Primary Site >> Pancreatic Cancer

Gene >> EP300

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Ref: Intracellular signaling of the TGF-beta superfamily by Smad proteins.
PMID: 10667205
Ref: Regulation of epithelial cell growth by ZBP-89: potential relevance in pancreatic cancer.
PMID: 12622418
Ref: No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer.
PMID: 15217503
Ref: Trichostatin A induces transforming growth factor beta type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/p300 to a Sp1.NF-Y complex.
PMID: 15647279
Ref: Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells.
PMID: 16525728
Ref: G-rich oligonucleotides inhibit HIF-1alpha and HIF-2alpha and block tumor growth.
PMID: 19755960
Ref: Clinicopathological significance of cell cycle regulatory factors and differentiation-related factors in pancreatic neoplasms.
PMID: 20335778
Ref: Mutant K-Ras increases GSK-3beta gene expression via an ETS-p300 transcriptional complex in pancreatic cancer.
PMID: 21441955
Ref: The tyrosine kinase c-Src directly mediates growth factor-induced Notch-1 and Furin interaction and Notch-1 activation in pancreatic cancer cells.
PMID: 22479394
Ref: MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer.
PMID: 22869720
Ref: Three-dimensional collagen I promotes gemcitabine resistance in vitro in pancreatic cancer cells through HMGA2-dependent histone acetyltransferase expression.
PMID: 23696899
Ref: A perylene derivative regulates HIF-1alpha and Stat3 signaling pathways.
PMID: 24485121
Ref: LB-1 Exerts Antitumor Activity in Pancreatic Cancer by Inhibiting HIF-1alpha and Stat3 Signaling.
PMID: 25655308
Ref: Exome-level comparison of primary well-differentiated neuroendocrine tumors and their cell lines.
PMID: 26087898
Ref: Altering cancer transcriptomes using epigenomic inhibitors.
PMID: 26191083
Ref: A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer.
PMID: 26695438
Ref: P300 inhibition enhances gemcitabine-induced apoptosis of pancreatic cancer.
PMID: 27322077
Ref: Inhibition of hypoxic response decreases stemness and reduces tumorigenic signaling due to impaired assembly of HIF1 transcription complex in pancreatic cancer.
PMID: 28801636
Ref: Deciphering microRNA targets in pancreatic cancer using miRComb R package.
PMID: 29464088
Ref: Differentiation Therapy Targeting the beta-Catenin/CBP Interaction in Pancreatic Cancer.
PMID: 29596326
Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
PMID: 29786110
Ref: Transcriptional regulation of O-GlcNAc homeostasis is disrupted in pancreatic cancer.
PMID: 30037904