Primary Site >> Colorectal Cancer
Gene >> DDIT3
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Ref: Long-term remission durability and functional status of patients treated for diffuse histiocytic lymphoma with the CHOP regimen. PMID: 6379123 |
Ref: Comparison of costs for infusion versus bolus chemotherapy administration: analysis of five standard chemotherapy regimens in three common tumors--Part one. Model projections for cost based on charges. PMID: 8674006 Ref: Comparison of costs for infusion versus bolus chemotherapy administration--Part two. Use of charges versus reimbursement for cost basis. PMID: 8674007 Ref: Bile acid activation of the gadd153 promoter and of p53-independent apoptosis: relevance to colon cancer. PMID: 17180111 |
Ref: Bile acid-induced activation of activator protein-1 requires both extracellular signal-regulated kinase and protein kinase C signaling. PMID: 10748108 Ref: Increased expression of the transcription factors CCAAT-enhancer binding protein-beta (C/EBBeta) and C/EBzeta (CHOP) correlate with invasiveness of human colorectal cancer. PMID: 10760820 |
Ref: Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells. PMID: 11950812 Ref: Activator protein-1 and CCAAT/enhancer-binding protein mediated GADD153 expression is involved in deoxycholic acid-induced apoptosis. PMID: 12069855 Ref: Genomic effects of polyamide/DNA interactions on mRNA expression. PMID: 12144926 |
Ref: Induction of GADD gene expression by phenethylisothiocyanate in human colon adenocarcinoma cells. PMID: 14635187 Ref: Monoclonal antibodies in human cancer. PMID: 14988743 |
Ref: Targets of 17beta-oestradiol-induced apoptosis in colon cancer cells: a mechanism for the protective effects of hormone replacement therapy? PMID: 15128281 Ref: Curcumin-induced GADD153 gene up-regulation in human colon cancer cells. PMID: 15271854 Ref: CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells. PMID: 15322075 Ref: Cell cycle-related signaling pathways modulated by peripheral benzodiazepine receptor ligands in colorectal cancer cells. PMID: 15474510 |
Ref: The C/EBP homologous protein CHOP (GADD153) is an inhibitor of Wnt/TCF signals. PMID: 16434966 Ref: Dihydroxyphenylethanol induces apoptosis by activating serine/threonine protein phosphatase PP2A and promotes the endoplasmic reticulum stress response in human colon carcinoma cells. PMID: 16524888 Ref: Risk of second cancer after treatment of aggressive non-Hodgkin's lymphoma; an EORTC cohort study. PMID: 17043014 |
Ref: Hypoxia induces p53-dependent transactivation and Fas/CD95-dependent apoptosis. PMID: 16917513 Ref: Elevated gadd153/chop expression during resveratrol-induced apoptosis in human colon cancer cells. PMID: 17049495 Ref: Curcumin-induced GADD153 upregulation: modulation by glutathione. PMID: 17171638 Ref: Fenretinide up-regulates DR5/TRAIL-R2 expression via the induction of the transcription factor CHOP and combined treatment with fenretinide and TRAIL induces synergistic apoptosis in colon cancer cell lines. PMID: 17273769 Ref: Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells. PMID: 17283163 Ref: Resveratrol induces pro-apoptotic endoplasmic reticulum stress in human colon cancer cells. PMID: 17914584 |
Ref: 6-Shogaol induces apoptosis in human colorectal carcinoma cells via ROS production, caspase activation, and GADD 153 expression. PMID: 18384088 Ref: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through activation of c-jun N-terminal kinase. PMID: 18460448 Ref: Growth inhibition of colon cancer cells by polyisoprenylated benzophenones is associated with induction of the endoplasmic reticulum response. PMID: 18470880 Ref: Intrinsically disordered human C/EBP homologous protein regulates biological activity of colon cancer cells during calcium stress. PMID: 18534616 Ref: Rottlerin induces pro-apoptotic endoplasmic reticulum stress through the protein kinase C-delta-independent pathway in human colon cancer cells. PMID: 18807195 Ref: Baicalein overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance via two different cell-specific pathways in cancer cells but not in normal cells. PMID: 18974136 |
