Primary Site >> Stomach Cancer
Gene >> E2F1
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Ref: Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors. PMID: 9192806 |
Ref: UCN-01 suppresses thymidylate synthase gene expression and enhances 5-fluorouracil-induced apoptosis in a sequence-dependent manner. PMID: 9748140 |
Ref: Expression of the E2F family in human gastrointestinal carcinomas. PMID: 10225440 Ref: Expression of p27Kip1, cyclin E and E2F-1 in primary and metastatic tumors of gastric carcinoma. PMID: 10425291 |
Ref: Genetic and epigenetic alterations in multistep carcinogenesis of the stomach. PMID: 10779229 |
Ref: UCN-01 suppresses E2F-1 mediated by ubiquitin-proteasome-dependent degradation. PMID: 11297263 |
Ref: The Epstein-Barr virus immediate-early protein BZLF1 induces expression of E2F-1 and other proteins involved in cell cycle progression in primary keratinocytes and gastric carcinoma cells. PMID: 12438580 |
Ref: Exogenous wild-type p16INK4A gene induces delayed cell proliferation and promotes chemosensitivity through decreased pRB and increased E2F-1 expressions. PMID: 12792810 Ref: Chromosome arm 20q gains and other genomic alterations in esophageal squamous cell carcinoma, as analyzed by comparative genomic hybridization and fluorescence in situ hybridization. PMID: 14696419 |
Ref: Expression of thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase, E2F-1, Bak, Bcl-X, and Bcl-2, and clinical outcomes for gastric cancer patients treated with bolus 5-fluorouracil. PMID: 14654896 |
Ref: Transcription factor E2F-1 is upregulated in human gastric cancer tissues and its overexpression suppresses gastric tumor cell proliferation. PMID: 17641417 Ref: [Construction of a eukaryotic vector expressing E2F-1 Gene and its effect on proliferation of gastric cancer cell line MKN-45]. PMID: 17927874 Ref: Meta- and gene set analysis of stomach cancer gene expression data. PMID: 17978572 |
Ref: Impact of E2F-1 expression on clinical outcome of gastric adenocarcinoma patients with adjuvant chemoradiation therapy. PMID: 18172256 Ref: E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. PMID: 18328430 Ref: [Inhibitory effects of transcription factor E2F-1 siRNA on invasion and proliferation of gastric cancer cell line MGC803]. PMID: 18799027 |
Ref: Overexpression of E2F-1 inhibits progression of gastric cancer in vitro. PMID: 19289176 Ref: Short interfering RNA directed against the E2F-1 gene suppressing gastric cancer progression in vitro. PMID: 19360313 Ref: Adenovirus vector-mediated upregulation of spermidine /spermine N1-acetyltransferase impairs human gastric cancer growth in vitro and in vivo. PMID: 19686286 Ref: [Effects of E2F-1 overexpression on apoptosis of gastric cancer cells and expressions of apoptosis-related genes]. PMID: 19895738 |
Ref: miRNA-331-3p directly targets E2F1 and induces growth arrest in human gastric cancer. PMID: 20510161 |
Ref: Antiproliferative mechanism of a cannabinoid agonist by cell cycle arrest in human gastric cancer cells. PMID: 21312237 Ref: Lentivirus-mediated RNA interference targeting E2F-1 inhibits human gastric cancer MGC-803 cell growth in vivo. PMID: 21869593 |
Ref: Pharmacologic synergy between dual phosphoinositide-3-kinase and mammalian target of rapamycin inhibition and 5-fluorouracil in PIK3CA mutant gastric cancer cells. PMID: 22336586 Ref: Dracorhodin perchlorate inhibits PI3K/Akt and NF-kappaB activation, up-regulates the expression of p53, and enhances apoptosis. PMID: 22711363 Ref: Maspin genetically and functionally associates with gastric cancer by regulating cell cycle progression. PMID: 22962304 |
Ref: E2F transcription factors and digestive system malignancies: how much do we know? PMID: 23745020 Ref: MiR-19b/20a/92a regulates the self-renewal and proliferation of gastric cancer stem cells. PMID: 23868977 Ref: [Inhibitory effect of E2F-1-silencing lentivirus vector on chemoresistance of subcutaneous human gastric cancer in nude mice]. PMID: 24332051 Ref: [Effects of E2F-1 gene silencing on cisplatin chemosensitivity of human gastric cancer SGC-7901/DDP cells]. PMID: 24369233 |
