Primary Site >> Colorectal Cancer
Gene >> EPCAM
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Ref: Characterization of Lewis antigens in normal colon and gastrointestinal adenocarcinomas. PMID: 2582419 |
Ref: Epithelium-specific surface glycoprotein of Mr 34,000 is a widely distributed human carcinoma marker. PMID: 2449234 Ref: A sandwich enzyme immunoassay of an adenocarcinoma-associated antigen, YH206, in cancer sera. PMID: 3038813 Ref: [Analysis of tumor-associated antigen of the digestive tract by monoclonal antibody]. PMID: 3606145 |
Ref: Biochemical analysis of a human epithelial surface antigen: differential cell expression and processing. PMID: 3196032 |
Ref: Molecular cloning of cDNA for the carcinoma-associated antigen GA733-2. PMID: 2333300 |
Ref: Lynch Syndrome PMID: 20301390 |
Ref: New chimeric anti-pancarcinoma monoclonal antibody with superior cytotoxicity-mediating potency. PMID: 8137290 |
Ref: Human anti-idiotypic antibodies induced a humoral and cellular immune response against a colorectal carcinoma-associated antigen in patients. PMID: 7539133 |
Ref: Biologic properties of a bispecific single-chain antibody directed against 17-1A (EpCAM) and CD3: tumor cell-dependent T cell stimulation and cytotoxic activity. PMID: 9103467 |
Ref: High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting. PMID: 9836471 Ref: Immunohistochemical localization of epithelial glycoprotein EGP-2 and carcinoembryonic antigen in normal colonic mucosa and colorectal tumors. PMID: 9854475 Ref: Epithelial glycoprotein-2 expression is subject to regulatory processes in epithelial-mesenchymal transitions during metastases: an investigation of human cancers transplanted into severe combined immunodeficient mice. PMID: 9873999 |
Ref: Vicia faba agglutinin, the lectin present in broad beans, stimulates differentiation of undifferentiated colon cancer cells. PMID: 10205210 Ref: Detection of surface antigen 17-1A in breast and colorectal cancer. PMID: 10211786 Ref: Tumor-specific gene transfer via an adenoviral vector targeted to the pan-carcinoma antigen EpCAM. PMID: 10467371 Ref: Two proteins share immunological epitopes on the tumor-associated antigen 17-1A. PMID: 10503883 Ref: The biology of the 17-1A antigen (Ep-CAM). PMID: 10606205 Ref: Monoclonal antibody therapy with edrecolomab in breast cancer patients: monitoring of elimination of disseminated cytokeratin-positive tumor cells in bone marrow. PMID: 10632331 |
Ref: Specific targeting of EGP-2+ tumor cells by primary lymphocytes modified with chimeric T cell receptors. PMID: 10646635 Ref: Recognition of human colon cancer by T cells transduced with a chimeric receptor gene. PMID: 10770638 Ref: Cancer vaccines: single-epitope anti-idiotype vaccine versus multiple-epitope antigen vaccine. PMID: 10881691 Ref: Colorectal cancer vaccines: antiidiotypic antibody, recombinant protein, and viral vector. PMID: 10911917 Ref: Ga733/EpCAM as a target for passive and active specific immunotherapy in patients with colorectal carcinoma. PMID: 10911918 Ref: Augmentation of 17-1A-induced antibody-dependent cellular cytotoxicity by the triple cytokine combination of interferon-alpha, interleukin-2, and interleukin-12. PMID: 10916758 Ref: Prestimulation of monocytes by the cytokines GM-CSF or IL-2 enhances the antibody dependent cellular cytotoxicity of monoclonal antibody 17-1A. PMID: 11031784 Ref: Ep-CAM overexpression in breast cancer as a predictor of survival. PMID: 11130529 Ref: Technology evaluation: edrecolomab, Centocor Inc. PMID: 11249762 |
Ref: Oligomeric state of the colon carcinoma-associated glycoprotein GA733-2 (Ep-CAM/EGP40) and its role in GA733-mediated homotypic cell-cell adhesion. PMID: 11058587 Ref: Influence of cytokines, monoclonal antibodies and chemotherapeutic drugs on epithelial cell adhesion molecule (EpCAM) and LewisY antigen expression. PMID: 11167991 Ref: The level of MHC class I expression on murine adenocarcinoma can change the antitumor effector mechanism of immunocytokine therapy. PMID: 11245457 Ref: Identification of colon tumour-associated antigens by phage antibody selections on primary colorectal carcinoma. PMID: 11267865 Ref: