Primary Site >> Colorectal Cancer

Gene >> EIF2S1

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Ref: Levels, phosphorylation status and cellular localization of translational factor eIF2 in gastrointestinal carcinomas.
PMID: 10841309
 Ref: Induction of apoptosis in human cancer cells by candidaspongiolide, a novel sponge polyketide.
PMID: 18728285
 Ref: Arctigenin blocks the unfolded protein response and shows therapeutic antitumor activity.
PMID: 20232300
 Ref: Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells--gene expression profiling implies endoplasmic reticulum stress.
PMID: 22027281
 Ref: The non-steroidal anti-inflammatory drug indomethacin activates the eIF2alpha kinase PKR, causing a translational block in human colorectal cancer cells.
PMID: 22268531
Ref: alpha-Mangostin Reduced ER Stress-mediated Tumor Growth through Autophagy Activation.
PMID: 23396851
 Ref: The involvement of endoplasmic reticulum stress in the suppression of colorectal tumorigenesis by tolfenamic acid.
PMID: 24104354
Ref: Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1.
PMID: 24113185
 Ref: A new tellurium-containing amphiphilic molecule induces apoptosis in HCT116 colon cancer cells.
PMID: 24530428
Ref: A functional role for Smad7 in sustaining colon cancer cell growth and survival.
PMID: 24556688
Ref: Combined NADPH oxidase 1 and interleukin 10 deficiency induces chronic endoplasmic reticulum stress and causes ulcerative colitis-like disease in mice.
PMID: 25014110
 Ref: Diterpenoid Tanshinones, the extract from Danshen (Radix Salviae Miltiorrhizae) induced apoptosis in nine human cancer cell lines.
PMID: 28459519
 Ref: Proteins that interact with calgranulin B in the human colon cancer cell line HCT-116.
PMID: 28036279
Ref: TEOA, a triterpenoid from Actinidia eriantha, induces autophagy in SW620 cells via endoplasmic reticulum stress and ROS-dependent mitophagy.
PMID: 28211011
Ref: Smad7 knockdown activates protein kinase RNA-associated eIF2alpha pathway leading to colon cancer cell death.
PMID: 28300830
 Ref: Resistant starch prevents tumorigenesis of dimethylhydrazine-induced colon tumors via regulation of an ER stress-mediated mitochondrial apoptosis pathway.
PMID: 29393371
Ref: The Immunome of Colon Cancer: Functional In Silico Analysis of Antigenic Proteins Deduced from IgG Microarray Profiling.
PMID: 29505855
Ref: Time-dependent shotgun proteomics revealed distinct effects of an organoruthenium prodrug and its activation product on colon carcinoma cells.
PMID: 30106070
Ref: Klotho suppresses colorectal cancer through modulation of the unfolded protein response.
PMID: 30232408