Ref: [Treatment of Waldenstrom macroglobulinaemia--the experience of one centre]. PMID: 19227950 Ref: Inhibition of eIF2alpha dephosphorylation inhibits ErbB2-induced deregulation of mammary acinar morphogenesis. PMID: 19754954 |
Ref: The integrated stress response-associated signals modulates intestinal tumor cell growth by NSAID-activated gene 1 (NAG-1/MIC-1/PTGF-beta). PMID: 20130018 Ref: Modulation of stress genes expression profile by nitric oxide-releasing aspirin in Jurkat T leukemia cells. PMID: 20188076 Ref: Differential effects of resveratrol and novel resveratrol derivative, HS-1793, on endoplasmic reticulum stress-mediated apoptosis and Akt inactivation. PMID: 20198347 Ref: Arctigenin blocks the unfolded protein response and shows therapeutic antitumor activity. PMID: 20232300 Ref: Flavokawain B, a novel chalcone from Alpinia pricei Hayata with potent apoptotic activity: Involvement of ROS and GADD153 upstream of mitochondria-dependent apoptosis in HCT116 cells. PMID: 20398749 Ref: HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors. PMID: 20454457 Ref: DHA alters expression of target proteins of cancer therapy in chemotherapy resistant SW620 colon cancer cells. PMID: 20574922 Ref: Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL. PMID: 20837473 |
Ref: The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells. PMID: 20607588 Ref: ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins. PMID: 21127198 Ref: Phloroglucinol derivative MCPP induces cell apoptosis in human colon cancer. PMID: 21268086 Ref: Celecoxib induces cell apoptosis coupled with up-regulation of the expression of VEGF by a mechanism involving ER stress in human colorectal cancer cells. PMID: 21567098 |
Ref: Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins. PMID: 21797841 Ref: Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC delta-independent mechanism. PMID: 22410117 Ref: Acriflavine enhances radiosensitivity of colon cancer cells through endoplasmic reticulum stress-mediated apoptosis. PMID: 22564437 Ref: Autophagy protects against oxaliplatin-induced cell death via ER stress and ROS in Caco-2 cells. PMID: 23226467 |
Ref: Helenalin-induced apoptosis is dependent on production of reactive oxygen species and independent of induction of endoplasmic reticulum stress in renal cell carcinoma. PMID: 23123298 Ref: Trans-10, cis-12 conjugated linoleic acid induced cell death in human colon cancer cells through reactive oxygen species-mediated ER stress. PMID: 23333652 Ref: 20-O-(beta-D-glucopyranosyl)-20(S)-protopanaxadiol induces apoptosis via induction of endoplasmic reticulum stress in human colon cancer cells. PMID: 23381572 Ref: Curcumin induces apoptosis in human gastric carcinoma AGS cells and colon carcinoma HT-29 cells through mitochondrial dysfunction and endoplasmic reticulum stress. PMID: 23881281 Ref: Brefeldin a effectively inhibits cancer stem cell-like properties and MMP-9 activity in human colorectal cancer Colo 205 cells. PMID: 23973996 Ref: Zebularine inhibits tumorigenesis and stemness of colorectal cancer via p53-dependent endoplasmic reticulum stress. PMID: 24225777 |
