Primary Site >> Esophagus Cancer
Gene >> EPHB2
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Ref: Overexpression of protein tyrosine kinases in human esophageal cancer. PMID: 9396043 |
Ref: Suppression of Erk activation and in vivo growth in esophageal cancer cells by the dominant negative Ras mutant, N116Y. PMID: 9766573 |
Ref: Constitutive ERK1/2 activation in esophagogastric rib bone marrow micrometastatic cells is MEK-independent. PMID: 11297525 Ref: Genistein, a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: possible involvement of inhibition of survival signal transduction pathways. PMID: 11316564 |
Ref: Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways. PMID: 14586407 |
Ref: The induction of prostaglandin E2 production, interleukin-6 production, cell cycle arrest, and cytotoxicity in primary oral keratinocytes and KB cancer cells by areca nut ingredients is differentially regulated by MEK/ERK activation. PMID: 15375172 |
Ref: Differentiation-associated genes regulated by TPA-induced c-Jun expression via a PKC/JNK pathway in KYSE450 cells. PMID: 16480952 Ref: Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients. PMID: 16575012 |
Ref: Neutrophil elastase induces cell proliferation and migration by the release of TGF-alpha, PDGF and VEGF in esophageal cell lines. PMID: 17143494 |
Ref: Epinephrine stimulates esophageal squamous-cell carcinoma cell proliferation via beta-adrenoceptor-dependent transactivation of extracellular signal-regulated kinase/cyclooxygenase-2 pathway. PMID: 18452159 Ref: Sorafenib inhibits MAPK-mediated proliferation in a Barrett's esophageal adenocarcinoma cell line. PMID: 18840136 Ref: Pilot study of gefitinib, oxaliplatin, and radiotherapy for esophageal adenocarcinoma: tissue effect predicts clinical response. PMID: 18845990 |
Ref: A novel pharmacodynamic approach to assess and predict tumor response to the epidermal growth factor receptor inhibitor gefitinib in patients with esophageal cancer. PMID: 19956829 Ref: shRNA interference for extracellular signal-regulated kinase 2 can inhibit the growth of esophageal cancer cell line Eca109. PMID: 20415541 |
Ref: The expression and activation of ERK/MAPK pathway in human esophageal cancer cell line EC9706. PMID: 20464500 Ref: A novel small molecule inhibitor of FAK and IGF-1R protein interactions decreases growth of human esophageal carcinoma. PMID: 21707510 Ref: BRAF mutations in advanced cancers: clinical characteristics and outcomes. PMID: 22039425 |
Ref: Lapatinib, a dual inhibitor of EGFR and HER2, has synergistic effects with 5-fluorouracil on esophageal carcinoma. PMID: 22293713 Ref: pERK activation in esophageal carcinomas: clinicopathological associations. PMID: 22658382 Ref: Esophageal cancer exhibits resistance to a novel IGF-1R inhibitor NVP-AEW541 with maintained RAS-MAPK activity. PMID: 22753744 Ref: Downregulation of tropomyosin-1 in squamous cell carcinoma of esophagus, the role of Ras signaling and methylation. PMID: 22965424 Ref: Rab25 is a tumor suppressor gene with antiangiogenic and anti-invasive activities in esophageal squamous cell carcinoma. PMID: 22991305 |
Ref: Antiproliferative effect of the HSP90 inhibitor NVP-AUY922 is determined by the expression of PTEN in esophageal cancer. PMID: 23064324 Ref: Survival after definitive (chemo)radiotherapy in esophageal cancer patients: a population-based study in the north-East Netherlands. PMID: 23274534 Ref: Oncogenic role of protein tyrosine kinase 7 in esophageal squamous cell carcinoma. PMID: 23663482 Ref: Survival in patients treated with definitive chemo- radiotherapy for non-metastatic esophageal cancer in north- west iran. PMID: 23679255 Ref: Differentiation of immature DCs into endothelial-like cells in human esophageal carcinoma tissue homogenates. PMID: 23708958 Ref: The radiation-sensitizing effect of flavopiridol in the esophageal cancer cell line Eca109. PMID: 23833659 Ref: Enhancement of (-)-epigallocatechin-3-gallate and theaflavin-3-3'-digallate induced apoptosis by ascorbic acid in human lung adenocarcinoma SPC-A-1 cells and esophageal carcinoma Eca-109 cells via MAPK pathways. PMID: 23892041 Ref: The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer. PMID: 24244023 |