Ref: Reversal of multidrug resistance in gastric cancer cells by E2F-1 downregulation in vitro and in vivo. PMID: 24038122 Ref: Expressions and clinical significances of c-MET, p-MET and E2f-1 in human gastric carcinoma. PMID: 24393368 Ref: Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: results from the EPIC-EURGAST study. PMID: 24643999 Ref: [Reversion of multidrug resistance of human gastric cancer SGC7901/DDP cells by E2F-1 gene silencing]. PMID: 24785275 Ref: Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a. PMID: 24810364 Ref: Decreased expression of long noncoding RNA GAS5 indicates a poor prognosis and promotes cell proliferation in gastric cancer. PMID: 24884417 Ref: Ablation of galectin-3 induces p27(KIP1)-dependent premature senescence without oncogenic stress. PMID: 24971481 Ref: Long noncoding RNA associated-competing endogenous RNAs in gastric cancer. PMID: 25124853 Ref: Overexpression of E2F1 in human gastric carcinoma is involved in anti-cancer drug resistance. PMID: 25466554 Ref: Epithelial cell-derived periostin functions as a tumor suppressor in gastric cancer through stabilizing p53 and E-cadherin proteins via the Rb/E2F1/p14ARF/Mdm2 signaling pathway. PMID: 25486483 |
Ref: Long noncoding RNA ANRIL promotes non-small cell lung cancer cell proliferation and inhibits apoptosis by silencing KLF2 and P21 expression. PMID: 25504755 Ref: E2F-1 overexpression inhibits human gastric cancer MGC-803 cell growth in vivo. PMID: 25593464 Ref: Overexpression of E2F mRNAs associated with gastric cancer progression identified by the transcription factor and miRNA co-regulatory network analysis. PMID: 25646628 Ref: Regulatory mechanisms of transcription factors and target genes on gastric cancer by bioinformatics method. PMID: 25916094 Ref: Resected gastric cancer with D2 dissection: advances in adjuvant chemoradiotherapy and radiotherapy techniques. PMID: 26004039 Ref: The reciprocal regulation loop of Notch2 pathway and miR-23b in controlling gastric carcinogenesis. PMID: 26041881 Ref: Genome-wide analysis of the oxyntic proliferative isthmus zone reveals ASPM as a possible gastric stem/progenitor cell marker over-expressed in cancer. PMID: 26178168 |
Ref: A candidate gastric stem/progenitor cell marker revealed by genome-wide analysis. PMID: 26310200 Ref: Decreased long noncoding RNA MIR31HG is correlated with poor prognosis and contributes to cell proliferation in gastric cancer. PMID: 26692098 Ref: CHK1 expression in Gastric Cancer is modulated by p53 and RB1/E2F1: implications in chemo/radiotherapy response. PMID: 26867682 Ref: E2F1-induced upregulation of long noncoding RNA LINC00668 predicts a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically silencing of CKIs. PMID: 27036039 Ref: Tspan5 is an independent favourable prognostic factor and suppresses tumour growth in gastric cancer. PMID: 27223087 Ref: LncRNA HOXA11-AS Promotes Proliferation and Invasion of Gastric Cancer by Scaffolding the Chromatin Modification Factors PRC2, LSD1, and DNMT1. PMID: 27651312 Ref: miR-135a promotes gastric cancer progression and resistance to oxaliplatin. PMID: 27683111 Ref: E2F-1 promotes DAPK2-induced anti-tumor immunity of gastric cancer cells by targeting miR-34a. PMID: 27704360 Ref: Helicobacter pylori infection related long noncoding RNA (lncRNA) AF147447 inhibits gastric cancer proliferation and invasion by targeting MUC2 and up-regulating miR-34c. PMID: 27835575 |
Ref: The prolyl oligopeptidase inhibitor SUAM-14746 attenuates the proliferation of human breast cancer cell lines in vitro. PMID: 28070831 Ref: HMGA2-FOXL2 Axis Regulates Metastases and Epithelial-to-Mesenchymal Transition of Chemoresistant Gastric Cancer. PMID: 28119367 Ref: E2F1 induces TINCR transcriptional activity and accelerates gastric cancer progression via activation of TINCR/STAU1/CDKN2B signaling axis. PMID: 28569791 Ref: miR-218 suppresses gastric cancer cell cycle progression through the CDK6/Cyclin D1/E2F1 axis in a feedback loop. PMID: 28634044 |
Ref: Stemness Is Enhanced in Gastric Cancer by a SET/PP2A/E2F1 Axis. PMID: 29330298 Ref: In vitro and in vivo effects of miRNA-19b/20a/92a on gastric cancer stem cells and the related mechanism. PMID: 29333091 Ref: Expression of TAp73alpha affects the therapy effect of chemotherapy drugs in gastric cancer. PMID: 29362023 Ref: Somatic mutations and increased lymphangiogenesis observed in a rare case of intramucosal gastric carcinoma with lymph node metastasis. PMID: 29535844 Ref: Silkworm Pupa Protein Hydrolysate Induces Mitochondria-Dependent Apoptosis and S Phase Cell Cycle Arrest in Human Gastric Cancer SGC-7901 Cells. PMID: 29597296 Ref: Inhibitory effects of isocryptotanshinone on gastric cancer. PMID: 29915371 Ref: Long non-coding RNA NNT-AS1 sponges miR-424/E2F1 to promote the tumorigenesis and cell cycle progression of gastric cancer. PMID: 30006956 Ref: E2F1 induces LSINCT5 transcriptional activity and promotes gastric cancer progression by affecting the epithelial-mesenchymal transition. PMID: 30127643 Ref: The silencing of long non-coding RNA ANRIL suppresses invasion, and promotes apoptosis of retinoblastoma cells through ATM-E2F1 signaling pathway. PMID: 30355646 |