Primary Site >> Pancreatic Cancer
Gene >> EGF
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Ref: Production of somatomedin-like activity by human adult tumor-derived, transformed, and normal cell cultures and by cultured rat hepatocytes: effects of culture conditions and of epidermal growth factor (urogastrone). PMID: 6099216 |
Ref: Stimulation by somatostatin of dephosphorylation of membrane proteins in pancreatic cancer MIA PaCa-2 cell line. PMID: 2857131 Ref: Binding and processing of epidermal growth factor in Panc-I human pancreatic carcinoma cells. PMID: 2985903 Ref: Recycling of epidermal growth factor in a human pancreatic carcinoma cell line. PMID: 2994064 |
Ref: Hormonal control of pancreatic cancer growth. PMID: 2883646 Ref: Pancreatic cancer in the Syrian hamster induced by N-nitrosobis(2-oxopropyl)-amine: cocarcinogenic effect of epidermal growth factor. PMID: 3009003 |
Ref: Membrane receptors for peptides in experimental and human pancreatic cancers. PMID: 2573055 Ref: Attenuated processing of epidermal growth factor in the face of marked degradation of transforming growth factor-alpha. PMID: 2788651 |
Ref: Expression of and response to growth regulatory peptides by two human pancreatic carcinoma cell lines. PMID: 2199964 Ref: Epidermal growth factor and its receptors in human pancreatic carcinoma. PMID: 2343041 Ref: Epidermal growth factor stimulation and metastatic rate in human pancreatic carcinoma cell lines. PMID: 2395372 |
Ref: Effects of epidermal growth factor and analogues of luteinizing hormone-releasing hormone and somatostatin on phosphorylation and dephosphorylation of tyrosine residues of specific protein substrates in various tumors. PMID: 1672042 Ref: Transforming growth factor alpha and epidermal growth factor in human pancreatic cancer. PMID: 1707959 Ref: Differential binding and biological activities of epidermal growth factor and transforming growth factor alpha in a human pancreatic cancer cell line. PMID: 1933884 |
Ref: [Gene expression of TGF alpha, TGF beta 1 and C-erbB2 oncogene in human pancreatic carcinoma cell lines]. PMID: 7909745 Ref: Hormonal therapy of pancreatic carcinoma. Rationale and perspectives. PMID: 8103783 Ref: [Expression of EGF and its mRNA in human pancreatic carcinoma cell lines and in vivo tumor lines]. PMID: 8168178 Ref: Transforming growth factor alpha is trophic to pancreatic cancer in vivo. PMID: 8174961 Ref: Inhibition of pancreatic cancer cell growth in vitro by the tyrphostin group of tyrosine kinase inhibitors. PMID: 8260363 |
Ref: Expression of EGF, TGF-alpha, EGFR and c-erbB2 genes and their gene products in human pancreatic carcinoma cell lines. PMID: 7947634 Ref: [Growth factors in gynecology]. PMID: 8089608 |
Ref: Effect of gastrointestinal hormones and synthetic analogues on the growth of pancreatic cancer. PMID: 7558455 |
Ref: Elevation of intracellular cyclic adenosine monophosphate inhibits the epidermal growth factor signal transduction pathway and cellular growth in pancreatic adenocarcinoma cell lines. PMID: 8751604 Ref: Expression of epidermal and transforming growth factors in pancreatic cancer. PMID: 21594491 |
Ref: Trophic effects by epidermal growth factor on duodenal mucosa and exocrine pancreas in rats. PMID: 9058082 Ref: Clinicopathological significance of epidermal growth factor and its receptor in human pancreatic cancer. PMID: 9427790 |
Ref: Establishment and characterization of a new hamster pancreatic cancer cell line: the biological activity and the binding characteristics of EGF or TGF-alpha. PMID: 9520090 Ref: Prognostic significance of molecular alterations in human pancreatic carcinoma--an immunohistological study. PMID: 9641888 Ref: Current concepts in pancreatic cancer: symposium summary. PMID: 9821173 Ref: Epidermal growth factor and its receptor as prognostic indicators in Chinese patients with pancreatic cancer. PMID: 9891528 |