Update of clinical trials with edrecolomab: a monoclonal antibody therapy for colorectal cancer. PMID: 11273586 Ref: Immunogenicity of recombinant GA733-2E antigen (CO17-1A, EGP, KS1-4, KSA, Ep-CAM) in gastro-intestinal carcinoma patients. PMID: 11279610 Ref: Protective immunity against human carcinoembryonic antigen (CEA) induced by an oral DNA vaccine in CEA-transgenic mice. PMID: 11300483 Ref: Preclinical evaluation of a humanized NR-LU-10 antibody-streptavidin fusion protein for pretargeted cancer therapy. PMID: 11385958 Ref: Anti-idiotypic antibody and recombinant antigen vaccines in colorectal cancer patients. PMID: 11418307 Ref: Anti-self antibodies selected from a human IgD heavy chain repertoire: a novel approach to generate therapeutic human antibodies against tumor-associated differentiation antigens. PMID: 11419181 Ref: Minimal costimulatory requirements for T cell priming and TH1 differentiation: activation of naive human T lymphocytes by tumor cells armed with bifunctional antibody constructs. PMID: 12747771 |
Ref: Enhancement of the complement activating capacity of 17-1A mAb to overcome the effect of membrane-bound complement regulatory proteins on colorectal carcinoma. PMID: 11754353 Ref: Inhibition of tumor growth by recombinant vaccinia virus expressing GA733/CO17-1A/EpCAM/KSA/KS1-4 antigen in mice. PMID: 11960289 Ref: MAb17-1A and cytokines for the treatment of patients with colorectal carcinoma. PMID: 12031098 Ref: Antigenic and immunologic characterization of an allogeneic colon carcinoma vaccine. PMID: 12100028 Ref: In vitro and in vivo activity of MT201, a fully human monoclonal antibody for pancarcinoma treatment. PMID: 12115595 Ref: Secreted and tumour targeted human carboxylesterase for activation of irinotecan. PMID: 12237777 |
Ref: Effect of surgical trauma on epithelial cell adhesion molecule (GA-733) vaccine-induced tumor resistance. PMID: 12457219 Ref: Efficient tumor cell lysis by autologous, tumor-resident T lymphocytes in primary ovarian cancer samples by an EP-CAM-/CD3-bispecific antibody. PMID: 12673686 Ref: Immunization of colorectal carcinoma patients with a recombinant canarypox virus expressing the tumor antigen Ep-CAM/KSA (ALVAC-KSA) and granulocyte macrophage colony- stimulating factor induced a tumor-specific cellular immune response. PMID: 12855617 Ref: Human tumor-derived heat shock protein 96 mediates in vitro activation and in vivo expansion of melanoma- and colon carcinoma-specific T cells. PMID: 14500642 Ref: EpCAM: A new therapeutic target for an old cancer antigen. PMID: 14508099 Ref: Naturally occurring antibodies to epithelial cell adhesion molecule (EpCAM). PMID: 14714617 |
Ref: Anticancer drug response and expression of molecular markers in early-passage xenotransplanted colon carcinomas. PMID: 14728946 Ref: Immunization of colorectal cancer patients with recombinant baculovirus-derived KSA (Ep-CAM) formulated with monophosphoryl lipid A in liposomal emulsion, with and without granulocyte-macrophage colony-stimulating factor. PMID: 14741172 Ref: Anti-EpCAM monoclonal antibody (MAb17-1A) based treatment combined with alpha-interferon, 5-fluorouracil and granulocyte-macrophage colony-stimulating factor in patients with metastatic colorectal carcinoma. PMID: 15289873 Ref: Vaccination with Ep-CAM protein or anti-idiotypic antibody induces Th1-biased response against MHC class I- and II-restricted Ep-CAM epitopes in colorectal carcinoma patients. PMID: 15328177 Ref: Search for epithelial-specific mRNAs in peripheral blood of patients with colon cancer by RT-PCR. PMID: 15375555 Ref: A new source of hepatocytes for transplantation. PMID: 15561283 |
Ref: T-cell receptor BV gene usage in colorectal carcinoma patients immunised with recombinant Ep-CAM protein or anti-idiotypic antibody. PMID: 15570423 Ref: T cell responses against tumor associated antigens and prognosis in colorectal cancer patients. PMID: 15659244 Ref: Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11. PMID: 15756257 Ref: Inhibition of tumor growth by plant-derived mAb. PMID: 15867145 Ref: Clinical effects of a chimeric anti-EpCAM monoclonal antibody in combination with granulocyte-macrophage colony-stimulating factor in patients with metastatic colorectal carcinoma. PMID: 15870873 Ref: Towards therapeutic vaccines for colorectal carcinoma: a review of clinical trials. PMID: 16026248 |
