Primary Site >> Colorectal Cancer

Gene >> DRAXIN

  • 2011
  • 2013
  • 2015
  • 2018
Ref: Draxin inhibits axonal outgrowth through the netrin receptor DCC.
PMID: 21957262
Ref: N-terminal horseshoe conformation of DCC is functionally required for axon guidance and might be shared by other neural receptors.
PMID: 23038776
Ref: Repulsive axon guidance by Draxin is mediated by protein Kinase B (Akt), glycogen synthase kinase-3beta (GSK-3beta) and microtubule-associated protein 1B.
PMID: 25775433
Ref: Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex.
PMID: 26659141
Ref: Draxin regulates hippocampal neurogenesis in the postnatal dentate gyrus by inhibiting DCC-induced apoptosis.
PMID: 29339781
Ref: Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC.
PMID: 29503192