Primary Site >> Stomach Cancer

Gene >> DNMT3A

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Ref: DNA methylation status of hMLH1, p16(INK4a), and CDH1 is not associated with mRNA expression levels of DNA methyltransferase and DNA demethylase in gastric carcinomas.
PMID: 11496321
 Ref: The expression and clinical significance of DNA methyltransferase proteins in human gastric cancer.
PMID: 18253830
 Ref: The presence of a methylation fingerprint of Helicobacter pylori infection in human gastric mucosae.
PMID: 19035455
 Ref: A functional polymorphism in the DNA methyltransferase-3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma.
PMID: 20128888
Ref: Genetic and epigenetic alteration in gastric carcinogenesis.
PMID: 21054651
 Ref: Helicobacter pylori infection promotes methylation of WWOX gene in human gastric cancer.
PMID: 21466786
Ref: Clinical significance of the expression of DNA methyltransferase proteins in gastric cancer.
PMID: 21887466
 Ref: Association of the DNMT3A -448A>G polymorphism with genetic susceptibility to colorectal cancer.
PMID: 22740930
Ref: Risk-association of DNA methyltransferases polymorphisms with gastric cancer in the Southern Chinese population.
PMID: 22942708
Ref: DNMT3A rs36012910 A>G polymorphism and gastric cancer susceptibility in a Chinese population.
PMID: 23053986
 Ref: Mutational analysis of DNMT3A gene in acute leukemias and common solid cancers.
PMID: 23031157
Ref: miR-200b and miR-200c as prognostic factors and mediators of gastric cancer cell progression.
PMID: 23995857
Ref: DNMT3a rs1550117 polymorphism association with increased risk of Helicobacter pylori infection.
PMID: 24289567
Ref: DNMT3A -448A>G polymorphism and the risk for hepatocellular carcinoma.
PMID: 24649006
 Ref: Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: results from the EPIC-EURGAST study.
PMID: 24643999
Ref: A novel functional TagSNP Rs7560488 in the DNMT3A1 promoter is associated with susceptibility to gastric cancer by modulating promoter activity.
PMID: 24667323
Ref: DNA methyltransferase3a expression is an independent poor prognostic indicator in gastric cancer.
PMID: 25009393
 Ref: Deregulation between miR-29b/c and DNMT3A is associated with epigenetic silencing of the CDH1 gene, affecting cell migration and invasion in gastric cancer.
PMID: 25874772
Ref: Quercetin-induced apoptosis prevents EBV infection.
PMID: 26059439
Ref: DNA methyltransferase 3A promotes cell proliferation by silencing CDK inhibitor p18INK4C in gastric carcinogenesis.
PMID: 26350239
Ref: DNA methyltransferase 3a rs1550117 genetic polymorphism predicts poor survival in gastric cancer patients.
PMID: 26823816
 Ref: Epigenetically deregulated miR-200c is involved in a negative feedback loop with DNMT3a in gastric cancer cells.
PMID: 27498672
Ref: DNMT1, DNMT3A and DNMT3B Polymorphisms Associated With Gastric Cancer Risk: A Systematic Review and Meta-analysis.
PMID: 27789275
 Ref: MiR-143 inhibits cell proliferation and invasion by targeting DNMT3A in gastric cancer.
PMID: 28718369
Ref: DNMT3A-mediated down-regulation of microRNA-105 promotes gastric cancer cell proliferation.
PMID: 28829505
 Ref: Procaine is a specific DNA methylation inhibitor with anti-tumor effect for human gastric cancer.
PMID: 28926119
Ref: Effect of lenalidomide on the human gastric cancer cell line SGC7901/vincristine Notch signaling.
PMID: 29578180
Ref: DNA methyltransferase 3A isoform b contributes to repressing E-cadherin through cooperation of DNA methylation and H3K27/H3K9 methylation in EMT-related metastasis of gastric cancer.
PMID: 29717263
Ref: Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer.
PMID: 29802960
Ref: Association of five genetic variations in DNMT1 and DNMT3A with gastric cancer in a Chinese population.
PMID: 29956566
Ref: APC gene is modulated by hsa-miR-135b-5p in both diffuse and intestinal gastric cancer subtypes.
PMID: 30376837