Ref: Serum antibodies to EpCAM in healthy donors but not ulcerative colitis patients. PMID: 16034560 Ref: MT110: a novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors. PMID: 16139892 Ref: Frequent high-level expression of the immunotherapeutic target Ep-CAM in colon, stomach, prostate and lung cancers. PMID: 16404366 Ref: Profiling of the tetraspanin web of human colon cancer cells. PMID: 16467180 Ref: Multiplex detection of surface molecules on colorectal cancers. PMID: 16485257 Ref: Identification of mRNA markers for molecular staging of lymph nodes in colorectal cancer. PMID: 16510433 Ref: Cross-linking tumor cells with effector cells via CD55 with a bispecific mAb induces beta-glucan-dependent CR3-dependent cellular cytotoxicity. PMID: 16525993 Ref: Genetic vaccines against Ep-CAM break tolerance to self in a limited subset of subjects: initial identification of predictive biomarkers. PMID: 16619291 Ref: Isolation and characterization of circulating tumor cells in patients with metastatic colorectal cancer. PMID: 16945168 |
Ref: EpCAM an immunotherapeutic target for gastrointestinal malignancy: current experience and future challenges. PMID: 17325709 Ref: Phenotypic characterization of human colorectal cancer stem cells. PMID: 17548814 Ref: A complex of EpCAM, claudin-7, CD44 variant isoforms, and tetraspanins promotes colorectal cancer progression. PMID: 17579117 Ref: Biodistribution studies of epithelial cell adhesion molecule (EpCAM)-directed monoclonal antibodies in the EpCAM-transgenic mouse tumor model. PMID: 17617629 Ref: Pharmacokinetic and safety study of subcutaneously administered weekly ING-1, a human engineere monoclonal antibody targeting human EpCAM, in patients with advanced solid tumors. PMID: 17693421 Ref: C4.4A as a candidate marker in the diagnosis of colorectal cancer. PMID: 17912244 Ref: Isolation of rare circulating tumour cells in cancer patients by microchip technology. PMID: 18097410 |
Ref: Plant-derived EpCAM antigen induces protective anti-cancer response. PMID: 17634938 Ref: Establishment and characterization of a new cell line derived from human colorectal laterally spreading tumor. PMID: 18300345 Ref: Detection of metastatic colon cancer cells in sentinel nodes by flow cytometry. PMID: 18377923 Ref: CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors. PMID: 18497886 Ref: CD133 expression is an independent prognostic marker for low survival in colorectal cancer. PMID: 18781171 Ref: CpG island methylation status in the EpCAM promoter region and gene expression. PMID: 18949402 Ref: Improved recovery of exfoliated colonocytes from feces using newly developed immunomagnetic beads. PMID: 19125182 |
Ref: Nuclear signalling by tumour-associated antigen EpCAM. PMID: 19136966 Ref: Transcriptional repression of epithelial cell adhesion molecule contributes to p53 control of breast cancer invasion. PMID: 19141643 Ref: EpCAM, a human tumor-associated antigen promotes Th2 development and tumor immune evasion. PMID: 19188665 Ref: Combination of aging and dimethylhydrazine treatment causes an increase in cancer-stem cell population of rat colonic crypts. PMID: 19465005 Ref: The emerging role of EpCAM in cancer and stem cell signaling. PMID: 19584271 |
Ref: Proteomics analysis of A33 immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature. PMID: 19837982 Ref: EpCAM: a potential antimetastatic target for gastric cancer. PMID: 19941073 Ref: Letter to the editor: efficacy and safety of anti-Trop antibodies, R. Cubas, M. Li, C. Chen and Q. Yao, Biochim Biophys Acta 1796 (2009) 309-1. PMID: 20079406 Ref: ABCG5-positivity in tumor buds is an indicator of poor prognosis in node-negative colorectal cancer patients. PMID: 20135722 Ref: In situ protein expression in tumour spheres: development of an immunostaining protocol for confocal microscopy. PMID: 20307308 Ref: Heterogeneous detection of circulating tumor cells in patients with colorectal cancer by immunomagnetic