Primary Site >> Colorectal Cancer

Gene >> EME1

  • 2006
  • 2008
  • 2009
  • 2016
Ref: Haploinsufficiency of the Mus81-Eme1 endonuclease activates the intra-S-phase and G2/M checkpoints and promotes rereplication in human cells.
PMID: 16456034
Ref: The EGFR-STAT3 oncogenic pathway up-regulates the Eme1 endonuclease to reduce DNA damage after topoisomerase I inhibition.
PMID: 18245483
Ref: Functional evidence for Eme1 as a marker of cisplatin resistance.
PMID: 19267403
Ref: Radiosensitisation of human colorectal cancer cells by ruthenium(II) arene anticancer complexes.
PMID: 26867983