Primary Site >> Colorectal Cancer
Gene >> DPP4
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Ref: Immunohistological evidence, obtained with monoclonal antibodies, of small intestinal brush border hydrolases in human colon cancers and foetal colons. PMID: 6389373 |
Ref: Effects of short chain fatty acids on a new human colon carcinoma cell line (LIM1215). PMID: 3804021 |
Ref: A new colon carcinoma cell line (LIM1863) that grows as organoids with spontaneous differentiation into crypt-like structures in vitro. PMID: 3567898 |
Ref: Isolation of a cDNA probe for the human intestinal dipeptidylpeptidase IV and assignment of the gene locus DPP4 to chromosome 2. PMID: 1977364 Ref: Growth adaptation to methotrexate of HT-29 human colon carcinoma cells is associated with their ability to differentiate into columnar absorptive and mucus-secreting cells. PMID: 2205381 |
Ref: Expression of dipeptidyl aminopeptidase IV during enterocytic differentiation of human colon cancer (Caco-2) cells. PMID: 1672667 Ref: Intracellular localization and endocytosis of brush border enzymes in the enterocyte-like cell line Caco-2. PMID: 1674471 Ref: Effects of epidermal growth factor on diamine oxidase expression and cell growth in Caco-2 cells. PMID: 1681737 |
Ref: A survey of membrane peptidases in two human colonic cell lines, Caco-2 and HT-29. PMID: 1318037 Ref: Dipeptidyl peptidase IV (CD 26) gene expression in enterocyte-like colon cancer cell lines HT-29 and Caco-2. Cloning of the complete human coding sequence and changes of dipeptidyl peptidase IV mRNA levels during cell differentiation. PMID: 1347043 Ref: Intestinal brush-border-associated enzymes: co-ordinated expression in colorectal cancer. PMID: 1349006 Ref: Polarized distribution of neutral endopeptidase 24.11 at the cell surface of cultured human intestinal epithelial Caco-2 cells. PMID: 1361726 Ref: Expression and different polarity of aminopeptidase N in normal human colonic mucosa and colonic tumors. PMID: 1375588 Ref: Experimental photodynamic therapy with a copper metal vapor laser in colorectal cancer. PMID: 1399126 |
Ref: Comparative tumor morphogenesis of two human colon adenocarcinoma cell clones xenografted in the immunosuppressed newborn rat. PMID: 7903648 Ref: The tumor promoter 12-O-tetradecanoylphorbol-13-acetate blocks differentiation of HT-29 human colon cancer cells. PMID: 8227206 |
Ref: A novel co-stimulatory T cell antigen co-expressed on renal cell carcinoma. PMID: 7495750 |
Ref: Resistance of the human colon carcinoma cell line HCT-8 to methotrexate results in selection of cells with features of enterocytic differentiation. PMID: 9495241 Ref: Expression patterns of the ectopeptidases aminopeptidase N/CD13 and dipeptidyl peptidase IV/CD26: immunoultrastructural topographic localization on different types of cultured cells. PMID: 9587627 Ref: Loss of epithelial differentiation markers and acquisition of vimentin expression after xenograft with laminin-1 enhance migratory and invasive abilities of human colon cancer cells LoVo C5. PMID: 9697308 |
Ref: In vitro analysis of the role of DCC in mucus-secreting intestinal differentiation. PMID: 10328236 Ref: Follicle-like structures formed by intestinal cell lines derived from the HT29-D4 adenocarcinoma cell line: morphological and functional characterization. PMID: 10399829 |
Ref: Postmitotic differentiation of colon carcinoma caco-2 cells does not prevent reentry in the cell cycle and tumorigenicity. PMID: 10891291 Ref: Different expression of some molecular markers in sporadic cancer of the left and right colon. PMID: 10958329 Ref: Preoperative serum CD26 levels: diagnostic efficiency and predictive value for colorectal cancer. PMID: 11027426 |
Ref: Soluble dipeptidyl peptidase IV (CD-26) in serum of patients with colorectal carcinoma. PMID: 12458328 |
Ref: Clinical interest of the combined use of serum CD26 and alpha-L-fucosidase in the early diagnosis of colorectal cancer. PMID: 15258327 |
Ref: Adenosine down-regulates the surface expression of dipeptidyl peptidase IV on HT-29 human colorectal carcinoma cells: implications for cancer cell behavior. PMID: 15215186 Ref: PT-100, a small molecule dipeptidyl peptidase inhibitor, has potent antitumor effects and augments antibody-mediated cytotoxicity via a novel immune mechanism. PMID: 15289357 |
Ref: Profiling of the tetraspanin web of human colon cancer cells. PMID: 16467180 Ref: Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatase(s) and reducing ERK1/2 activity via a novel pathway. PMID: 16611738 Ref: Adenosine metabolism and cancer. Focus on "Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatases and reducing ERK1/2 activity via a novel pathway". PMID: 16707553 Ref: DPPIV inhibitors extend GLP-2 mediated tumour promoting effects on intestinal cancer cells. PMID: 16908079 |
Ref: In vitro differentiation of HT-29 M6 mucus-secreting colon cancer cells involves a trychostatin A and p27(KIP1)-inducible transcriptional program of gene expression. PMID: 17311291 |
