Primary Site >> Pancreatic Cancer
Gene >> EPCAM
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Ref: Molecular cloning of cDNA for the carcinoma-associated antigen GA733-2. PMID: 2333300 |
Ref: Immunogenicity of recombinant GA733-2E antigen (CO17-1A, EGP, KS1-4, KSA, Ep-CAM) in gastro-intestinal carcinoma patients. PMID: 11279610 |
Ref: Establishment of clonal colony-forming assay for propagation of pancreatic cancer cells with stem cell properties. PMID: 17446842 Ref: C4.4A as a candidate marker in the diagnosis of colorectal cancer. PMID: 17912244 |
Ref: Therapeutic window of MuS110, a single-chain antibody construct bispecific for murine EpCAM and murine CD3. PMID: 18172306 |
Ref: Claudin-7 regulates EpCAM-mediated functions in tumor progression. PMID: 19276185 Ref: Targeting of cancer stem cell marker EpCAM by bispecific antibody EpCAMxCD3 inhibits pancreatic carcinoma. PMID: 20196789 |
Ref: Identification of a novel putative pancreatic stem/progenitor cell marker DCAMKL-1 in normal mouse pancreas. PMID: 20522640 |
Ref: Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study. PMID: 21145788 Ref: Immunotherapy of peritoneal carcinomatosis with the antibody catumaxomab in colon, gastric, or pancreatic cancer: an open-label, multicenter, phase I/II trial. PMID: 21358214 Ref: Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer. PMID: 21408027 Ref: Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells. PMID: 21463919 Ref: Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells. PMID: 21503965 |
Ref: Metformin inhibits cell proliferation, migration and invasion by attenuating CSC function mediated by deregulating miRNAs in pancreatic cancer cells. PMID: 22086681 Ref: EpCAM/CD3-Bispecific T-cell engaging antibody MT110 eliminates primary human pancreatic cancer stem cells. PMID: 22096026 Ref: Curcumin analogue CDF inhibits pancreatic tumor growth by switching on suppressor microRNAs and attenuating EZH2 expression. PMID: 22108826 Ref: New gene-immunotherapy combining TRAIL-lymphocytes and EpCAMxCD3 Bispecific antibody for tumor targeting. PMID: 22228630 Ref: Multimarker gene analysis of circulating tumor cells in pancreatic cancer patients: a feasibility study. PMID: 22270149 Ref: Label-free reflectometric interference microchip biosensor based on nanoporous alumina for detection of circulating tumour cells. PMID: 22429961 Ref: Therapeutic potential of amanitin-conjugated anti-epithelial cell adhesion molecule monoclonal antibody against pancreatic carcinoma. PMID: 22457476 Ref: Adamantyl Retinoid-Related Molecules Induce Apoptosis in Pancreatic Cancer Cells by Inhibiting IGF-1R and Wnt/beta-Catenin Pathways. PMID: 22570653 Ref: High interstitial fluid pressure is associated with low tumour penetration of diagnostic monoclonal antibodies applied for molecular imaging purposes. PMID: 22590529 Ref: Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition. PMID: 22591372 Ref: Nestin and other putative cancer stem cell markers in pancreatic cancer. PMID: 22718289 Ref: Immuno-targeting of pancreatic cancer stem cells: A new therapeutic strategy against a devastating disease? PMID: 22754787 Ref: Comparative testing of various pancreatic cancer stem cells results in a novel class of pancreatic-cancer-initiating cells. PMID: 22963768 Ref: Pancreatic cancer cells surviving gemcitabine treatment express markers of stem cell differentiation and epithelial-mesenchymal transition. PMID: 23026911 Ref: Epithelial mesenchymal transition and pancreatic tumor initiating CD44+/EpCAM+ cells are inhibited by gamma-secretase inhibitor IX. PMID: 23094026 |
Ref: Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype. PMID: 22806240 Ref: EpCAM-associated claudin-7 supports lymphatic spread and drug resistance in rat pancreatic cancer. PMID: 23390083 Ref: Isolation of rare tumor cells from blood cells with buoyant immuno-microbubbles. PMID: 23516425 Ref: Epithelial cell adhesion molecule (EpCAM) overexpression is correlated with malignant potentials of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. PMID: 23594482 Ref: Histological and prognostic importance of CD44(+) /CD24(+) /EpCAM(+) expression in clinical pancreatic cancer. PMID: 23679813 Ref: Modular microsystem for the isolation, enumeration, and phenotyping of circulating tumor cells in patients with pancreatic cancer. PMID: 23947293 Ref: CD24+/CD38- as new prognostic marker for non-small cell lung cancer. PMID: 24094028 Ref: Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling. PMID: 24466367 |
