Primary Site >> Colorectal Cancer
Gene >> DCTN6
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Ref: Expression of cell-cycle-regulating transcription factor E2F-1 in colorectal carcinomas. PMID: 10738178 |
Ref: Elevated expression of SAG/ROC2/Rbx2/Hrt2 in human colon carcinomas: SAG does not induce neoplastic transformation, but antisense SAG transfection inhibits tumor cell growth. PMID: 11255265 Ref: Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas. PMID: 11335900 Ref: HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2. PMID: 11408350 |
Ref: Piceatannol, a natural analog of resveratrol, inhibits progression through the S phase of the cell cycle in colorectal cancer cell lines. PMID: 11823594 |
Ref: [Stat3 signal transduction pathway orchestrates G1 to S cell cycle transition in colon cancer cells]. PMID: 12920809 |
Ref: Alterations in the expression of the cell cycle regulatory protein cyclin kinase subunit 1 in colorectal carcinoma. PMID: 15073847 Ref: 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes induce peroxisome proliferator-activated receptor gamma-mediated growth inhibition, transactivation, and differentiation markers in colon cancer cells. PMID: 15342379 |
Ref: Ciglitazone-induced p27 gene transcriptional activity is mediated through Sp1 and is negatively regulated by the MAPK signaling pathway. PMID: 15951157 Ref: Molecular targets and anticancer potential of indole-3-carbinol and its derivatives. PMID: 16082211 |
Ref: Induction of apoptosis and cell cycle arrest by a specific c-Jun NH2-terminal kinase (JNK) inhibitor, SP-600125, in gastrointestinal cancers. PMID: 16337741 Ref: Protein kinase C delta inhibits Caco-2 cell proliferation by selective changes in cell cycle and cell death regulators. PMID: 16434969 |
Ref: In vitro differentiation of HT-29 M6 mucus-secreting colon cancer cells involves a trychostatin A and p27(KIP1)-inducible transcriptional program of gene expression. PMID: 17311291 Ref: Regulation of PTEN expression in intestinal epithelial cells by c-Jun NH2-terminal kinase activation and nuclear factor-kappaB inhibition. PMID: 17699782 |
Ref: Multimarker phenotype predicts adverse survival in patients with lymph node-negative colorectal cancer. PMID: 18076013 Ref: Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells. PMID: 18414391 Ref: Mucronulatol from Caribbean propolis exerts cytotoxic effects on human tumor cell lines. PMID: 18538108 Ref: c-myc antisense oligonucleotides sensitize human colorectal cancer cells to chemotherapeutic drugs. PMID: 18802399 |
Ref: Impact of p27mt gene on transplantation model of human colorectal cancer in nude mice. PMID: 19140239 Ref: Inhibition of cyclooxygenase-1 lowers proliferation and induces macroautophagy in colon cancer cells. PMID: 19258012 Ref: Mirk regulates the exit of colon cancer cells from quiescence. PMID: 19542220 Ref: Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft. PMID: 19638451 Ref: A novel histone deacetylase inhibitor, CG0006, induces cell death through both extrinsic and intrinsic apoptotic pathways. PMID: 19644355 |
Ref: The synergistic anticancer effect of troglitazone combined with aspirin causes cell cycle arrest and apoptosis in human lung cancer cells. PMID: 19908241 Ref: A glycoprotein from Laminaria japonica induces apoptosis in HT-29 colon cancer cells. PMID: 20615460 Ref: Identification of Small Molecule Inhibitors of Wee1 Degradation and Mitotic Entry PMID: 23762957 |
Ref: Inhibitory effect and mechanisms of an anthocyanins- and anthocyanidins-rich extract from purple-shoot tea on colorectal carcinoma cell proliferation. PMID: 22404116 |
Ref: Analgesic-antitumor peptide induces apoptosis and inhibits the proliferation of SW480 human colon cancer cells. PMID: 23420047 Ref: Novel MEK inhibitor trametinib and other retinoblastoma gene (RB)-reactivating agents enhance efficacy of 5-fluorouracil on human colon cancer cells. PMID: 23438367 Ref: P27/Kip1 is responsible for magnolol-induced U373 apoptosis in vitro and in vivo. PMID: 23448150 Ref: Melanoidins isolated from heated potato fiber (Potex) affect human colon cancer cells growth via modulation of cell cycle and proliferation regulatory proteins. PMID: 23583803 Ref: Interactions between SAP155 and FUSE-binding protein-interacting repressor bridges c-Myc and P27Kip1 expression. PMID: 23594796 Ref: Expression of Livin in colorectal cancer and its relationship to tumor cell behavior and prognosis. PMID: 24023847 Ref: Notch1-dependent regulation of p27 determines cell fate in colorectal cancer. PMID: 24141420 |
