Primary Site >> Colorectal Cancer
Gene >> DVL2
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Ref: Comparative integromics on FAT1, FAT2, FAT3 and FAT4. PMID: 16865240 |
Ref: Expression of Wnt pathway components frizzled and disheveled in colon cancer arising in patients with inflammatory bowel disease. PMID: 17671721 |
Ref: Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation. PMID: 20639871 Ref: Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer. PMID: 20663899 |
Ref: HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression. PMID: 21317929 Ref: Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations. PMID: 21531761 |
Ref: High expression of IGFBP7 in fibroblasts induced by colorectal cancer cells is co-regulated by TGF-beta and Wnt signaling in a Smad2/3-Dvl2/3-dependent manner. PMID: 24427302 Ref: Dissecting the signaling pathways associated with the oncogenic activity of MLK3 P252H mutation. PMID: 24628919 Ref: An unconventional KITENIN/ErbB4-mediated downstream signal of EGF upregulates c-Jun and the invasiveness of colorectal cancer cells. PMID: 24893630 |
Ref: Myc-interacting zinc-finger protein 1 positively regulates Wnt signalling by protecting Dishevelled from Dapper1-mediated degradation. PMID: 25558878 Ref: Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development. PMID: 25871009 Ref: Wnt ligand-dependent activation of the negative feedback regulator Nkd1. PMID: 25904337 |
Ref: DDX3 promotes tumor invasion in colorectal cancer via the CK1epsilon/Dvl2 axis. PMID: 26892600 |
Ref: KITENIN functions as a fine regulator of ErbB4 expression level in colorectal cancer via protection of ErbB4 from E3-ligase Nrdp1-mediated degradation. PMID: 27648936 Ref: Wnt5b-associated exosomes promote cancer cell migration and proliferation. PMID: 27762090 Ref: Dishevelled stability is positively regulated by PKCzeta-mediated phosphorylation induced by Wnt agonists. PMID: 28366812 Ref: Down-regulation of LRP1B in colon cancer promoted the growth and migration of cancer cells. PMID: 28408316 Ref: Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis. PMID: 28825595 |
Ref: beta-catenin-independent regulation of Wnt target genes by RoR2 and ATF2/ATF4 in colon cancer cells. PMID: 29453334 Ref: HMGA2 enhances 5-fluorouracil chemoresistance in colorectal cancer via the Dvl2/Wnt pathway. PMID: 29515783 |