Primary Site >> Pancreatic Cancer

Gene >> ERBB4

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Ref: Mechanisms of resistance to Erbitux (anti-epidermal growth factor receptor) combination therapy in pancreatic adenocarcinoma cells.
PMID: 15585383
Ref: [(11)C]N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine
PMID: 20641864
Ref: Tyrosine kinase inhibitors. 19. 6-Alkynamides of 4-anilinoquinazolines and 4-anilinopyrido[3,4-d]pyrimidines as irreversible inhibitors of the erbB family of tyrosine kinase receptors.
PMID: 16480284
Ref: Epidermal growth factor receptor regulates pancreatic fibrosis.
PMID: 19608732
Ref: Radiosensitization of epidermal growth factor receptor/HER2-positive pancreatic cancer is mediated by inhibition of Akt independent of ras mutational status.
PMID: 20103665
Ref: Ligand stimulation of ErbB4 and a constitutively-active ErbB4 mutant result in different biological responses in human pancreatic tumor cell lines.
PMID: 21110957
Ref: Targeting EGFR in pancreatic cancer treatment.
PMID: 22458527
Ref: Multiple Functional Motifs Are Required for the Tumor Suppressor Activity of a Constitutively-Active ErbB4 Mutant.
PMID: 24791013
Ref: The ErbB/HER family of protein-tyrosine kinases and cancer.
PMID: 24269963
Ref: A comprehensive review of the preclinical efficacy profile of the ErbB family blocker afatinib in cancer.
PMID: 24643470
Ref: The hepatitis B virus X protein promotes pancreatic cancer through modulation of the PI3K/AKT signaling pathway.
PMID: 27339327
Ref: The prognostic significance of human epidermal growth factor receptor family protein expression in operable pancreatic cancer : HER1-4 protein expression and prognosis in pancreatic cancer.
PMID: 27871278