Ref: Obatoclax induces G1/G0-phase arrest via p38/p21(waf1/Cip1) signaling pathway in human esophageal cancer cells. PMID: 24788582 Ref: Protein tyrosine kinase 7 plays a tumor suppressor role by inhibiting ERK and AKT phosphorylation in lung cancer. PMID: 24789704 Ref: RNA-seq reveals determinants of sensitivity to chemotherapy drugs in esophageal carcinoma cells. PMID: 24817948 Ref: DADS suppresses human esophageal xenograft tumors through RAF/MEK/ERK and mitochondria-dependent pathways. PMID: 25026173 Ref: Induction of autophagy counteracts the anticancer effect of cisplatin in human esophageal cancer cells with acquired drug resistance. PMID: 25236911 |
Ref: Targeting VEGFR1- and VEGFR2-expressing non-tumor cells is essential for esophageal cancer therapy. PMID: 25595897 Ref: Nimotuzumab abrogates acquired radioresistance of KYSE-150R esophageal cancer cells by inhibiting EGFR signaling and cellular DNA repair. PMID: 25750543 Ref: Marsdenia tenacissima extract induces G0/G1 cell cycle arrest in human esophageal carcinoma cells by inhibiting mitogen-activated protein kinase (MAPK) signaling pathway. PMID: 26073339 Ref: High EGFR and low p-Akt expression is associated with better outcome after nimotuzumab-containing treatment in esophageal cancer patients: preliminary clinical result and testable hypothesis. PMID: 26124180 Ref: IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma. PMID: 26317790 |
Ref: Griffipavixanthone, a dimeric xanthone extracted from edible plants, inhibits tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer. PMID: 26646323 Ref: [Effect of bufalin on proliferation and apoptosis through ERK/RSK2 pathway in human esophageal carcinoma cell line xenografts in nude mice]. PMID: 27188603 Ref: A Novel Role of Cab45-G in Mediating Cell Migration in Cancer Cells. PMID: 27194945 |
Ref: HER2 Confers Resistance to Foretinib Inhibition of MET-Amplified Esophageal Adenocarcinoma Cells. PMID: 29223420 Ref: Down-regulation of RIP3 potentiates cisplatin chemoresistance by triggering HSP90-ERK pathway mediated DNA repair in esophageal squamous cell carcinoma. PMID: 29331417 Ref: Cullin7 promotes epithelialmesenchymal transition of esophageal carcinoma via the ERKSNAI2 signaling pathway. PMID: 29393450 Ref: Progranulin promotes lymphangiogenesis through VEGF-C and is an independent risk factor in human esophageal cancers. PMID: 29452214 Ref: Super-Enhancer-Driven Long Non-Coding RNA LINC01503, Regulated by TP63, Is Over-Expressed and Oncogenic in Squamous Cell Carcinoma. PMID: 29454790 Ref: Glucose-regulated protein 94 mediates progression and metastasis of esophageal squamous cell carcinoma via mitochondrial function and the NF-kB/COX-2/VEGF axis. PMID: 29507700 Ref: Cystatin A suppresses tumor cell growth through inhibiting epithelial to mesenchymal transition in human lung cancer. PMID: 29581829 Ref: Chemoresistance to Cancer Treatment: Benzo-alpha-Pyrene as Friend or Foe? PMID: 29673198 Ref: Eupatilin inhibits the proliferation of human esophageal cancer TE1 cells by targeting the AktGSK3beta and MAPK/ERK signaling cascades. PMID: 29693162 Ref: IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment. PMID: 29976575 Ref: Quercetin-3-methyl ether inhibits esophageal carcinogenesis by targeting the AKT/mTOR/p70S6K and MAPK pathways. PMID: 30035335 Ref: Synephrine Hydrochloride Suppresses Esophageal Cancer Tumor Growth and Metastatic Potential through Inhibition of Galectin-3-AKT/ERK Signaling. PMID: 30113849 Ref: RUNX2 Plays An Oncogenic Role in Esophageal Carcinoma by Activating the PI3K/AKT and ERK Signaling Pathways. PMID: 30138923 Ref: The Curcumin Analogs 2-Pyridyl Cyclohexanone Induce Apoptosis via Inhibition of the JAK2-STAT3 Pathway in Human Esophageal Squamous Cell Carcinoma Cells. PMID: 30186159 Ref: The Role of Tumor Microenvironment in Chemoresistance: 3D Extracellular Matrices as Accomplices. PMID: 30241395 |