Primary Site >> Esophagus Cancer

Gene >> EIF4E

  • 2006
  • 2011
  • 2012
  • 2015
  • 2018
Ref: Expression of the eukaryotic translation initiation factor 4E (eIF4E) and 4E-BP1 in esophageal cancer.
PMID: 16375881
 Ref: MDM2 is overexpressed and regulated by the eukaryotic translation initiation factor 4E (eIF4E) in human squamous cell carcinoma of esophagus.
PMID: 21080085
 Ref: Cap-dependent mRNA translation and the ubiquitin-proteasome system cooperate to promote ERBB2-dependent esophageal cancer phenotype.
PMID: 22767218
 Ref: The 4E-BP1/eIF4E ratio is a determinant for rapamycin response in esophageal cancer cells.
PMID: 25439783
 Ref: Genetic and pharmacological inhibition of eIF4E effectively targets esophageal cancer cells and augments 5-FU's efficacy.
PMID: 30174840