Ref: Highly fucosylated N-glycan ligands for mannan-binding protein expressed specifically on CD26 (DPPVI) isolated from a human colorectal carcinoma cell line, SW1116. PMID: 19129245 Ref: On the origin of serum CD26 and its altered concentration in cancer patients. PMID: 19557413 Ref: Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice. PMID: 19920354 Ref: Soluble CD26 levels and its association to epidemiologic parameters in a sample population. PMID: 20075514 |
Ref: A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer. PMID: 20569697 Ref: Serum CD26 is related to histopathological polyp traits and behaves as a marker for colorectal cancer and advanced adenomas. PMID: 20584285 Ref: A study of three polymorphic sites of ADA gene in colon cancer. PMID: 20590444 |
Ref: Mechanisms of confluence-dependent expression of CD26 in colon cancer cell lines. PMID: 21284881 Ref: The dietary flavonoid apigenin enhances the activities of the anti-metastatic protein CD26 on human colon carcinoma cells. PMID: 21298326 Ref: Potential of soluble CD26 as a serum marker for colorectal cancer detection. PMID: 21773075 Ref: Common cancer stem cell gene variants predict colon cancer recurrence. PMID: 21918173 |
Ref: Comparison and combination of blood-based inflammatory markers with faecal occult blood tests for non-invasive colorectal cancer screening. PMID: 22454079 Ref: Plasma seprase and DPP4 levels as markers of disease and prognosis in cancer. PMID: 22674411 Ref: A locked, dimeric CXCL12 variant effectively inhibits pulmonary metastasis of CXCR4-expressing melanoma cells due to enhanced serum stability. PMID: 22869557 Ref: A novel multiplex-protein array for serum diagnostics of colon cancer: a case-control study. PMID: 22954206 |
Ref: SSEA-3 as a novel amplifying cancer cell surface marker in colorectal cancers. PMID: 23175153 Ref: Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. PMID: 23230278 Ref: Differential roles of Hath1, MUC2 and P27Kip1 in relation with gamma-secretase inhibition in human colonic carcinomas: a translational study. PMID: 23409082 Ref: Cytometric profiling of CD133+ cells in human colon carcinoma cell lines identifies a common core phenotype and cell type-specific mosaics. PMID: 23709346 Ref: Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species. PMID: 23916687 Ref: Dipeptidyl peptidase 10, a novel prognostic marker in colorectal cancer. PMID: 24142639 |
Ref: Prognostic significance of CD26 in patients with colorectal cancer. PMID: 24870408 Ref: Postoperative serum levels of sCD26 for surveillance in colorectal cancer patients. PMID: 25210927 |
Ref: Surface profiles of live colorectal cancer cells and tumor infiltrating lymphocytes from surgical samples correspond to prognostic categories. PMID: 25445327 Ref: Serum sCD26 for colorectal cancer screening in family-risk individuals: comparison with faecal immunochemical test. PMID: 25461801 Ref: CD26-positive/CD326-negative circulating cancer cells as prognostic markers for colorectal cancer recurrence. PMID: 25624884 Ref: Characterization and propagation of tumor initiating cells derived from colorectal liver metastases: trials, tribulations and a cautionary note. PMID: 25658706 Ref: Dipeptidyl-peptidase IV activity is correlated with colorectal cancer prognosis. PMID: 25790122 Ref: Prominin-1 (CD133, AC133) and dipeptidyl-peptidase IV (CD26) are indicators of infinitive growth in colon cancer cells. PMID: 25973297 Ref: Suppression of lung metastases by the CD26/DPP4 inhibitor Vildagliptin in mice. PMID: 26233333 Ref: Chemotherapeutic agents attenuate CXCL12-mediated migration of colon cancer cells by selecting for CXCR4-negative cells and increasing peptidase CD26. PMID: 26552750 Ref: Evaluation of Anti Cancer Effects of DPP-4 Inhibitors in Colon Cancer- An Invitro Study. PMID: 26816911 |
Ref: Isolation of colorectal cancer stem-like cells. PMID: 25535115 Ref: Prognostic relevance of stromal CD26 expression in rectal cancer after chemoradiotherapy. PMID: 26370256 Ref: The dipeptidyl peptidase-4 inhibitor sitagliptin suppresses mouse colon tumorigenesis in type 2 diabetic mice. PMID: 26573958 Ref: Acquisition of anticancer drug resistance is partially associated with cancer stemness in human colon cancer cells. PMID: 27748801 |
Ref: The Identifications and Clinical Implications of Cancer Stem Cells in Colorectal Cancer. PMID: 28237538 Ref: Cancer Stem Cell Gene Variants in CD44 Predict Outcome in Stage II and Stage III Colon Cancer Patients. PMID: 28373475 Ref: Emergence of CD26+ Cancer Stem Cells with Metastatic Properties in Colorectal Carcinogenesis. PMID: 28545226 Ref: Involvement of CRF2 signaling in enterocyte differentiation. PMID: 28811708 Ref: The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity. PMID: 28813679 |
Ref: Release of multifunctional peptides from kiwicha (Amaranthus caudatus) protein under in vitro gastrointestinal digestion. PMID: 30066387 Ref: ALDH1A3 upregulation and spontaneous metastasis formation is associated with acquired chemoresistance in colorectal cancer cells. PMID: 30143021 Ref: miR-372 and miR-373 enhance the stemness of colorectal cancer cells by repressing differentiation signaling pathways. PMID: 30171794 |