Primary Site >> Liver Cancer

Gene >> EPHX1

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Ref: Immunochemical comparison of human and rhesus monkey liver microsomal and the hepatocellular carcinoma-induced human serum epoxide hydrolases (preneoplastic antigens): basis for an enzyme-linked immunoabsorbent assay.
PMID: 2536300
Ref: Biochemical and histochemical properties of hepatic tumors of rainbow trout, Oncorhynchus mykiss.
PMID: 8094646
Ref: Relationship between the microsomal epoxide hydrolase and the hepatocellular transport of bile acids and xenobiotics.
PMID: 7487959
Ref: Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1.
PMID: 7892276
Ref: Molecular and genetic epidemiology of hepatocellular carcinoma: studies in China and Senegal.
PMID: 8875609
Ref: Microsomal epoxide hydrolase polymorphism as a risk factor for ovarian cancer.
PMID: 8944076
Ref: Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
PMID: 10026993
Ref: Role of genetic polymorphism of glutathione-S-transferase T1 and microsomal epoxide hydrolase in aflatoxin-associated hepatocellular carcinoma.
PMID: 11440964
Ref: Polymorphisms of microsomal epoxide hydrolase gene and severity of HCV-related liver disease.
PMID: 12085365
Ref: A phylogenetic analysis identifies heterogeneity among hepatocellular carcinomas.
PMID: 12447857
Ref: Susceptibility to aflatoxin B1-related primary hepatocellular carcinoma in mice and humans.
PMID: 12907637
Ref: Determinants of the variability of aflatoxin-albumin adduct levels in Ghanaians.
PMID: 17162498
Ref: Meta-analysis of microsomal epoxide hydrolase gene polymorphism and risk of hepatocellular carcinoma.
PMID: 23451147
Ref: Lack of association of EPHX1 gene polymorphisms with risk of hepatocellular carcinoma: a meta-analysis.
PMID: 23955801
Ref: Hepatitis B spliced protein (HBSP) promotes the carcinogenic effects of benzo [alpha] pyrene by interacting with microsomal epoxide hydrolase and enhancing its hydrolysis activity.
PMID: 24758376
Ref: [EPHX1 Tyr113His polymorphism contributes to hepatocellular carcinoma risk: evidfnce from a meta-analysis].
PMID: 26065263
Ref: Altered cellular metabolism of HepG2 cells caused by microcystin-LR.
PMID: 28336091