enrichment using different EpCAM-specific antibodies. PMID: 20426872 Ref: The EpCAM high/CD44 high colorectal carcinoma stem cell phenotype is not preferentially expressed in tumour buds. PMID: 20459564 Ref: [Detection of hepatic micrometastases in the context of adjuvant chemotherapy and surgery for hepatic metastases]. PMID: 20486059 Ref: Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer. PMID: 20606680 Ref: The Wnt/beta-catenin pathway regulates growth and maintenance of colonospheres. PMID: 20691072 Ref: FcgammaR polymorphisms and clinical outcome in colorectal cancer patients receiving passive or active antibody treatment. PMID: 21042730 |
Ref: Intrahepatically transplanted human cord blood cells reduce SW480 tumor growth in the presence of bispecific EpCAM/CD3 antibody. PMID: 20839999 Ref: L1-mediated colon cancer cell metastasis does not require changes in EMT and cancer stem cell markers. PMID: 21123622 Ref: Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study. PMID: 21145788 Ref: Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases. PMID: 21227399 Ref: High-throughput selection, enumeration, electrokinetic manipulation, and molecular profiling of low-abundance circulating tumor cells using a microfluidic system. PMID: 21319808 Ref: A gene signature distinguishing CD133hi from CD133- colorectal cancer cells: essential role for EGR1 and downstream factors. PMID: 21436631 Ref: Disseminated tumour cells as a prognostic biomarker in colorectal cancer. PMID: 21448171 Ref: Mesenchymal stem cells promote formation of colorectal tumors in mice. PMID: 21699785 Ref: Lynch syndrome-associated extracolonic tumors are rare in two extended families with the same EPCAM deletion. PMID: 21769135 Ref: Common cancer stem cell gene variants predict colon cancer recurrence. PMID: 21918173 Ref: Colorectal cancer cell surface protein profiling using an antibody microarray and fluorescence multiplexing. PMID: 21968569 Ref: Relationship between ganglioside expression and anti-cancer effects of the monoclonal antibody against epithelial cell adhesion molecule in colon cancer. PMID: 22033101 Ref: A novel platform for detection of CK+ and CK- CTCs. PMID: 22180853 |
Ref: Epithelial cell adhesion molecule expression (CD326) in cancer: a short review. PMID: 21576002 Ref: Effect of EpCAM, CD44, CD133 and CD166 expression on patient survival in tumours of the ampulla of Vater. PMID: 22130902 Ref: Cancer stem cell sorting from colorectal cancer cell lines by sedimentation field flow fractionation. PMID: 22236375 Ref: Free peritoneal tumor cells detection in gastric and colorectal cancer patients. PMID: 22258756 Ref: Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. PMID: 22285593 Ref: Detection of circulating tumor-associated antigen depends on the domains recognized by the monoclonal antibodies used: N-terminal trimmed EpCAM-levels are much higher than untrimmed forms. PMID: 22387297 Ref: Cellular apoptosis susceptibility (chromosome segregation 1-like, CSE1L) gene is a key regulator of apoptosis, migration and invasion in colorectal cancer. PMID: 22450763 Ref: Anti-epithelial cell adhesion molecule monoclonal antibody conjugated fluorescent nanoparticle biosensor for sensitive detection of colon cancer cells. PMID: 22464249 Ref: Prevalence of mismatch repair-deficient crypt foci in Lynch syndrome: a pathological study. PMID: 22552011 Ref: Downregulation of Prominin 1/CD133 expression in colorectal cancer by NSAIDs following short-term preoperative treatment. PMID: 22552364 Ref: High interstitial fluid pressure is associated with low tumour penetration of diagnostic monoclonal antibodies applied for molecular imaging purposes. PMID: 22590529 Ref: ColoSeq provides comprehensive lynch and polyposis syndrome mutational analysis using massively parallel sequencing. PMID: 22658618 Ref: A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers. PMID: 22670157 Ref: CD24 can be used to isolate Lgr5+ putative colonic epithelial stem cells in mice. PMID: 22723265 Ref: Apoptosis inhibitor 5 (API-5; AAC-11; FIF) is upregulated in human carcinomas in vivo. PMID: 22741017 Ref: Evaluation of carcinoembryonic antigen (CEA), epidermal growth factor receptor (EGFR), epithelial cell adhesion molecule EpCAM (GA733-2), and carbohydrate antigen 19-9 (CA 19-9) levels in colorectal cancer patients and correlation with clinicopathological PMID: 22783573 Ref: Molecular characterization of circulating tumor cells in human metastatic colorectal cancer. PMID: 22811761 Ref: MiR-214 targets beta-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma. PMID: 22962603 Ref: Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells. PMID: 22969042 Ref: Epithelial cell adhesion molecule regulates tumor initiation and tumorigenesis via activating reprogramming factors and epithelial-mesenchymal transition gene expression in colon cancer. PMID: 22989882 Ref: Challenges in the enumeration and phenotyping of CTC. PMID: 23014524 Ref: Prognostic and predictive value of circulating tumor cell analysis in colorectal cancer patients. PMID: 23146106 Ref: Establishment, characterization and chemosensitivity of three mismatch repair deficient cell lines from sporadic and inherited colorectal carcinomas. PMID: 23300683 |
Ref: Transcriptional profiling identifies genes induced by hepatocyte-derived extracellular matrix in metastatic human colorectal cancer cell lines. PMID: 22930170 Ref: Usefulness of epithelial cell adhesion molecule expression in the algorithmic approach to Lynch syndrome identification. PMID: 23026194 Ref: Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. PMID: 23230278 Ref: EPCAM deletion carriers constitute a unique subgroup of Lynch syndrome patients. PMID: 23264089 Ref: [A novel genetic disorder of Lynch syndrome - EPCAM gene deletion]. PMID: 23411950 Ref: A negative selection system PowerMag for effective leukocyte depletion and enhanced detection of EpCAM positive and negative circulating tumor cells. PMID: 23415697 Ref: Colorectal cancer in a 9-year-old due to combined EPCAM and MSH2 germline mutations: case report of a unique genotype and immunophenotype. PMID: 23454724 Ref: Epithelial cell adhesion molecule (EpCAM) regulates claudin dynamics and tight junctions. PMID: 23486470 Ref: A novel therapeutic drug for colon cancer: EpCAM scFv-truncated protamine (tp)-siRNA. PMID: 23576466 Ref: Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components. PMID: 23585443 Ref: Antibody conjugated supported lipid bilayer for capturing and purification of viable tumor cells in blood for subsequent cell culture. PMID: 23615560 Ref: High-level microsatellite instability in appendiceal carcinomas. PMID: 23648460 Ref: Capture of viable circulating tumor cells in the liver of colorectal cancer patients. PMID: 23695297 Ref: EPCAM germline and somatic rearrangements in Lynch syndrome: identification of a novel 3'EPCAM deletion. PMID: 23801599 Ref: Postoperative detection of circulating tumor cells predicts tumor recurrence in colorectal cancer patients. PMID: 23813048 Ref: Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a PIK3CA Mutation. PMID: 23826249 Ref: Omega-3 eicosapentaenoic acid decreases CD133 colon cancer stem-like cell marker expression while increasing sensitivity to chemotherapy. PMID: 23874993 Ref: Murine portal vein catheterization to analyze liver-directed therapies. PMID: 23890402 Ref: Germline deletions in the EPCAM gene as a cause of Lynch syndrome - literature review. PMID: 23938213 Ref: High-performance size-based microdevice for the detection of circulating tumor cells from peripheral blood in rectal cancer patients. PMID: 24066187 Ref: Plant-derived mAbs have effective anti-cancer activities by increasing ganglioside expression in colon cancers. PMID: 24078119 Ref: The advantage of circulating tumor cells over serum carcinoembryonic antigen for predicting treatment responses in rectal cancer. PMID: 24106900 Ref: Engineered nanopore of Phi29 DNA-packaging motor for real-time detection of single colon cancer specific antibody in serum. PMID: 24152066 Ref: Circulating tumor cells are associated with diffuse spread in stage IV colorectal cancer patients. PMID: 24153154 Ref: Efficacy and feasibility of the epithelial cell adhesion molecule (EpCAM) immunomagnetic cell sorter for studies of DNA methylation in colorectal cancer. PMID: 24362576 Ref: Systemic effect of catumaxomab in a patient with metastasized colorectal cancer: a case report. PMID: 24380380 |
