylation in colorectal cancer. PMID: 24317156 Ref: Soy promotes juvenile granulosa cell tumor development in mice and in the human granulosa cell tumor-derived COV434 cell line. PMID: 25165122 |
Ref: Estrogen receptors and their implications in colorectal carcinogenesis. PMID: 25699240 Ref: Immune response gene expression in colorectal cancer carries distinct prognostic implications according to tissue, stage and site: a prospective retrospective translational study in the context of a hellenic cooperative oncology group randomised trial. PMID: 25970543 Ref: Screening of potential diagnostic markers and therapeutic targets against colorectal cancer. PMID: 26185457 Ref: Expression profiling of in vivo ductal carcinoma in situ progression models identified B cell lymphoma-9 as a molecular driver of breast cancer invasion. PMID: 26384318 Ref: Phytochemical Indicaxanthin Inhibits Colon Cancer Cell Growth and Affects the DNA Methylation Status by Influencing Epigenetically Modifying Enzyme Expression and Activity. PMID: 26439130 Ref: Molecular Features and Methylation Status in Early Onset ( PMID: 26557847 Ref: Aberrant DNA methylation profiles of inherited and sporadic colorectal cancer. PMID: 26697123 |
Ref: Promotor analysis of ESR1 in endometrial cancer cell lines, endometrial and endometriotic tissue. PMID: 28578502 Ref: Aberrantly methylated-differentially expressed genes and pathways in colorectal cancer. PMID: 28794688 Ref: Significance of intratissue estrogen concentration coupled with estrogen receptors levels in colorectal cancer prognosis. PMID: 29383180 |
Ref: Construction of key signal regulatory network in metastatic colorectal cancer. PMID: 29464057 Ref: Key genes and regulatory networks involved in the initiation, progression and invasion of colorectal cancer. PMID: 29568567 Ref: The Pancancer DNA Methylation Trackhub: A Window to The Cancer Genome Atlas Epigenomics Data. PMID: 29605850 |