Primary Site >> Colorectal Cancer
Gene >> DLL1
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Ref: Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells. PMID: 16525728 Ref: Gefitinib in combination with 5-fluorouracil (5-FU)/folinic acid and irinotecan in patients with 5-FU/oxaliplatin- refractory colorectal cancer: a phase I/II study of the Arbeitsgemeinschaft fur Internistische Onkologie (AIO). PMID: 17202826 |
Ref: Notch signaling in gastrointestinal tract (review). PMID: 17143535 |
Ref: Phase I-II trial of concurrent capecitabine and oxaliplatin with preoperative intensity-modulated radiotherapy in patients with locally advanced rectal cancer. PMID: 18164861 |
Ref: Gefitinib in combination with capecitabine as second-line therapy in patients with advanced colorectal cancer (aCRC): a phase I/II study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). PMID: 20215798 |
Ref: The Notch ligand Delta-like 1 integrates inputs from TGFbeta/Activin and Wnt pathways. PMID: 21473864 |
Ref: [Expression of JAG1 and DLL1 genes in colorectal cancer and its clinical significance]. PMID: 22539391 Ref: Epigenetic silencing of Notch signaling in gastrointestinal cancers. PMID: 23085543 |
Ref: A phase I trial of imatinib in combination with mFOLFOX6-bevacizumab in patients with advanced colorectal cancer. PMID: 23108698 Ref: A phase I trial of isolated hepatic perfusion (IHP) using 5-FU and oxaliplatin in patients with unresectable isolated liver metastases from colorectal cancer. PMID: 23575907 Ref: Phase I trial of the combination of the Akt inhibitor nelfinavir and chemoradiation for locally advanced rectal cancer. PMID: 23647753 Ref: Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1. PMID: 24185040 |
Ref: A phase Ib study of linsitinib (OSI-906), a dual inhibitor of IGF-1R and IR tyrosine kinase, in combination with everolimus as treatment for patients with refractory metastatic colorectal cancer. PMID: 25335932 |
Ref: Phase Ib study of poly-epitope peptide vaccination to thymidylate synthase (TSPP) and GOLFIG chemo-immunotherapy for treatment of metastatic colorectal cancer patients. PMID: 27141384 |
Ref: Metformin depresses overactivated Notch1/Hes1 signaling in colorectal cancer patients with type 2 diabetes mellitus. PMID: 28177944 Ref: Kaiso differentially regulates components of the Notch signaling pathway in intestinal cells. PMID: 28637464 |
Ref: Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer. PMID: 29899427 |