Ref: History, genetics, and strategies for cancer prevention in Lynch syndrome. PMID: 23891921 Ref: Inversion of exons 1-7 of the MSH2 gene is a frequent cause of unexplained Lynch syndrome in one local population. PMID: 24114314 Ref: Cancer-initiating cells from colorectal cancer patients escape from T cell-mediated immunosurveillance in vitro through membrane-bound IL-4. PMID: 24277698 Ref: Multicolor detection of rare tumor cells in blood using a novel flow cytometry-based system. PMID: 24327318 Ref: Raloxifene and antiestrogenic gonadorelin inhibits intestinal tumorigenesis by modulating immune cells and decreasing stem-like cells. PMID: 24431404 Ref: Decreased miR-340 expression in bone marrow is associated with liver metastasis of colorectal cancer. PMID: 24448820 Ref: Optimization of ELISA conditions to quantify colorectal cancer antigen-antibody complex protein (GA733-FcK) expressed in transgenic plant. PMID: 24555929 Ref: Treatment of gastric peritoneal carcinomatosis by combining complete surgical resection of lesions and intraperitoneal immunotherapy using catumaxomab. PMID: 24589307 Ref: Epithelial cell adhesion molecule aptamer functionalized PLGA-lecithin-curcumin-PEG nanoparticles for targeted drug delivery to human colorectal adenocarcinoma cells. PMID: 24591829 Ref: Highly sensitive detection of cancer cells based on the DNA barcode assay and microcapillary electrophoretic analysis. PMID: 24615960 Ref: Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma. PMID: 24621249 Ref: [Cell morphology in the dormancy and proliferation stage of colorectal cancer stem cells]. PMID: 24671820 Ref: Interleukin-17A modulates circulating tumor cells in tumor draining vein of colorectal cancers and affects metastases. PMID: 24677375 Ref: P21 and CD166 as predictive markers of poor response and outcome after fluorouracil-based chemoradiotherapy for the patients with rectal cancer. PMID: 24708484 Ref: Expression and clinical significance of colorectal cancer stem cell marker EpCAM(high)/CD44(+) in colorectal cancer. PMID: 24765173 Ref: Clinical prognostic value of combined analysis of Aldh1, Survivin, and EpCAM expression in colorectal cancer. PMID: 24786601 Ref: Colorectal carcinomas in 2013: the search for powerful prognostic markers is still on the go! PMID: 24878815 Ref: Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells. PMID: 24921652 Ref: Small sample sorting of primary adherent cells by automated micropallet imaging and release. PMID: 24939722 Ref: Lynch syndrome: an updated review. PMID: 24978665 Ref: The mutational spectrum of Lynch syndrome in cyprus. PMID: 25133505 Ref: A novel detection strategy for living circulating tumor cells using 5-aminolevulinic acid. PMID: 25218346 Ref: Deep sequencing of RNA from three different extracellular vesicle (EV) subtypes released from the human LIM1863 colon cancer cell line uncovers distinct miRNA-enrichment signatures. PMID: 25330373 Ref: Comparison of putative circulating cancer stem cell detection between the hepatic portal system and peripheral blood in colorectal cancer patients. PMID: 25368848 Ref: Growth suppression of colorectal cancer by plant-derived multiple mAb CO17-1A x BR55 via inhibition of ERK1/2 phosphorylation. PMID: 25405740 Ref: ABCG2-meditated multidrug resistance and tumor-initiating capacity of side population cells from colon cancer. PMID: 25427584 Ref: Stem cells, colorectal cancer and cancer stem cell markers correlations. PMID: 25729599 |
