Primary Site >> Esophagus Cancer

Gene >> DPYD

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Ref: [Chemoradiotherapy with low-dose cisplatin and 5-FU for advanced esophageal cancer].
PMID: 11086419
Ref: [Immunohistochemical study of dihydropyrimidine dehydrogenase (DPD) and p53 in biopsied specimens of esophageal cancer before chemoradiotherapy].
PMID: 11707971
Ref: Biopsy specimen microvessel density is a useful prognostic marker in patients with T(2-4)M(0) esophageal cancer treated with chemoradiotherapy.
PMID: 11801548
Ref: [A complete response after neoadjuvant chemotherapy for advanced gastric cancer with esophageal invasion].
PMID: 11816467
Ref: Role of dihydropyrimidine dehydrogenase activity in patients with esophageal cancer.
PMID: 12552994
Ref: High level concentration of pyrimidine nucleoside phosphorylase in esophageal squamous cell carcinoma but no correlation with clinicopathological parameters.
PMID: 14641294
Ref: Downregulation of TS, DPD, ERCC1, GST-Pi, EGFR, and HER2 gene expression after neoadjuvant three-modality treatment in patients with esophageal cancer.
PMID: 15737843
Ref: Prediction of response to neoadjuvant chemotherapy in carcinomas of the upper gastrointestinal tract.
PMID: 17163161
Ref: Relationship between expression of 5-fluorouracil metabolic enzymes and 5-fluorouracil sensitivity in esophageal carcinoma cell lines.
PMID: 18197934
Ref: Dihydropyrimidine dehydrogenase and orotate phosphoribosyltransferase in esophageal cancer patients: Correlation with clinicopathological factors and prognosis.
PMID: 21479475
Ref: [Correlation between clinicopathological factors and enzymatic activity of orotate phosphoribosyl transferase (OPRT), dihydropyrimidine dehydrogenase (DPD) in esophageal cancer].
PMID: 20647710
Ref: [Four resected cases with basaloid carcinoma of esophagus--comparison of 5-FU-related enzymes (thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), orotate phosphoribosyl transferase (OPRT)) between basaloid carcinoma and squamous cell carcin
PMID: 21084814
Ref: Thymidylate synthetase and dihydropyrimidine dehydrogenase mRNA levels in esophageal cancer.
PMID: 22866080
Ref: Roles of thymidylate synthase and dihydropyrimidine dehydrogenase expression in blood as predictors of response to multimodal therapy in esophageal cancer.
PMID: 21982526
Ref: Factors affecting the sensitivity of human-derived esophageal carcinoma cell lines to 5-fluorouracil and cisplatin.
PMID: 23420099
Ref: Prognostic impact of blood biomarkers TS and DPD in neoadjuvant-treated esophageal cancer patients.
PMID: 25750278
Ref: A Case of Hyperammonemia Associated with High Dihydropyrimidine Dehydrogenase Activity.
PMID: 27195162
Ref: Molecular Markers for the Prediction of Minor Response to Neoadjuvant Chemoradiation in Esophageal Cancer: Results of the Prospective Cologne Esophageal Response Prediction (CERP) Study.
PMID: 27741011
Ref: Long noncoding RNA LINC00261 induces chemosensitization to 5-fluorouracil by mediating methylation-dependent repression of DPYD in human esophageal cancer.
PMID: 30226808