Ref: Expression and differential regulation of connective tissue growth factor in pancreatic cancer cells. PMID: 10023684 Ref: Serum growth factors in patients with pancreatic cancer. PMID: 10050105 Ref: Human PACAP response gene 1 (p22/PRG1): proliferation-associated expression in pancreatic carcinoma cells. PMID: 10231843 Ref: Serum and correspondent tissue measurements of epidermal growth factor (EGF) and epidermal growth factor receptor (EGF-R). Clinical relevance in pancreatic cancer and chronic pancreatitis. PMID: 10360220 Ref: Activation of MAP kinases in growth responsive pancreatic cancer cells. PMID: 10433520 Ref: Growth inhibition of experimental pancreatic cancers and sustained reduction in epidermal growth factor receptors during therapy with hormonal peptide analogs. PMID: 10480336 |
Ref: Inhibitory effect of a long-acting somatostatin analogue on EGF-stimulated cell proliferation in Capan-2 cells. PMID: 10761690 Ref: Expression of somatostatin receptor subtypes and growth inhibition in human exocrine pancreatic cancers. PMID: 11180877 |
Ref: Pancreatic cancer cells require an EGF receptor-mediated autocrine pathway for proliferation in serum-free conditions. PMID: 11286473 Ref: Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors. PMID: 11406567 Ref: Improved gene transfer efficiency to primary and established human pancreatic carcinoma target cells via epidermal growth factor receptor and integrin-targeted adenoviral vectors. PMID: 11438831 |
Ref: 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis. PMID: 11832446 Ref: [Molecular pathways of pancreatic carcinogenesis]. PMID: 12483152 |
Ref: Expression and regulation of the novel vascular endothelial growth factor receptor neuropilin-1 by epidermal growth factor in human pancreatic carcinoma. PMID: 12910515 |
Ref: Neurotensin and EGF induce synergistic stimulation of DNA synthesis by increasing the duration of ERK signaling in ductal pancreatic cancer cells. PMID: 15389644 Ref: Effects of single, double or triple combinations of octreotide, galanin and serotonin on a human pancreatic cancer cell line. PMID: 15736059 Ref: Epidermal growth factor mediates detachment from and invasion through collagen I and Matrigel in Capan-1 pancreatic cancer cells. PMID: 15801978 Ref: Effects of triple treatment with octreotide, galanin and serotonin on a human pancreas cancer cell line in xenografts. PMID: 15944923 |
Ref: Epithelial growth factor-induced phosphorylation of caveolin 1 at tyrosine 14 stimulates caveolae formation in epithelial cells. PMID: 16332692 Ref: Epidermal growth factor promotes invasiveness of pancreatic cancer cells through NF-kappaB-mediated proteinase productions. PMID: 16340751 Ref: Inactivation of Rho GTPases by p190 RhoGAP reduces human pancreatic cancer cell invasion and metastasis. PMID: 16776779 |
Ref: Human Mena+11a isoform serves as a marker of epithelial phenotype and sensitivity to epidermal growth factor receptor inhibition in human pancreatic cancer cell lines. PMID: 18676769 Ref: Phosphoproteome and transcriptome analyses of ErbB ligand-stimulated MCF-7 cells. PMID: 18820370 Ref: Cancer stem cells: how can we target them? PMID: 19075661 |
Ref: EGF promotes invasion by PANC-1 cells through Rac1/ROS-dependent secretion and activation of MMP-2. PMID: 19116140 Ref: LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites. PMID: 19129242 Ref: Specific cross-talk between epidermal growth factor receptor and integrin alphavbeta5 promotes carcinoma cell invasion and metastasis. PMID: 19208836 Ref: Serine protease inhibitor Kazal type 1 promotes proliferation of pancreatic cancer cells through the epidermal growth factor receptor. PMID: 19737965 Ref: EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells. PMID: 19804359 |
