Primary Site >> Pancreatic Cancer
Gene >> DLL4
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Ref: Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells. PMID: 16525728 |
Ref: Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer. PMID: 19258443 |
Ref: Blockade of delta-like ligand 4 signaling inhibits both growth and angiogenesis of pancreatic cancer. PMID: 20182391 |
Ref: High expression of delta-like ligand 4 predicts poor prognosis after curative resection for pancreatic cancer. PMID: 21822553 Ref: Anti-DLL4 has broad spectrum activity in pancreatic cancer dependent on targeting DLL4-Notch signaling in both tumor and vasculature cells. PMID: 22952347 |
Ref: Delta like ligand 4 induces impaired chemo-drug delivery and enhanced chemoresistance in pancreatic cancer. PMID: 23200678 |
Ref: Overexpressions of DLL4 and CD105 are Associated with Poor Prognosis of Patients with Pancreatic Ductal Adenocarcinoma. PMID: 25986715 |
Ref: Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells. PMID: 26673007 |
Ref: Leptin-Notch signaling axis is involved in pancreatic cancer progression. PMID: 27999190 |
Ref: Expression of Notch receptors and their ligands in pancreatic ductal adenocarcinoma. PMID: 29896227 |