Primary Site >> Stomach Cancer

Gene >> DLL4

  • 2006
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  • 2017
  • 2018
Ref: Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells.
PMID: 16525728
Ref: Notch signaling in gastrointestinal tract (review).
PMID: 17143535
Ref: Combination DLL4 with Jagged1-siRNA can enhance inhibition of the proliferation and invasiveness activity of human gastric carcinoma by Notch1/VEGF pathway.
PMID: 22020917
Ref: beta -Elemene-Attenuated Tumor Angiogenesis by Targeting Notch-1 in Gastric Cancer Stem-Like Cells.
PMID: 23710217
Ref: Clinical implications of DLL4 expression in gastric cancer.
PMID: 23898884
Ref: Influence of up-regulation of Notch ligand DLL4 on biological behaviors of human gastric cancer cells.
PMID: 23901223
Ref: Role of Notch signaling pathway in gastric cancer: a meta-analysis of the literature.
PMID: 25083094
Ref: Simultaneous blockade of VEGF and Dll4 by HD105, a bispecific antibody, inhibits tumor progression and angiogenesis.
PMID: 27049350
Ref: Helicobacter pylori Infection of Gastric Epithelial Cells Affects NOTCH Pathway In Vitro.
PMID: 27073072
Ref: DLL4 overexpression increases gastric cancer stem/progenitor cell self-renewal ability and correlates with poor clinical outcome via Notch-1 signaling pathway activation.
PMID: 27891816
Ref: Generation and characterization of an anti-delta like ligand-4 Nanobody to induce non-productive angiogenesis.
PMID: 29246751
Ref: Concurrent Treatment with Anti-DLL4 Enhances Antitumor and Proapoptotic Efficacy of a gamma-Secretase Inhibitor in Gastric Cancer.
PMID: 29571073
Ref: Isolation and identification of chemotherapy-enriched sphere-forming cells from a patient with gastric cancer.
PMID: 29744869