Primary Site >> Biliary tract Cancer

Gene >> DPYD

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Ref: Drug sensitivity and drug resistance profiles of human intrahepatic cholangiocarcinoma cell lines.
PMID: 15884115
 Ref: A phase I study of eniluracil/5-FU in combination with radiation therapy for potentially resectable and/or unresectable cancer of the pancreas and distal biliary tract.
PMID: 16466986
Ref: Thymidylate synthase and dihydropyrimidine dehydrogenase expressions in gallbladder cancer.
PMID: 16619549
Ref: Deficient expression of the DPD gene is caused by epigenetic modification in biliary tract cancer cells, and induces high sensitivity to 5-FU treatment.
PMID: 16820886
 Ref: Successful treatment of advanced gallbladder cancer with an anticancer drug S-1: assessment based on intratumoral gene.
PMID: 19093184
 Ref: Thymidylate synthase and dihydropyrimidine dehydrogenase are upregulated in pancreatic and biliary tract cancers.
PMID: 19571608
 Ref: Role of dihydropyrimidine dehydrogenase and thymidylate synthase expression in immunohistochemistry of intrahepatic cholangiocarcinoma.
PMID: 20880064
Ref: Impact of intratumoral thymidylate synthase expression on prognosis after surgical resection for ampullary carcinoma.
PMID: 21360535
 Ref: Role of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA in intrahepatic cholangiocarcinoma.
PMID: 22143355
Ref: Role of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expressions in gallbladder carcinoma.
PMID: 22270332
Ref: Orotate phosphoribosyl transferase mRNA expression and the response of cholangiocarcinoma to 5-fluorouracil.
PMID: 22912546
 Ref: Prognostic significance of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in biliary tract cancer patients receiving adjuvant 5-fluorouracil-based chemotherapy.
PMID: 24649282
 Ref: Successful curative resection of gallbladder cancer following S-1 chemotherapy: A case report and review of the literature.
PMID: 25360167
 Ref: Prognostic Value of Excision Repair Cross-Complementing Gene 1, Dihydropyrimidine Dehydrogenase, and Human Equilibrative Nucleotide Transporter 1 Expression and Their Implications for Adjuvant Treatment in Patients With Ampullary Carcinoma.
PMID: 25906447