Ref: Crude extract of Rheum palmatum L induced cell death in LS1034 human colon cancer cells acts through the caspase-dependent and -independent pathways. PMID: 23315830 Ref: Peroxisome proliferator-activated receptor gamma ligand troglitazone and TRAIL synergistically induce apoptosis. PMID: 24276615 Ref: Triapine and a more potent dimethyl derivative induce endoplasmic reticulum stress in cancer cells. PMID: 24378333 Ref: OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro. PMID: 24464048 Ref: A new tellurium-containing amphiphilic molecule induces apoptosis in HCT116 colon cancer cells. PMID: 24530428 Ref: Role of ATF3 in synergistic cancer cell killing by a combination of HDAC inhibitors and agonistic anti-DR5 antibody through ER stress in human colon cancer cells. PMID: 24530917 Ref: Modulation of endoplasmic reticulum (ER) stress-induced autophagy by C/EBP homologous protein (CHOP) and inositol-requiring enzyme 1alpha (IRE1alpha) in human colon cancer cells. PMID: 24565834 Ref: Silencing of JMJD2B induces cell apoptosis via mitochondria-mediated and death receptor-mediated pathway activation in colorectal cancer. PMID: 24957706 Ref: Vitamin D deficiency impairs rituximab-mediated cellular cytotoxicity and outcome of patients with diffuse large B-cell lymphoma treated with but not without rituximab. PMID: 25135997 Ref: Fucoidan induces cancer cell apoptosis by modulating the endoplasmic reticulum stress cascades. PMID: 25232957 Ref: Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid. PMID: 25269802 Ref: Astragalus saponins modulates colon cancer development by regulating calpain-mediated glucose-regulated protein expression. PMID: 25319833 Ref: Dictyopteris undulata Extract Induces Apoptosis via Induction of Endoplasmic Reticulum Stress in Human Colon Cancer Cells. PMID: 25337580 |
Ref: COX-2- and endoplasmic reticulum stress-independent induction of ULBP-1 and enhancement of sensitivity to NK cell-mediated cytotoxicity by celecoxib in colon cancer cells. PMID: 25218028 Ref: DNA damage and ER stress contribute to oblongifolin C-induced cell killing in Bax/Bak-deficient cells. PMID: 25576357 Ref: Patulin induces apoptosis through ROS-mediated endoplasmic reticulum stress pathway. PMID: 25577197 Ref: Dihydroartemisinin-Induced Apoptosis is Associated with Inhibition of Sarco/Endoplasmic Reticulum Calcium ATPase Activity in Colorectal Cancer. PMID: 25701954 Ref: Concomitant non-Hodgkin's lymphoma in colon and liver: report of a rare case and review of literature. PMID: 26045849 Ref: The interplay between GRP78 expression and Akt activation in human colon cancer cells under celecoxib treatment. PMID: 26225471 Ref: Esculetin induces apoptosis in human colon cancer cells by inducing endoplasmic reticulum stress. PMID: 26439795 Ref: Hesperidin inhibits HeLa cell proliferation through apoptosis mediated by endoplasmic reticulum stress pathways and cell cycle arrest. PMID: 26459308 Ref: Non-Hodgkin lymphoma diagnosed by a percutaneous trans-hepatic needle biopsy of portal vein tumor emboli. PMID: 26725360 Ref: [Sensitization of human colon cancer HT-29 cells to TRAIL-induced apoptosis by gambognic acid]. PMID: 26837170 |
Ref: Crude extract of Rheum palmatum L. Induces cell cycle arrest S phase and apoptosis through mitochondrial-dependent pathways in U-2 OS human osteosarcoma cells. PMID: 25689151 Ref: mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation. PMID: 25867072 Ref: TRAIL-Induced Caspase Activation Is a Prerequisite for Activation of the Endoplasmic Reticulum Stress-Induced Signal Transduction Pathways. PMID: 26212606 Ref: Arginine deprivation induces endoplasmic reticulum stress in human solid cancer cells. PMID: 26546743 Ref: Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis. PMID: 26784903 Ref: Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells. PMID: 26859847 Ref: Celecoxib induces apoptosis but up-regulates VEGF via endoplasmic reticulum stress in human colorectal cancer in vitro and in vivo. PMID: 26931344 Ref: Molecular mode of action of NKP-1339 - a clinically investigated ruthenium-based drug - involves ER- and ROS-related effects in colon carcinoma cell lines. PMID: 26988975 Ref: Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment. PMID: 27166181 Ref: Endoplasmic reticulum stress, unfolded protein response and development of colon adenocarcinoma. PMID: 27220766 Ref: Three components