Ref: Lynch-like syndrome: characterization and comparison with EPCAM deletion carriers. PMID: 25110875 Ref: MLH1 promotor hypermethylation does not rule out a diagnosis of Lynch syndrome: a case report. PMID: 25213678 Ref: Selective bispecific T cell recruiting antibody and antitumor activity of adoptive T cell transfer. PMID: 25424197 Ref: Cell-surface Vimentin: A mislocalized protein for isolating csVimentin(+) CD133(-) novel stem-like hepatocellular carcinoma cells expressing EMT markers. PMID: 25487874 Ref: Claudin-7 promotes the epithelial-mesenchymal transition in human colorectal cancer. PMID: 25514462 Ref: Using DNA aptamer probe for immunostaining of cancer frozen tissues. PMID: 25536018 Ref: Establishment and characterization of cell lines from chromosomal instable colorectal cancer. PMID: 25574089 Ref: Exploring cancer metastasis prevention strategy: interrupting adhesion of cancer cells to vascular endothelia of potential metastatic tissues by antibody-coated nanomaterial. PMID: 25643843 Ref: Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer. PMID: 25652097 Ref: Characterization and propagation of tumor initiating cells derived from colorectal liver metastases: trials, tribulations and a cautionary note. PMID: 25658706 Ref: Microsatellite instability: an update. PMID: 25701956 Ref: Single-walled carbon nanotubes functionalized with aptamer and piperazine-polyethylenimine derivative for targeted siRNA delivery into breast cancer cells. PMID: 25712164 Ref: Sensitive ELISA Method for the Measurement of Catabolites of Antibody-Drug Conjugates (ADCs) in Target Cancer Cells. PMID: 25738394 Ref: Circulating tumor cell levels are elevated in colorectal cancer patients with high tumor burden in the liver. PMID: 25785486 Ref: Metastatic colon cancer cell populations contain more cancer stem-like cells with a higher susceptibility to natural killer cell-mediated lysis compared with primary colon cancer cells. PMID: 25789015 Ref: The effects of folic acid on global DNA methylation and colonosphere formation in colon cancer cell lines. PMID: 25804133 Ref: Circulating tumor cell isolation during resection of colorectal cancer lung and liver metastases: a prospective trial with different detection techniques. PMID: 25807199 Ref: A protocol for exosome isolation and characterization: evaluation of ultracentrifugation, density-gradient separation, and immunoaffinity capture methods. PMID: 25820723 Ref: TP53 loss creates therapeutic vulnerability in colorectal cancer. PMID: 25901683 Ref: Childhood cancers in families with and without Lynch syndrome. PMID: 25963852 Ref: Expression of EpCAM and Wnt/ beta-catenin in human colon cancer. PMID: 25966221 Ref: Construction of interference vector targeting Ep-CAM gene and its effects on colorectal cancer cell proliferation. PMID: 26028961 Ref: BMP-2 induces motility and invasiveness by promoting colon cancer stemness through STAT3 activation. PMID: 26124007 Ref: Colorectal cancer-derived tumor spheroids retain the characteristics of original tumors. PMID: 26185002 Ref: Superior Performance of Aptamer in Tumor Penetration over Antibody: Implication of Aptamer-Based Theranostics in Solid Tumors. PMID: 26199647 Ref: Expression changes in epithelial cell adhesion molecule during colorectal cancer tumorigenesis. PMID: 26214441 Ref: Cytokeratin-20 and Survivin-Expressing Circulating Tumor Cells Predict Survival in Metastatic Colorectal Cancer Patients by a Combined Immunomagnetic qRT-PCR Approach. PMID: 26227487 Ref: An anti-EpCAM antibody EpAb2-6 for the treatment of colon cancer. PMID: 26317650 Ref: LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging. PMID: 26318819 Ref: Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells. PMID: 26352531 Ref: Impact of chronic exposure to bevacizumab on EpCAM-based detection of circulating tumor cells. PMID: 26543336 Ref: Exploring Different Strategies for Efficient Delivery of Colorectal Cancer Therapy. PMID: 26569228 Ref: Functional Characterization and Drug Response of Freshly Established Patient-Derived Tumor Models with CpG Island Methylator Phenotype. PMID: 26618628 Ref: Verification of ALDH Activity as a Biomarker in Colon Cancer Stem Cells-Derived HT-29 Cell Line. PMID: 26634106 Ref: Genetic variants within the hTERT gene and the risk of colorectal cancer in Lynch syndrome. PMID: 26807197 |