Ref: MicroRNA-200b stimulates tumour growth in TGFBR2-null colorectal cancers by negatively regulating p27/kip1. PMID: 24151081 Ref: [Cell morphology in the dormancy and proliferation stage of colorectal cancer stem cells]. PMID: 24671820 Ref: Pan-Bcl-2 inhibitor obatoclax delays cell cycle progression and blocks migration of colorectal cancer cells. PMID: 25192188 Ref: Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes. PMID: 25200342 Ref: Achyranthes aspera root extracts induce human colon cancer cell (COLO-205) death by triggering the mitochondrial apoptosis pathway and S phase cell cycle arrest. PMID: 25401123 |
Ref: Cks1 proteasomal degradation is induced by inhibiting Hsp90-mediated chaperoning in cancer cells. PMID: 25544127 Ref: DNA fragmentation and cell cycle arrest: a hallmark of apoptosis induced by Ruta graveolens in human colon cancer cells. PMID: 25576270 Ref: CSN5 silencing inhibits invasion and arrests cell cycle progression in human colorectal cancer SW480 and LS174T cells in vitro. PMID: 26045788 Ref: The role of Skp2 and its substrate CDKN1B (p27) in colorectal cancer. PMID: 26114183 Ref: Jianpi Huayu Decoction Inhibits Proliferation in Human Colorectal Cancer Cells (SW480) by Inducing G0/G1-Phase Cell Cycle Arrest and Apoptosis. PMID: 26457107 |
Ref: Crude extract of Rheum palmatum L. Induces cell cycle arrest S phase and apoptosis through mitochondrial-dependent pathways in U-2 OS human osteosarcoma cells. PMID: 25689151 Ref: Radiosensitization of Human Colorectal Cancer Cells by MLN4924: An Inhibitor of NEDD8-Activating Enzyme. PMID: 26082455 Ref: Intestinal-specific activatable Myb initiates colon tumorigenesis in mice. PMID: 26300002 Ref: A novel quinazolinone chalcone derivative induces mitochondrial dependent apoptosis and inhibits PI3K/Akt/mTOR signaling pathway in human colon cancer HCT-116 cells. PMID: 26615871 Ref: The B56gamma3 regulatory subunit-containing protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phospho-Thr157 of p27KIP1. PMID: 26684356 Ref: Dual inhibition of COX-2/5-LOX blocks colon cancer proliferation, migration and invasion in vitro. PMID: 26707712 Ref: Protocatechualdehyde Induces S-Phase Arrest and Apoptosis by Stimulating the p27(KIP1)-Cyclin A/D1-CDK2 and Mitochondrial Apoptotic Pathways in HT-29 Cells. PMID: 27447597 Ref: Role of gamma-glutamyl cyclotransferase as a therapeutic target for colorectal cancer based on the lentivirus-mediated system. PMID: 27500968 Ref: Oxymatrine synergistically enhances antitumor activity of oxaliplatin in colon carcinoma through PI3K/AKT/mTOR pathway. PMID: 27671687 |
Ref: Synthetic lethal interaction of CDK inhibition and autophagy inhibition in human solid cancer cell lines. PMID: 28560460 Ref: Ursodeoxycholic acid inhibits the proliferation of colon cancer cells by regulating oxidative stress and cancer stem-like cell growth. PMID: 28708871 Ref: M4IDP, a zoledronic acid derivative, induces G1 arrest, apoptosis and autophagy in HCT116 colon carcinoma cells via blocking PI3K/Akt/mTOR pathway. PMID: 28751160 Ref: Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway. PMID: 28972559 Ref: Inhibition of cell cycle progression by the hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells. PMID: 29137335 |
Ref: Curcumol induces cell cycle arrest in colon cancer cells via reactive oxygen species and Akt/ GSK3beta/cyclin D1 pathway. PMID: 28684297 Ref: NDRG2 facilitates colorectal cancer differentiation through the regulation of Skp2-p21/p27 axis. PMID: 29343851 Ref: AZD8055 Exerts Antitumor Effects on Colon Cancer Cells by Inhibiting mTOR and Cell-cycle Progression. PMID: 29491070 Ref: The inhibitory effect of Manuka honey on human colon cancer HCT-116 and LoVo cell growth. Part 1: the suppression of cell proliferation, promotion of apoptosis and arrest of the cell cycle. PMID: 29645049 Ref: Construction and characterization of regulated cycle inhibiting factors induced upon Tet-On system in human colon cancer cell lines. PMID: 29923895 Ref: UBA2 promotes proliferation of colorectal cancer. PMID: 30387828 |