Primary Site >> Liver Cancer

Gene >> DKK3

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Ref: A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines.
PMID: 10652205
Ref: Dickkopf-3/REIC functions as a suppressor gene of tumor growth.
PMID: 15516983
Ref: [Detection of reduced mRNA expression of REIC/Dkk-3 gene in human primary hepatocellular carcinoma].
PMID: 17064477
Ref: Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.
PMID: 17675336
Ref: Methylation of Dickkopf-3 as a prognostic factor in cirrhosis-related hepatocellular carcinoma.
PMID: 20135726
Ref: Epigenetic silencing of sFRP1 activates the canonical Wnt pathway and contributes to increased cell growth and proliferation in hepatocellular carcinoma.
PMID: 22351518
Ref: Dysregulated expression of dickkopfs for potential detection of hepatocellular carcinoma.
PMID: 24809435
Ref: In-depth analysis of secretome and N-glycosecretome of human hepatocellular carcinoma metastatic cell lines shed light on metastasis correlated proteins.
PMID: 27014972
Ref: DKK3 expression in hepatocytes defines susceptibility to liver steatosis and obesity.
PMID: 27016281
Ref: Combination of DKK1 and AFP improves diagnostic accuracy of hepatocellular carcinoma compared with either marker alone.
PMID: 27458854
Ref: GATA4 promotes hepatoblastoma cell proliferation by altering expression of miR125b and DKK3.
PMID: 27788486
Ref: Promising therapeutic efficacy of a novel reduced expression in immortalized cells/dickkopf-3 expressing adenoviral vector for hepatocellular carcinoma.
PMID: 28168749
Ref: Dishevelled 1, a pivotal positive regulator of the Wnt signalling pathway, mediates 5-fluorouracil resistance in HepG2 cells.
PMID: 29583038
Ref: Antiproliferative Effects of Epigenetic Modifier Drugs Through E-cadherin Up-regulation in Liver Cancer Cell Lines.
PMID: 29735783