Ref: A new drug delivery method of bispecific ligand-directed toxins, which reduces toxicity and promotes efficacy in a model of orthotopic pancreatic cancer. PMID: 20182395 Ref: Evolution of systemic therapy for advanced pancreatic cancer. PMID: 20397918 Ref: Epidermal growth factor induces HCCR expression via PI3K/Akt/mTOR signaling in PANC-1 pancreatic cancer cells. PMID: 20423485 Ref: Metronomic gemcitabine suppresses tumour growth, improves perfusion, and reduces hypoxia in human pancreatic ductal adenocarcinoma. PMID: 20531411 Ref: Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors. PMID: 21108830 |
Ref: A novel 3-dimensional culture system uncovers growth stimulatory actions by TGFbeta in pancreatic cancer cells. PMID: 21613822 Ref: Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer. PMID: 21729304 Ref: Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells. PMID: 21961726 Ref: Epidermal growth factor down-regulates the expression of neutrophil gelatinase-associated lipocalin (NGAL) through E-cadherin in pancreatic cancer cells. PMID: 24048788 Ref: Dependence of Relative Expression of NTR1 and EGFR on Cell Density and Extracellular pH in Human Pancreatic Cancer Cell Lines. PMID: 24212612 Ref: Growth factor mediated signaling in pancreatic pathogenesis. PMID: 24212642 |
Ref: Accumulation of pro-cancer cytokines in the plasma fraction of stored packed red cells. PMID: 22246854 Ref: JDP2 inhibits the epithelial-to-mesenchymal transition in pancreatic cancer BxPC3 cells. PMID: 22535371 Ref: Epidermal growth factor enhances MPC-83 pancreatic cancer cell migration through the upregulation of aquaporin 3. PMID: 22735833 Ref: Imaging EGFR phosphorylation in intact human pancreatic carcinoma cells. PMID: 22773576 Ref: Inhibitory effect of a Ras homologue member I on pancreatic cancer and its modulation on epithelium growth factor receptor-Ras-Raf-mitogen-activated protein kinase/extracellular regulated protein kinase/1/2 pathway. PMID: 22776648 Ref: Single nucleotide polymorphisms of genes for EGF, TGF-beta and TNF-alpha in patients with pancreatic carcinoma. PMID: 22990108 Ref: Induction of mouse pancreatic ductal differentiation, an in vitro assay. PMID: 23093463 Ref: Insights into erlotinib action in pancreatic cancer cells using a combined experimental and mathematical approach. PMID: 23180942 Ref: Etiology and oncogenesis of pancreatic carcinoma. PMID: 23213974 |
Ref: Altered sphingolipid metabolism in patients with metastatic pancreatic cancer. PMID: 24970174 |
Ref: microRNA-10b enhances pancreatic cancer cell invasion by suppressing TIP30 expression and promoting EGF and TGF-beta actions. PMID: 24096486 Ref: Inhibitory effects of prostaglandin E2 on collagen synthesis and cell proliferation in human stellate cells from pancreatic head adenocarcinoma. PMID: 24912820 Ref: A stem cell medium containing neural stimulating factor induces a pancreatic cancer stem-like cell-enriched population. PMID: 25118635 |
Ref: Gli1 promotes transforming growth factor-beta1- and epidermal growth factor-induced epithelial to mesenchymal transition in pancreatic cancer cells. PMID: 25979438 Ref: [Advance in the biology of pancreatic of cancer]. PMID: 26118878 Ref: EGF augments TGFbeta-induced epithelial-mesenchymal transition by promoting SHP2 binding to GAB1. PMID: 26359300 |
Ref: Phase II trial of epidermal growth factor ointment for patients with Erlotinib-related skin effects. PMID: 26041481 Ref: Phase I trial of vandetanib in combination with gemcitabine and capecitabine in patients with advanced solid tumors with an expanded cohort in pancreatic and biliary cancers. PMID: 26715573 |
Ref: microRNA-10b enhances pancreatic cancer cell invasion by suppressing TIP30 expression and promoting EGF and TGF-beta actions. PMID: 28604742 |
Ref: Enhanced selective cellular uptake and cytotoxicity of epidermal growth factor-conjugated liposomes containing curcumin on EGFR-overexpressed pancreatic cancer cells. PMID: 29157028 Ref: Impact of targeting transforming growth factor beta-2 with antisense OT-101 on the cytokine and chemokine profile in patients with advanced pancreatic cancer. PMID: 29785126 Ref: Variable Effects of Growth Factors on Developmental Gene Expression in Pancreatic Cancer Cells. PMID: 30168063 |