Ref: Loss of membranous expression of the intracellular domain of EpCAM is a frequent event and predicts poor survival in patients with pancreatic cancer. PMID: 24117877 Ref: Micropallet arrays for the capture, isolation and culture of circulating tumor cells from whole blood of mice engrafted with primary human pancreatic adenocarcinoma. PMID: 24316450 Ref: Analysis of the tumor-initiating and metastatic capacity of PDX1-positive cells from the adult pancreas. PMID: 24550494 Ref: Microfluidic immunocapture of circulating pancreatic cells using parallel EpCAM and MUC1 capture: characterization, optimization and downstream analysis. PMID: 24681997 Ref: Pancreatic cancer stem-like cells display aggressive behavior mediated via activation of FoxQ1. PMID: 24719318 Ref: Differentially expressed miRNAs in cancer-stem-like cells: markers for tumor cell aggressiveness of pancreatic cancer. PMID: 24734907 Ref: An epithelial cell adhesion molecule- and CD3-bispecific antibody plus activated T-cells can eradicate chemoresistant cancer stem-like pancreatic carcinoma cells in vitro. PMID: 25075094 Ref: Serum EpCAM expression in pancreatic cancer. PMID: 25202052 Ref: Immunohistochemical analysis of cancer stem cell markers in pancreatic adenocarcinoma patients after neoadjuvant chemoradiotherapy. PMID: 25240521 Ref: Characterization of microfluidic shear-dependent epithelial cell adhesion molecule immunocapture and enrichment of pancreatic cancer cells from blood cells with dielectrophoresis. PMID: 25379092 |
Ref: Combined evaluation of a panel of protein and miRNA serum-exosome biomarkers for pancreatic cancer diagnosis increases sensitivity and specificity. PMID: 25388097 Ref: Targeting cancer stem cells in solid tumors by vitamin D. PMID: 25460302 Ref: Efficacy of irreversible electroporation in human pancreatic adenocarcinoma: advanced murine model. PMID: 26029712 Ref: Hyaluronic Acid Engineered Nanomicelles Loaded with 3,4-Difluorobenzylidene Curcumin for Targeted Killing of CD44+ Stem-Like Pancreatic Cancer Cells. PMID: 26302089 Ref: Quantitative assessment of the cell surface proteome to identify novel therapeutic targets in cholangiocarcinoma. PMID: 26312917 Ref: An anti-EpCAM antibody EpAb2-6 for the treatment of colon cancer. PMID: 26317650 Ref: Cantharidin and norcantharidin impair stemness of pancreatic cancer cells by repressing the beta-catenin pathway and strengthen the cytotoxicity of gemcitabine and erlotinib. PMID: 26398277 Ref: Cytoplasmic EpCAM over-expression is associated with favorable clinical outcomes in pancreatic cancer patients with Hepatitis B virus negative infection. PMID: 26885196 |
Ref: p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling. PMID: 26546043 Ref: Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells. PMID: 26673007 Ref: Hypoxic Conditions Promote Gemcitabine Sensitivity in a Pancreatic Cancer Stem Cell Line. PMID: 26851020 Ref: Tumour-associated circulating microparticles: A novel liquid biopsy tool for screening and therapy monitoring of colorectal carcinoma and other epithelial neoplasia. PMID: 27127176 Ref: Pancreatic cancer stem cells in patient pancreatic xenografts are sensitive to drozitumab, an agonistic antibody against DR5. PMID: 27330806 Ref: Pancreatic cancer stem cell markers and exosomes - the incentive push. PMID: 27468191 |
Ref: Establishment and characterization of a new human acinar cell carcinoma cell line, Faraz-ICR, from pancreas. PMID: 28215484 Ref: Cancer-associated circulating large extracellular vesicles in cholangiocarcinoma and hepatocellular carcinoma. PMID: 28267620 Ref: Microfluidic continuum sorting of sub-populations of tumor cells via surface antibody expression levels. PMID: 28294230 Ref: Doublecortin and CaM kinase-like-1 as an independent prognostic factor in patients with resected pancreatic carcinoma. PMID: 28883702 Ref: Isolation of circulating tumor cells from pancreatic cancer by automated filtration. PMID: 29156783 Ref: Fibrin-bearing microparticles: marker of thrombo-embolic events in pancreatic and colorectal cancers. PMID: 29228619 |
Ref: Improved Detection of Circulating Epithelial Cells in Patients with Intraductal Papillary Mucinous Neoplasms. PMID: 28860411 Ref: Using circulating tumor cells to evaluate the efficacy of irreversible electroporation for unresectasble pancreatic cancer. PMID: 29143247 Ref: Luteolin inhibits pancreatitisinduced acinarductal metaplasia, proliferation and epithelialmesenchymal transition of acinar cells. PMID: 29286098 Ref: Improved Risk Stratification by Circulating Tumor Cell Counts in Pancreatic Cancer. PMID: 29559560 Ref: MEKK3 Sustains EMT and Stemness in Pancreatic Cancer by Regulating YAP and TAZ Transcriptional Activity. PMID: 29599309 Ref: Bitter melon juice exerts its efficacy against pancreatic cancer via targeting both bulk and cancer stem cells. PMID: 29727019 Ref: Immunomagnetic Lipid Separation and Plastin Identification for Pancreatic Cancer Cells and Its Clinical Application. PMID: 29843873 Ref: MicroRNA-30b targets Snail to impede epithelial-mesenchymal transition in pancreatic cancer stem cells. PMID: 29937934 Ref: Extract of the Medicinal Plant Pao Pereira Inhibits Pancreatic Cancer Stem-Like Cell In Vitro and In Vivo. PMID: 29985062 Ref: Solid-pseudopapillary neoplasms of the pancreas do not express major pancreatic markers in pediatric patients. PMID: 30130629 |