of cigarette smoke altered the growth and apoptosis of metastatic colon cancer cells via inducing the synthesis of reactive oxygen species and endoplasmic reticulum stress. PMID: 27262990 Ref: Elucidation of a novel phenformin derivative on glucose-deprived stress responses in HT-29 cells. PMID: 27392906 Ref: Gossypol induces death receptor-5 through activation of ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL. PMID: 27496964 Ref: Ginsenoside compound K sensitizes human colon cancer cells to TRAIL-induced apoptosis via autophagy-dependent and -independent DR5 upregulation. PMID: 27512955 Ref: Bifidobacteria Prevent Tunicamycin-Induced Endoplasmic Reticulum Stress and Subsequent Barrier Disruption in Human Intestinal Epithelial Caco-2 Monolayers. PMID: 27611782 Ref: Gefitinib enhances human colon cancer cells to TRAIL-induced apoptosis of via autophagy- and JNK-mediated death receptors upregulation. PMID: 27629794 Ref: Long-lasting reduction in clonogenic potential of colorectal cancer cells by sequential treatments with 5-azanucleosides and topoisomerase inhibitors. PMID: 27852227 |
Ref: Tunicamycin enhances human colon cancer cells to TRAIL-induced apoptosis by JNK-CHOP-mediated DR5 upregulation and the inhibition of the EGFR pathway. PMID: 27603596 Ref: Morus Rubra Extract Induces Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells Through Endoplasmic Reticulum Stress and Telomerase. PMID: 27880042 Ref: Preclinical study of cinobufagin as a promising anti-colorectal cancer agent. PMID: 27894091 Ref: Apigenin induces both intrinsic and extrinsic pathways of apoptosis in human colon carcinoma HCT-116 cells. PMID: 27959417 Ref: Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress. PMID: 28030835 Ref: 3',5-dihydroxy-3,4',7-trimethoxyflavone-induces ER-stress-associated HCT-116 programmed cell death via redox signaling. PMID: 28103509 Ref: TEOA, a triterpenoid from Actinidia eriantha, induces autophagy in SW620 cells via endoplasmic reticulum stress and ROS-dependent mitophagy. PMID: 28211011 Ref: Smad7 knockdown activates protein kinase RNA-associated eIF2alpha pathway leading to colon cancer cell death. PMID: 28300830 Ref: Endoplasmic reticulum-targeting photosensitizer Hypericin confers chemo-sensitization towards oxaliplatin through inducing pro-death autophagy. PMID: 28392376 Ref: Increased reactive oxygen species levels cause ER stress and cytotoxicity in andrographolide treated colon cancer cells. PMID: 28412728 Ref: Enhanced Susceptibility to 5-Fluorouracil in Human Colon Cancer Cells by Silencing of GRP78. PMID: 28551635 Ref: In vitro additive antitumor effects of dimethoxycurcumin and 5-fluorouracil in colon cancer cells. PMID: 28573788 Ref: Citrinin induces apoptosis in human HCT116 colon cancer cells through endoplasmic reticulum stress. PMID: 29165056 Ref: Molecular crosstalk between ferroptosis and apoptosis: emerging role of ER stress-induced p53-independent PUMA expression. PMID: 29383150 |
Ref: Resistant starch prevents tumorigenesis of dimethylhydrazine-induced colon tumors via regulation of an ER stress-mediated mitochondrial apoptosis pathway. PMID: 29393371 Ref: Antiproliferative effect of p-Coumaric acid targets UPR activation by downregulating Grp78 in colon cancer. PMID: 29879413 Ref: Shikonin Exerts Cytotoxic Effects in Human Colon Cancers by Inducing Apoptotic Cell Death via the Endoplasmic Reticulum and Mitochondria-Mediated Pathways. PMID: 29925224 Ref: Astragaloside attenuates the progression of prostate cancer cells through endoplasmic reticulum stress pathways. PMID: 30128005 Ref: Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5. PMID: 30160785 Ref: Aloe-Emodin Induces Endoplasmic Reticulum Stress-Dependent Apoptosis in Colorectal Cancer Cells. PMID: 30199885 Ref: Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK-mediated DR5 regulation in colorectal cancer. PMID: 30221676 |