Ref: Lynch syndrome in the 21st century: clinical perspectives. PMID: 26224055 Ref: Cancer stem cells in human digestive tract malignancies. PMID: 26446457 Ref: Clinicopathologic, molecular, and prognostic implications of the loss of EPCAM expression in colorectal carcinoma. PMID: 26528695 Ref: Identification of a Japanese Lynch syndrome patient with large deletion in the 3' region of the EPCAM gene. PMID: 26613680 Ref: EpCAM aptamer-functionalized mesoporous silica nanoparticles for efficient colon cancer cell-targeted drug delivery. PMID: 26690044 Ref: miR-137 Regulates the Tumorigenicity of Colon Cancer Stem Cells through the Inhibition of DCLK1. PMID: 26747706 Ref: Contribution of in vitro comparison of colorectal carcinoma cells from primary and metastatic lesions to elucidation of mechanisms of tumor progression and response to anticancer therapy. PMID: 26790446 Ref: Tankyrase 1 inhibitior XAV939 increases chemosensitivity in colon cancer cell lines via inhibition of the Wnt signaling pathway. PMID: 26820603 Ref: Identifying cancer origin using circulating tumor cells. PMID: 26828696 Ref: Rapid detection of germline mutations for hereditary gastrointestinal polyposis/cancers using HaloPlex target enrichment and high-throughput sequencing technologies. PMID: 26837502 Ref: Biodistribution and PET Imaging of Labeled Bispecific T Cell-Engaging Antibody Targeting EpCAM. PMID: 26848172 Ref: Predominant expression of truncated EpCAM is associated with a more aggressive phenotype and predicts poor overall survival in colorectal cancer. PMID: 26996277 Ref: Loss of TINCR expression promotes proliferation, metastasis through activating EpCAM cleavage in colorectal cancer. PMID: 27009809 Ref: The Architecture and Function of Monoclonal Antibody-Functionalized Mesoporous Silica Nanoparticles Loaded with Mifepristone: Repurposing Abortifacient for Cancer Metastatic Chemoprevention. PMID: 27027489 Ref: Expression Patterns of Cancer Stem Cell Markers During Specific Celecoxib Therapy in Multistep Rat Colon Carcinogenesis Bioassays. PMID: 27039721 Ref: The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking beta-Catenin/TCF Regulated Transcription. PMID: 27047543 Ref: Adhesion molecules in peritoneal dissemination: function, prognostic relevance and therapeutic options. PMID: 27074785 Ref: Extensive surface protein profiles of extracellular vesicles from cancer cells may provide diagnostic signatures from blood samples. PMID: 27086589 Ref: Tumour-associated circulating microparticles: A novel liquid biopsy tool for screening and therapy monitoring of colorectal carcinoma and other epithelial neoplasia. PMID: 27127176 Ref: Enhanced ADCC and NK Cell Activation of an Anticarcinoma Bispecific Antibody by Genetic Insertion of a Modified IL-15 Cross-linker. PMID: 27157665 Ref: Reduction in membranous immunohistochemical staining for the intracellular domain of epithelial cell adhesion molecule correlates with poor patient outcome in primary colorectal adenocarcinoma. PMID: 27330354 Ref: Analysis of circulating tumor cells in colorectal cancer liver metastasis patients before and after cryosurgery. PMID: 27415969 Ref: Genetic/Familial High-Risk Assessment: Colorectal Version 1.2016, NCCN Clinical Practice Guidelines in Oncology. PMID: 27496117 Ref: Characterization of cancer stem cells from different grades of human colorectal cancer. PMID: 27507615 Ref: The Impact of Receiving Predictive Genetic Information about Lynch Syndrome on Individual Colonoscopy and Smoking Behaviors. PMID: 27528600 Ref: miRNA profiling of circulating EpCAM(+) extracellular vesicles: promising biomarkers of colorectal cancer. PMID: 27576678 Ref: Detection of Proteome Changes in Human Colon Cancer Induced by Cell Surface Binding of Growth-Inhibitory Human Galectin-4 Using Quantitative SILAC-Based Proteomics. PMID: 27801591 Ref: EpCAM as multi-tumour target for near-infrared fluorescence guided surgery. PMID: 27842504 Ref: Enumeration and targeted analysis of KRAS, BRAF and PIK3CA mutations in CTCs captured by a label-free platform: Comparison to ctDNA and tissue in metastatic colorectal cancer. PMID: 27863403 Ref: Transcriptome and long noncoding RNA sequencing of three extracellular vesicle subtypes released from the human colon cancer LIM1863 cell line. PMID: 27917920 Ref: Monitoring of Circulating Tumor Cells by a Combination of Immunomagnetic Enrichment and RT-PCR in Colorectal Cancer Patients Undergoing Surgery. PMID: 28028983 |
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